Clinical trials: Heart Transplanted Patients
Liver Transplant; Complications, Cardiovascular Complication
Cardiovascular Outcomes in Orthotopic Liver Transplanted Patients (COLT Study)
All patients with orthotopic liver transplantation who are evaluated and followed at each participating centers will be recorded in this study. Within this register a characterization of patients and therapy will be done.
- Conditions
- Liver Transplant; Complications, Cardiovascular Complication, Cardiovascular; Attack, Cardiovascular Stroke
- Trial name
- COLT (NCT05895669)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Coronary Artery Disease, Angina Pectoris
Patient-Reported Preferences Affecting Revascularization Decisions
Selection of a treatment strategy for patients with symptoms due to coronary artery disease requires consideration of patient preferences.
- Trial name
- PREPARED (NCT02272062)
- Testing
- Decision-making tool for coronary artery disease treatment
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery
This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function…
- Trial name
- NCT07006441
- Testing
- Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Cardiovascular Disease
Phase II Study To Evaluate The Safety and Efficacy of Hemoglobin Raffimer in Patients Undergoing First Time CABG Surgery
To evaluate the efficacy of Hemolink™ in combination with Intraoperative Autologous Donation (IAD) versus control (IAD alone) in facilitating avoidance of allogeneic RBC transfusion during and following primary CABG surgery
- Trial name
- NCT00038454
- Testing
- Hemolink (hemoglobin raffimer IV solution)
- Where
- 28 sites in United States, Canada and 1 more
- Volunteers
- 180 people
- Sponsor
- Hemosol
Coronary Artery Bypass Graft Surgery
Effects of Massage Therapy on Sleep After Heart Surgery
The purpose of this study is to evaluate the effects of Massage Therapy for improving the quality of sleep in patients on postoperative period of coronary artery bypass graft surgery (CABG).
- Trial name
- MT and CABG (NCT01095419)
- Testing
- Massage Therapy, Control
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
MI Related Malignant Ventricular Arrhythmia
Effect of Radiofrequency Ablation in Patients With Ventricular Arrhythmia Undergoing CABG
Patients with myocardial infarction related potential malignant ventricular arrhythmia have high risk of sudden death. The aim of this clinical trial is evaluating therapeutic efficacy of unipolar or bipolar radiofrequency…
- Trial name
- RACAVA (NCT02991170)
- Testing
- unipolar or bipolar radiofrequency ablation+CABG, CABG
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Beijing Anzhen Hospital
Three Vessel Coronary Disease
Long-Term Outcomes in Patients With Three-Vessel Disease
The long-term outcome of coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and medical therapy (MT) alone for triple-vessel disease (TVD) patients is controversial.
- Trial name
- NCT05007054
- Testing
- PCI or CABG
- Where
- China
- Volunteers
- 4,300 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Coronary Artery Bypass Graft
Effect of Active Cycle of Breathing Technique as Add on to Routine Chest Physical Therapy on Respiratory Parameters in Coronary Artery Bypass Graft Patients
A controlled trial was conducted to determine the effect of the active cycle of breathing technique (ACBT) in improving respiratory parameters after coronary artery bypass graft surgery.
- Trial name
- CABG ACBT ABG (NCT06705556)
- Testing
- Active cycle of breathing technique, incentive spirometer, percussion, 3-minute of walking, incentive spirometer, percussion, 3-minute of walking
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people
- Sponsor
- Sadaf Bukhari
Patient With Clinically Indicated Invasive Monitoring
ClearSight System CHN Study
The purpose of this clinical trial is to demonstrate that cardiac output (CO) as determined with the Clinical Platform (Model:EV1000A, Software Version:1.9) in a noninvasive manner is comparable to CO as determined by Pulmonary…
- Trial name
- NCT03807622
- Testing
- EV1000NI Clinical Platform: Noninvasive Hemodynamic Monitoring utilizing ClearSight System
- Where
- 3 sites in China
- Volunteers
- 125 people
- Sponsor
- Edwards Lifesciences
Diabetes, Heart Disease
Miami Healthy Heart Initiative a Behavioral Study on Cardiovascular Risk Factors
A study to examine the effectiveness of a multilevel Community Health Workers intervention as an adjunct to routine primary care in reducing CVD risk factors among diabetic Latinos in Miami.
- Conditions
- Diabetes, Heart Disease, Hypertension
- Trial name
- MHHI (NCT01152957)
- Testing
- CARIÑO Project, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Coronary Artery Bypass Graft Surgery, Myocardial Ischemia
MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery)
The purpose of this study is to determine whether MC-1 is effective and safe in reducing cardiovascular and neurological events in patients undergoing high-risk coronary artery bypass surgery
- Conditions
- Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury, Myocardial Revascularization
- Trial name
- NCT00157716
- Testing
- (MC-1) Pyridoxal-5'-phosphate
- Where
- 2 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- Medicure
Low Cardiac Output
The Efficacy of Hypertonic Lactate Solution in CABG(Coronary Artery Bypass Grafting) Patients
Previous clinical trials with 11.2% Hypertonic Ringer's Lactate in post-operative CABG subjects have shown an increase in several cardiac performance parameters, with lesser volume of resuscitation fluid required to reach…
- Trial name
- NCT00529711
- Testing
- Hypertonic lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Xenon, Sevoflurane
A Pre- and Post- Coronary Artery Bypass Graft Implantation Disposed Application of Xenon
The aim of this study is to determine whether xenon - as compared to sevoflurane - can be applied safely in patients for general anesthesia before and after CABG implantation.
- Conditions
- Xenon, Sevoflurane, Anesthetics, Inhalation, Coronary Disease
- Trial name
- CArDiAX (NCT01285271)
- Testing
- Xenon, Sevoflurane
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- RWTH Aachen University
Ischaemic Heart Disease, Contrast-induced Nephropathy
Randomised Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT03736018)
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 688 people
- Sponsor
- Queen Mary University of London
Anomalies in Glucose Metabolism, Coronary Artery Bypass Graft
Evaluation of the Prevalence of anomalIes of Glucose Metabolism in Patients Undergoing a Coronary Artery Bypass Graft (CABG)
The aim of this study is to determine the prevalence of diabetes and non-diabetic glucose metabolism anomalies (glucose intolerance, non-diabetic fasting hyperglycaemia in patients about to undergo coronary artery bypass grafting…
- Trial name
- IMPACT (NCT02855879)
- Testing
- Collection of biological data, Collection of clinical data
- Where
- France
- Volunteers
- 286 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Heart Failure
BeneMACS Study:HeartMate 2 (HM2)Left Ventricular Assist Device (LVAD) Survival in Non Transplant Patients is Equal/Better Than Results in Medical Literature
Study Purpose The purpose of the BeneMACS Long-Term LVAD Study is to demonstrate that survival in non transplant patients implanted with the HeartMate II LVAD as destination therapy in Belgium and the Netherlands are equivalent…
- Trial name
- BeneMACs (NCT00983190)
- Testing
- Left Ventricular Assist Device (HeartMate II)
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Abbott Medical Devices
Prevention & Control
Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
The primary objectives of this study are: To determine whether rivaroxaban 2.5 mg twice daily (bid) + aspirin 100 mg once daily (od) compared with aspirin 100 mg od reduces the risk of a composite of myocardial infarction…
- Trial name
- COMPASS (NCT01776424)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Aspirin, Pantoprazole
- Where
- 565 sites in United States, Argentina and 31 more
- Volunteers
- 27,395 people
- Sponsor
- Bayer
Coronary Disease, Coronary Stenosis
A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease
The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in…
- Trial name
- FAME 3 (NCT02100722)
- Testing
- FFR guided PCI, CABG, Resolute Integrity Stent
- Where
- 46 sites in United States, Australia and 14 more
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Thrombocytopenia, Thrombosis
Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)
The purpose of this study is to examine the safety and efficacy of Angiomax as an anticoagulation in patients with heparin-induced thrombocytopenia (HIT)/heparin-induced thrombocytopenia with thrombosis syndrome (HITTS)…
- Conditions
- Thrombocytopenia, Thrombosis, Cardiac Disease, Coronary Artery Bypass Surgery
- Trial name
- NCT00073580
- Testing
- Angiomax (bivalirudin) anticoagulant
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- The Medicines Company
Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion
PAC-IC-SAOS Obstructive Sleep Apnea Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of obstructive sleep apnea syndrome (OSAS) treatment in heart failure patients following coronary artery bypass graft (CABG) surgery or other coronary reperfusion.
- Conditions
- Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion, Sleep Apnea, Obstructive
- Trial name
- PAC-IC-SAOS (NCT01900379)
- Testing
- CPAP treatment
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Grenoble