Coronary Artery Bypass Graft SurgeryNCT07006441

Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery

A study testing Preoperative Cardiac Rehabilitation and Postoperative Cardiac Rehabilitation in people with Coronary Artery Bypass Graft Surgery and Coronary Artery Disease, run by Atlas University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function, peripheral muscle strength, pain, kinesiophobia, and quality of life in patients undergoing… Read more about this study

Who is it for?: Ages 18 to 65 years
Conditions the study is for: Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
What is being tested?: Preoperative Cardiac Rehabilitation and Postoperative Cardiac Rehabilitation
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 30 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 1 Aug 2024to 1 Aug 2025
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 65 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Having undergone coronary artery bypass graft surgery
Ejection Fraction (EF) > 40%
Being between the ages of 18-65
Being able to speak, read and understand in their own language
Volunteering to participate in the study

Who cannot join

Having an active or suspected infection
Presence of an active tumour
History of thrombophlebitis or pulmonary embolism within the last 3 months
Having an orthopaedic, neurological or cardiovascular disease that may affect the assessments

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Istanbul Atlas University
Istanbul

Other trials in Turkey (Türkiye)

About this study

Official title: The Effects of Preoperative and Postoperative Cardiac Rehabilitation in Patients Undergoing Coronary Artery Bypass Graft Surgery

Conditions: Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
Being tested: Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
Keywords: Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
Medical subject headings: Coronary Artery Disease

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Preoperative Cardiac RehabilitationOther
Structured exercise program, respiratory physiotherapy, and patient education
Postoperative Cardiac RehabilitationOther
Structured exercise program, respiratory physiotherapy, and patient education

Study groups in NCT07006441
Study group	Role	What they receive
Experimental Group	Experimental	Preoperative cardiac rehabilitation + postoperative cardiac rehabilitation (structured exercise, respiratory physiotherapy, and patient education) Receives: Other: Preoperative Cardiac Rehabilitation; Other: Postoperative Cardiac Rehabilitation
Control Group	Active comparator	Postoperative cardiac rehabilitation (structured exercise, respiratory physiotherapy, and patient education) Receives: Other: Postoperative Cardiac Rehabilitation

What is being measured

The primary outcome is the main question the study is designed to answer.

Forced Vital Capacity (FVC)
Forced Vital Capacity will be measured before six-minute walk test according to the guideline of ERS.
Measured: 2 weeks
Forced Expiratory Volume in 1 second (FEV1)
Forced Expiratory Volume in 1 second will be measured before six-minute walk test according to the guideline of ERS.
Measured: 2 weeks
Peak Expiratory Flow (PEF)
Peak Expiratory Flow will be measured before six-minute walk test according to the guideline of ERS.
Measured: 2 weeks
Forced Expiratory Flow 25-75% (FEF25-75)
Forced Expiratory Flow 25-75% will be measured before six-minute walk test according to the guideline of ERS.
Measured: 2 weeks
6-minute Walk Test
The 6-minute Walk Test will be performed according to ATS guidelines. Walking distance, minute ventilation, respiratory rate, inspiratory capacity and breathing reserve will be recorded.
Measured: 2 weeks
M. Quadriceps Muscle Strength
The m. quadriceps muscle strength will be measured using the MicroFet 2 hand-held dynamometer (Hogan Health Industries, USA). The test will be repeated three times for the dominant side and the average value in kilograms (kg) will be recorded.
Measured: 2 weeks
M. Biceps Muscle Strength
The m. biceps muscle strength will be measured using the MicroFet 2 hand-held dynamometer (Hogan Health Industries, USA). The test will be repeated three times for the dominant side and the average value in kilograms (kg) will be recorded.
Measured: 2 weeks
Cough Peak Flow
Cough Peak Flow (CPF) will be measured using a peak expiratory flow meter. Participants will be instructed to take a maximal deep breath and then cough as forcefully as possible into the device; the highest value from three trials will be recorded in liters per minute (L/min). Measurements will be performed in a seated position, ensuring a tight mouth seal and consistent technique.
Measured: 2 weeks

Secondary outcomes (3)

Level of Pain
Pain assessment will be performed using the Visual Analog Scale (VAS) to evaluate chest pain levels. Participants will be asked to mark their current pain intensity on a 10 cm horizontal line, with "no pain" at one end and "worst imaginable pain" at the other. The distance in centimeters from the "no pain" end to the mark will be measured and recorded as the pain score.
Measured: 2 weeks
Level of Fear of Movement
Fear of movement (kinesiophobia) will be assessed using the Tampa Scale for Kinesiophobia (TSK). Participants will complete the 17-item questionnaire, which evaluates fear of movement and re-injury on a 4-point Likert scale. The total score, ranging from 17 to 68, will be calculated, with higher scores indicating greater fear of movement.
Measured: 2 weeks
Level of Quality of Life
Quality of life will be assessed using the Short Form-36 (SF-36) Health Survey. Participants will complete the 36-item questionnaire, which evaluates eight domains including physical functioning, bodily pain, general health, and mental well-being. Each domain will be scored from 0 to 100, with higher scores indicating better perceived quality of life.
Measured: 2 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Aug 20241 Aug 2025

First posted5 Jun 2025
Study start1 Aug 2024
Primary completion1 Aug 2025
Study completion1 Aug 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Coronary Artery Bypass Graft SurgeryStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Model description: Randomized, Parallel Assignment
Masking: Single blind
Who is masked: Participant
Enrolment: 30 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07006441
Sponsor's protocol ID: auhucgun04
Status last verified: Aug 2025
First submitted: 28 May 2025
Last updated: 27 Aug 2025
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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