Clinical trials: Healing Wound
Anterior Vaginal Wall Prolapse, Pelvic Organ Prolapse
Transobturator Lateral Suspension in Anterior Colporrhaphy
Anterior colporrhaphy (AC) is commonly used for anterior vaginal wall prolapse, but suffers high recurrence rates. This randomized trial assessed whether adding transobturator lateral suspension (TOLS) to AC decreases objective…
- Trial name
- TLSAC (NCT07144397)
- Testing
- TOLS
- Where
- Slovenia
- Volunteers
- 44 people
- Sponsor
- University Medical Centre Maribor
DMMR Cancer, MSI-H
Registry Study in MSI/dMMR Solid Tumors
This study is a multi-center, non-interventional, prospective clinical observational study, aiming to evaluate the effectiveness and safety of subsequent treatment in dMMR/MSI solid tumor patients who have never received ICIs…
- Conditions
- DMMR Cancer, MSI-H, Solid Tumor
- Trial name
- NCT06004713
- Where
- 10 sites in China
- Volunteers
- 190 people
- Sponsor
- Peking University Cancer Hospital & Institute
Diabetic Foot
The Association Between Unprotected Standing, Walking and Wound Healing in Diabetes
The aim of the study was to explore the association between activities of daily living ( measured using a body-worn sensor) on wound healing in diabetic patients. Since this was an exploratory study, there was no study hypothesis.
- Trial name
- NCT02233179
- Testing
- Removable cast walker, Irremovable cast walker
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Arizona
Wound Heal
The Effect of Donepezil on Wound Healing
The purpose of the study is to test effectiveness of donepezil to improve wound healing in patients with diabetic wounds that have not healed with standard treatment.
- Trial name
- NCT04505670
- Testing
- Donepezil, Topical Zinc Oxide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Abdominal Disorder
Evaluation of Laparoscopic Cholecystectomy and Concomitant Paraumbilical Hernia Repair
Umbilical hernia frequently accompanies cholelithiasis. It is possible to repair these hernias after completing cholecystectomy.
- Trial name
- NCT06317779
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Wound - in Medical Care
Wound Assessment Accuracy and Treatment Efficiency
Wound assessment is critical for developing effective treatment strategies, yet there is a scarcity of research on the assessment accuracy of clinical practitioners.
- Trial name
- NCT07261488
- Where
- China
- Volunteers
- 553 people
- Sponsor
- Peking University Third Hospital
Venous Leg Ulcers, Venous Leg Ulcers (VLUs)
Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs
The purpose of this study is to evaluate the efficacy of two dehydrated human umbilical cord-based medical devices, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in…
- Conditions
- Venous Leg Ulcers, Venous Leg Ulcers (VLUs), Venous Leg, Leg Ulcers
- Trial name
- CORDSTIM-VLU (NCT07449988)
- Testing
- Standard of Care (SOC), Corplex P, Theracor
- Volunteers
- 272 people
- Sponsor
- StimLabs
Wound of Knee, Wound of Hip
Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery
The aim of this study is to assess the prevention of incision healing complications in patients undergoing Total Knee Arthroscopy (TKA) and Total Hip Arthroscopy (THA) treated with either Single-Use Incisional NPWT (Negative…
- Trial name
- PICO (NCT02064270)
- Testing
- Single-Use Negative Pressure Wound Therapy, Standard postsurgical dressings
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- University of Missouri-Columbia
Heart Failure With Reduced Ejection Fraction
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
This clinical trial investigates the safety and preliminary effectiveness of YAP101, a gene therapy designed to improve heart function in adults with ischemic heart failure and reduced ejection fraction (HFrEF).
- Trial name
- SALVADOR-HF (NCT06831825)
- Testing
- YAP101 (AAV9-Sav-shRNA)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medley Therapeutics
Ventral Hernia Repair
Robotic Minimally Invasive Ventral Hernia Repair With DEXTER
The aim of this clinical investigation is to confirm the perioperative and early postoperative safety and clinical performance (efficacy) of the Dexter Robotic System, in patients undergoing incisional or primary ventral hernia…
- Trial name
- RAVEN (NCT07071740)
- Testing
- ventral hernia repair
- Where
- 5 sites in Austria, France and 2 more
- Volunteers
- 33 people
- Sponsor
- Distalmotion SA
Microcirculation, Wound Healing
Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?
This study aims to test the hypothesis that postoperative daily hyperbaric oxygen therapy (HBOT) decreases soft-tissue complication rate during the operative handling of intra-articular calcaneal fractures. Minor motivations: 1.
- Trial name
- HOCIF (NCT01264146)
- Testing
- HBOT
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Congenital Disorders
Comparison of NIRS and Serum Lactate to Predict Poor Post-operative Outcomes
Mortality after neonatal cardiac repair remains significant, and neonates who have undergone operative repair of congenital heart disease may experience sudden and unexpected demise.
- Trial name
- NCT00485524
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Healthcare of Atlanta
Surgical Training
Study of Fast-track Surgery in Hernia Repair and Laparoscopic Cholecystectomy
All Danish trainees in surgery in a two-year period asked for participation when enrolled in the formal five-year training program for specialty in surgery.
- Trial name
- NCT01877824
- Testing
- Fast-track training
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Aarhus
Narcotic Consumption, Pain
Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures
This study will compares differences in pain level, narcotic consumption, wound healing, patient satisfaction in patients randomized to the Iceman® cold pack therapy system (djOrtho, Inc) versus those who use ice.
- Conditions
- Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
- Trial name
- NCT00950183
- Testing
- Iceman® Cold Therapy unit (djOrtho), Ice
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Inguinal Hernia
Effect of Inguinal Hernia Repair on Isokinetic Muscle Strength
The aim of the present prospective controlled study is to compare the trunk muscle strength, quality of life and neuropathic pain component after Lichtenstein and Kugel procedures.
- Trial name
- NCT02871583
- Testing
- lichtenstein, Kugel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Fanconi Anemia
FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector
This is a Phase I/II clinical trial of gene therapy for treating Fanconi anemia using a self-inactivating lentiviral vector to functionally correct the defective gene.
- Trial name
- NCT03351868
- Testing
- Gene-modified autologous stem cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Ataxia Telangiectasia
Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects
A Randomized, Open-label, Crossover Study to Evaluate the Comparative Bioavailability, Pharmacokinetics, and Safety of GTX-102 Administered as an Oral Spray Compared to Intramuscular Injection - betamethasone and an Oral Solution…
- Trial name
- NCT05531890
- Testing
- GTX-102 medium dose fast Period 1 and Period 2, GTX-102 medium dose slow Period 1 and Period 2, GTX-102 high dose fast Period 1 and Period 2
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grace Therapeutics Inc.
Shoulder Dislocation
The Effect of Arthroscopic Bankart Repair on Anterior-posterior Glenohumeral Translation and Shoulder Proprioception in Patients With Traumatic Anterior Shoulder Instability: a Prospective Cohort Study
The purpose of the study is to investigate biomechanical and proprioceptive conditions in patients with symptomatic traumatic anterior shoulder instability undergoing arthroscopic Bankart repair.
- Trial name
- NCT05250388
- Testing
- Arthroscopic Bankart repair
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Catarina Malmberg
Cesarean Section
Aloe Vera on Caesarean Section Wound
Conducting clinical research in line with the literature recommendation, with a method that is low-cost, accessible, easy-to-use, and examined in an evidence-based design related to cesarean section wound, which negatively…
- Trial name
- NCT05223127
- Testing
- Aloe vera
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Pancreas Cancer, Pancreatitis
Pancreas Registry and High Risk Registry
The purpose of this study is to establish a registry of patients with pancreatic diseases. Patients included in the registry may include those with: pancreatic cancer, precancerous lesions of the pancreas, inflammatory lesions of…
- Conditions
- Pancreas Cancer, Pancreatitis, Chronic Pancreatitis, Pancreatic Cyst
- Trial name
- NCT02775461
- Where
- 2 sites in United States
- Volunteers
- 1,368 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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