Clinical trials: Hand Therapy
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema
The purpose of this trial is to test if delgocitinib cream is effective in treating chronic hand eczema (CHE) and to find out what side effects it may have compared with a cream vehicle with no active medical ingredient in…
- Trial name
- DELTA TEEN (NCT05355818)
- Testing
- Delgocitinib, Cream vehicle
- Where
- 37 sites in Australia, Belgium and 5 more
- Volunteers
- 98 people
- Sponsor
- LEO Pharma
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Stroke, Acute, Stroke
Treatments for Recovery of Hand Function in Acute Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.
- Conditions
- Stroke, Acute, Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00565045
- Testing
- Neuromuscular electrical stimulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- MetroHealth Medical Center
Thumb Carpometacarpal Joint Osteoarthritis
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint.
- Trial name
- NCT00685880
- Testing
- Prolotherapy (10% dextrose solution), Betamethasone
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
ACTINIC KERATOSES
Photodynamic Therapy With Levulan® +/- Topical Retinoid Pre-Treatment In The Treatment Of Actinic Keratoses
To determine and compare the safety and efficacy of broad area photodynamic therapy with aminolevulinic acid (ALA-PDT) following topical retinoid pre-treatment vs ALA-PDT with occlusion only (no pretreatment) in subjects with…
- Trial name
- NCT01053000
- Testing
- Tazorac
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stewart, Roger H., M.D., P.A.
Spinal Cord Injuries
Efficacy Study of the Music Glove Patients With Spinal Cord Injuries
Investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to patients with spinal cord injuries. All participants will be randomized into two groups: AB and BA.
- Trial name
- NCT02473614
- Testing
- Music Glove, Conventional Hand Exercise Program
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Irvine
Isolated Focal Hand Dystonia
Neuromodulation Therapy for Task-Specific Dystonia
This study aims to apply a non-invasive brain stimulation technology called repetitive Transcranial Magnetic Stimulation (rTMS) in patients with focal hand dystonia (FHD).
- Trial name
- NCT06422104
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke, Physical Disability
Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke
More than 4 million stroke survivors in the U.S. suffer from post-stroke sensorimotor hand disability, which is typically permanent and difficult to treat.
- Trial name
- NCT04026399
- Testing
- peripheral vibration stimulation, therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Chronic Hand Eczema
Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
The purpose of this research trial was to test different strengths of a new trial medication, delgocitinib cream 1, 3, 8, and 20 mg/g, and to investigate how treatment with delgocitinib cream affects chronic hand eczema.
- Trial name
- NCT03683719
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- 28 sites in United States, Denmark and 1 more
- Volunteers
- 258 people
- Sponsor
- LEO Pharma
Focal Dystonia
rTMS and Retraining in Focal Hand Dystonia
This study is exploring a new experimental procedure in dystonia called repetitive transcranial magnetic brain stimulation (TMS) combined with rehabilitation.
- Trial name
- DSS (NCT01738581)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Osteoarthrosis
Efficacy Study of Condrosulf in the Treatment of Symptomatic OA of the Hand
The goal of the present study is to investigate the effectiveness of Condrosulf® 800 mg tablets vs. placebo once a day for 6 months in the symptomatic treatment of finger joint osteoarthritis.
- Trial name
- NCT00291499
- Testing
- Chondroitin 4&6 sulfate (Condrosulf)
- Volunteers
- 163 people
- Sponsor
- IBSA Institut Biochimique SA
Primary Focal Hyperhidrosis of the Hands
BTX-A Treatment for Palmar Hyperhidrosis
Primary focal hyperhidrosis (excessive sweating) is a debilitating condition affecting approximately 3% of the population in the United States.
- Trial name
- NCT01262339
- Testing
- BTX-A
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Cerebral Palsy
Robotic-assisted Therapy to Improve Manual Dexterity in Children With Cerebral Palsy
This is an intervention study including a baseline data collection, 6 weeks of robot-assisted training targeting hand dexterity, and a post-intervention data collection.
- Trial name
- NCT02923167
- Testing
- Robotic-assisted training of the hand
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Spaulding Rehabilitation Hospital
Cerebral Palsy, Hemiplegia
Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with…
- Conditions
- Cerebral Palsy, Hemiplegia, Children, Pediatric
- Trial name
- NCT00305006
- Testing
- Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Teachers College, Columbia University
Stroke
Robot-Assisted Hand Motor Therapy for Subjects With Hemiparetic Stroke
The purpose of this study is to develop and assess the effectiveness of robot-assisted movement therapy in enhancing hand motor function in subjects with chronic hemiparetic stroke, and to identify predictors of treatment…
- Trial name
- Robot3 (NCT01244243)
- Testing
- Hand & Wrist Assisting Robotic Device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Irvine
Cerebral Palsy Spastic Hemiplegic
Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
This study evaluates the therapeutic effects of constraint-induced movement therapy on infants and children with hemiplegic cerebral palsy.
- Trial name
- NCT03858335
- Testing
- Constraint-induced movement therapy
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Stroke, Physical Disability
Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.
- Trial name
- NCT04569123
- Testing
- real stimulation, No stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Medical University of South Carolina
Hand Osteoarthritis
RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
This is a randomized, double blind placebo controlled one-site proof-of-concept study in subjects with erosive osteoarthritis (OA) of interphalangeal (IP) finger joints.
- Trial name
- NCT02771860
- Testing
- denosumab, Calcium/Vit D supplementation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
DeQuervains Tenosynovitis, Lateral Epicondylitis
Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders
The primary objective of this study is to compare local corticosteroid hand and elbow injections to placebo or ketorolac to determine if there is an equal or better reduction of symptoms for common orthopaedic upper extremity…
- Conditions
- DeQuervains Tenosynovitis, Lateral Epicondylitis, Tennis Elbow, Trigger Finger
- Trial name
- NCT02266433
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- NYU Langone Health
Hand Osteoarthritis
Efficacy of Shinabro in Hand Osteoarthritis
GCSB-5 ("Shinbaro capsule"), is a mixture of 6 oriental herbs that have anti-inflammatory and analgesic effects along with an excellent safety profile.
- Trial name
- NCT01910116
- Testing
- Shinbaro
- Where
- 3 sites in South Korea
- Volunteers
- 220 people
- Sponsor
- Seoul National University Hospital