Musculoskeletal HealthNCT07753291
The Effects of the Yi Jin Jing on the Muscles and Bones of Adults
A study testing Yijinjing in people with Musculoskeletal Health and Healthy Adult Volunteers, run by Beijing Hospital of Traditional Chinese Medicine at 1 site in China.
Trial summary
Observation of the effects of Yi Jin Jing on the muscles and bones of adults Read more about this study
- Who is it for?
- Ages 18 to 90 yearsHealthy volunteers can take part
- Conditions the study is for
- Musculoskeletal Health, Healthy Adult Volunteers
- What is being tested?
- Yijinjing
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteChina
- Study dates
- 1 Sep 2026to 31 Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 90 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Age 18-90 years inclusive;
- Generally healthy, no acute or chronic diseases affecting major organ functions;
- No cognitive impairment, able to understand and comply with study procedures;
- Willing and able to provide written informed consent;
- No pregnancy or lactation (for females);
- No recent (within 3 months) major surgery, hospitalization, or significant weight change (>5% body weight).
Who cannot join
- Presence of acute or unstable chronic diseases (e.g., uncontrolled hypertension, diabetes, heart failure, or malignancy);
- Severe cognitive impairment, psychiatric disorders, or inability to follow study instructions;
- Recent (≤3 months) major surgery, trauma, or hospitalization;
- Pregnancy, lactation, or childbearing potential without reliable contraception;
- Body mass index (BMI) <16 or >40 kg/m²;
- Current use of medications affecting muscle or nutritional metabolism (e.g., corticosteroids, anabolic steroids);
- Participation in another interventional trial within 30 days.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
No. 23, Ganju Road, Dongcheng District, Beijing
Beijing
Jin He, 17600765734, 17600765734@163.com
About this study
Observation of the effects of Yi Jin Jing on the muscles and bones of adults
- Conditions
- Musculoskeletal Health, Healthy Adult Volunteers
- Being tested
- Yijinjing
- Keywords
- Yijinjing, Healthy Adult Volunteers, Musculoskeletal Health
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
YijinjingBehavioural
Yijinjing
| Study group | Role | What they receive |
|---|---|---|
| The effects of Yi Jin Jing on the muscles and bones of adults | Experimental | Yijinjing exercise Receives: Behavioral: Yijinjing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Appendicular Skeletal Muscle Index
Appendicular Skeletal Muscle Index (ASMI) = appendicular lean mass (kg) / height² (m²). It reflects muscle mass, used for sarcopenia diagnosis. Lower values indicate muscle loss, linked to aging, malnutrition, or disease.
Measured: Day 180 ± 10 days
Secondary outcomes (6)
Handgrip strength
Handgrip strength (HGS) = maximum force (kg) measured by a dynamometer. It reflects overall muscle function, predicts disability, morbidity, and mortality. Low HGS indicates sarcopenia, frailty, or poor nutritional status.
Measured: Day 180 ± 10 days
Nutrition intake form（MNA）
Mini Nutritional Assessment - Short Form (MNA-SF) consists of 6 items:
- Appetite and food intake - assesses whether food intake has decreased over the past 3 months.
- Weight loss - records recent unintentional weight loss.
- Mobility - determines whether the person can walk independently or is bedridden.
- Acute disease or psychological stress - checks for stressful events in the past 3 months.
- Neuropsychological problems - identifies dementia, depression, or other mental disorders that affect eating.
- Body mass index (BMI) or calf circumference - reflects body fat reserves and muscle mass.
Each item scores 0-3 points. A total score ≤11 indicates a risk of malnutrition. It is commonly used for nutritional screening in elderly populations.
Measured: Day 180 ± 10 days
Fried
Fried Frailty Phenotype = a 5-item scale assessing unintentional weight loss, exhaustion, low grip strength, slow walking speed, and low physical activity. item ≥3 = frail; 1-2 = prefrail; 0 = robust. Predicts falls, disability, and mortality.
Measured: Day 180 ± 10 days
FRAIL
FRAIL Scale = a 5-item questionnaire: Fatigue, Resistance (climb stairs), Ambulation (walk), Illness (≥5 chronic conditions), and Loss of weight (≥5%). Score 0 = robust, 1-2 = prefrail, 3-5 = frail. Quick screening for frailty in community settings.
Measured: Day 180 ± 10 days
SPPB
Short Physical Performance Battery (SPPB) = a 3-component test: standing balance (0-4), 4-meter gait speed (0-4), and 5-repetition chair stand (0-4). Total score 0-12; ≤8 indicates poor physical function, predicts disability, falls, and mortality in older adults.
Measured: Day 180 ± 10 days
Muscle mass measured by ultrasound
Ultrasound-based measurements of peripheral skeletal muscles offer a practical, non-invasive, and radiation-free approach for assessing muscle mass in clinical and research settings. In accordance with previously established cut-off values, the following parameters are employed to identify a tendency toward reduced muscle mass:
- Biceps brachii cross-sectional area (CSA) - a male-specific indicator, with a value < 7.1 cm² suggesting reduced muscle mass;
- Tibialis anterior muscle thickness (MT) - a female-specific indicator, with a value < 2.3 cm suggesting reduced muscle mass;
- Rectus femoris muscle thickness (MT) - a gender-neutral rapid screening index, with a value < 1.3 cm serving as a universal cut-off for both men and women, indicating a tendency toward low muscle mass.
These ultrasonographic parameters are intended for initial screening and may assist in the early identification of individuals at risk for sarcopenia, particularly when access to dual-energy X-ray abs
Measured: Day 180 ± 10 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Aug 2026
- Study start1 Sep 2026 (estimated)
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Musculoskeletal HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Beijing Hospital of Traditional Chinese Medicine
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, He Jin, Beijing Hospital of Traditional Chinese Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07753291
- Sponsor's protocol ID
- 2025BL02-161-02
- Status last verified
- Aug 2026
- First submitted
- 4 Aug 2026
- Last updated
- 1 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 1 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of the Yi Jin Jing on the Muscles and Bones of Adults
- ClinicalTrials.gov ID
- NCT07753291
- Acronym / sponsor ID
- 2025BL02-161-02
- Conditions
- Musculoskeletal Health, Healthy Adult Volunteers
- Keywords
- Yijinjing, Healthy Adult Volunteers, Musculoskeletal Health
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Beijing Hospital of Traditional Chinese MedicineUniversity, hospital or other
- Study start
- 1 Sep 2026 (estimated)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 7 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Observation of the effects of Yi Jin Jing on the muscles and bones of adults
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| The effects of Yi Jin Jing on the muscles and bones of adults | Experimental | Behavioral: YijinjingYijinjing exercise |
Who may qualify
- Ages
- 18 to 90 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age 18-90 years inclusive;
- Generally healthy, no acute or chronic diseases affecting major organ functions;
- No cognitive impairment, able to understand and comply with study procedures;
- Willing and able to provide written informed consent;
- No pregnancy or lactation (for females);
Key exclusion criteria (7 listed)
- Presence of acute or unstable chronic diseases (e.g., uncontrolled hypertension, diabetes, heart failure, or malignancy);
- Severe cognitive impairment, psychiatric disorders, or inability to follow study instructions;
- Recent (≤3 months) major surgery, trauma, or hospitalization;
- Pregnancy, lactation, or childbearing potential without reliable contraception;
- Body mass index (BMI) <16 or >40 kg/m²;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| YijinjingYijinjing | Behavioural | The effects of Yi Jin Jing on the muscles and bones of adults |
Primary outcome
Appendicular Skeletal Muscle Index
Time frame: Day 180 ± 10 days
Appendicular Skeletal Muscle Index (ASMI) = appendicular lean mass (kg) / height² (m²). It reflects muscle mass, used for sarcopenia diagnosis. Lower values indicate muscle loss, linked to aging, malnutrition, or disease.
6 secondary outcomes
Handgrip strength
Time frame: Day 180 ± 10 days
Nutrition intake form（MNA）
Time frame: Day 180 ± 10 days
Fried
Time frame: Day 180 ± 10 days
FRAIL
Time frame: Day 180 ± 10 days
SPPB
Time frame: Day 180 ± 10 days
Muscle mass measured by ultrasound
Time frame: Day 180 ± 10 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Yijinjing in people with Musculoskeletal Health and Healthy Adult Volunteers, run by Beijing Hospital of Traditional Chinese Medicine at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 1 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact jin he hejin (+8617600765734, 17600765734@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Appendicular Skeletal Muscle Index (time frame: Day 180 ± 10 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Sep 2026.