Clinical trials: Health Adult Subjects, open to volunteers
Healthy Adult Participants, Gut Health
Exploration of Tolerability and Dose Responses for a Yeast-based Probiotic
The purpose of this study is to evaluate the tolerability and efficacy of a yeast-based dietary supplement on gastrointestinal, mental, and skin health.
- Trial name
- NCT07867496
- Testing
- 9.9 x 10^7 Pichia kluyveri PK88, 1 x 10^8 Pichia kluyveri PK88
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Health Adult Subjects
Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX29 Compared With HLX11
This is a randomized, double-blind, parallel-controlled study to compare the PK profile of HLX29 and HLX11 and evaluate their safety, tolerability, and immunogenicity after a single intravenous dose in healthy male adult…
- Trial name
- NCT07776132
- Testing
- HLX29, HLX11
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Henlius Biotech
Circadian Rhythm, Health Adult Subjects
Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise
This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals…
- Trial name
- NCT07833956
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Gut Health, Gastrointestinal Symptoms
IgG Binding Protein LT in Support of a Healthy Gut on the Go
PS52 is a randomized, double-blind, placebo-controlled, fully decentralized study sponsored by Bactolife A/S and conducted by People Science, Inc.
- Conditions
- Gut Health, Gastrointestinal Symptoms, Safety in Healthy Adults
- Trial name
- NCT07873957
- Testing
- IgG Binding Protein LT
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Older Adults, Nursing Homes
Technology Use, Safe Health Information, and Artificial Intelligence Among Older Adults
Objective The aim of this research is to evaluate how improving the technology use skills of older adults in nursing homes changes their perceptions of access to safe health information and the use of artificial intelligence.
- Conditions
- Older Adults, Nursing Homes, Artifical Intelligence, Technology Use
- Trial name
- NCT07881614
- Testing
- E-Health Literacy Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ondokuz Mayıs University
Health Adults
Sodium Bicarbonate Solution Enhances Lens Cleanliness in Magnetically Controlled Capsule Endoscopy
Magnetically controlled capsule endoscopy (MCE) is a noninvasive alternative to conventional gastroscopy with comparable diagnostic accuracy.
- Trial name
- NCT07877506
- Testing
- Sodium Bicarbonate Solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Chronic Insomnia, Older Adults
Brief Behavioral Therapy for Insomnia (BBTi) in Middle-aged and Older Adults With Chronic Insomnia
This study aims to investigate whether a nurse-led brief behavioral therapy can effectively improve chronic insomnia and sleep health in older adults.
- Conditions
- Chronic Insomnia, Older Adults, Sleep Hygiene, Sleep Health
- Trial name
- NCT06073990
- Testing
- Brief Behavioral Treatment for Insomnia (BBTi)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Cheng-Kung University Hospital
Type 2 Diabetes Mellitus, Health Adult Subjects
Sleep Quality, Adiposity and Diet Quality
The aim of this study is to evaluate the effects of sleep quality on cardiovascular disease risk and food and nutrient intakes. Within the scope of this study, several parameters associated with cardiovascular disease risk will…
- Trial name
- Obesity (NCT07870122)
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Health Adults
Prenatal Androgen and Skills
Due to the difficulties and risks of directly measuring prenatal hormone levels, biomarkers that indirectly reflect this exposure are used in research.
- Trial name
- NCT07627113
- Testing
- Digit Ratio, Fine motor skills, Tactile Discrimination
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs)
Impact of Pharmacotherapy Optimization in Polymedicated Lebanese Older Adults in Primary Health Care Centers
Why are the researchers doing this study? Many older adults take five or more medicines every day. Some of these medicines may no longer help them. Some may even cause harm, such as falls, confusion or tiredness.
- Conditions
- Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs), Primary Health Care, Social Determinants of Health (SDOH)
- Trial name
- PHARMACT-PHC (NCT07866677)
- Testing
- Structured pharmacotherapy optimization, Usual Care
- Where
- Lebanon
- Volunteers
- 452 people
- Sponsor
- National Institute of Public Health, Clinical Epidemiology, and Toxicology-Lebanon (INSPECT-LB)
Health Adult Subjects, Obesity & Overweight
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
Randomized, Placebo-controlled Study to determine the safety and tolerability of multiple oral doses of TIX100 administered daily for 28 days to otherwise healthy overweight/obese subjects.
- Trial name
- NCT07675590
- Testing
- TIX100
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- TIXiMED, Inc.
PARKINSON DISEASE (Disorder), Health Adult Subjects
Balance Performance and Quality of Life in Parkinson's Disease
This observational study aims to examine the relationship between performance-based balance test results and quality of life in individuals with Parkinson's disease.
- Trial name
- NCT07833150
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Health Adult Subjects
Effect of Different Currents for Transcranial Modulation of the Sensorimotor Corticospinal Pathway in Healthy Subjects
Transcranial modulation of the corticospinal sensorimotor pathway is a promising approach in neuroscientic functions. Among the techniques used, transcranial direct current stimulation (tDCS), transcranial alternating current…
- Trial name
- CURRENT-Flow (NCT07831525)
- Testing
- Transcranial Alternating Current Stimulation, Transcranial Direct Current Stimulation, Transcranial Random Noise Stimulation (tRNS)
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Walking, Older Adults (65 Years and Older)
Promoting Walking Among Older Adults Through Affective Communication and Step-Monitoring
Physical inactivity increases substantially after age 60 and represents a major public health challenge in older adults, as it is linked to increased risk of functional and cognitive decline and aging problems.
- Conditions
- Walking, Older Adults (65 Years and Older), Messaging, Mobile Applications
- Trial name
- NOSTEP (NCT07570303)
- Testing
- Self-continuity prompts, Step-monitoring reminders, Water intake messages
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Catholic University, Italy
Health Adult Subjects, Moderate-to-Severe Atopic Dermatitis
A Phase I Study of HXN5003 in Healthy Participants and Patients With Moderate-to-Severe Atopic Dermatitis
This is a Phase I, multicenter, randomized, double-blind, placebo-controlled study evaluating HXN5003 in healthy participants and patients with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT07801612
- Testing
- HXN5003
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Helixon Biotechnology (Suzhou) Co., Ltd
Older Adults, Medication and Supplement Use
Senior Center Medication Safety and Empowerment Curriculum
Team Alice's Medication Safety and Empowerment Curriculum (MedSEC) helps older adults and caregivers learn how to safely manage medications.
- Conditions
- Older Adults, Medication and Supplement Use, Caregiver Awareness, Health Literacy
- Trial name
- NCT07799610
- Testing
- Team Alice Medication Safety and Empowerment Curriculum (MedSEC)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- State University of New York at Buffalo
Musculoskeletal Health, Healthy Adult Volunteers
The Effects of the Yi Jin Jing on the Muscles and Bones of Adults
Observation of the effects of Yi Jin Jing on the muscles and bones of adults
- Trial name
- NCT07753291
- Testing
- Yijinjing
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Youth Mental Health, Psychological Distress in Adolescents and Young Adults
VIPeerAgent for Adolescent Mental Health
This three-arm parallel randomized controlled trial aims to evaluate the effectiveness of VIPeerAgent, a virtual peer support agent, in improving mental health outcomes among adolescents and young adults aged 14-25 years…
- Conditions
- Youth Mental Health, Psychological Distress in Adolescents and Young Adults, Early Intervention
- Trial name
- NCT07778758
- Testing
- Virtual Peer Agent Intervention, Human peer mentor
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Yat-sen University
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Health Adult Subjects, Atopic Dermatitis (AD)
Study of HXN6005 in Healthy Participants and Patients With Moderate-to-Severe Atopic Dermatitis
This is a Phase I/II, multicenter, randomized, double-blind, placebo-controlled study evaluating HXN6005 in healthy participants and patients with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT07782476
- Testing
- HXN6005
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Helixon Biotechnology (Suzhou) Co., Ltd