Clinical trials: Hand Therapy
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema
The purpose of this trial is to test if delgocitinib cream is effective in treating chronic hand eczema (CHE) and to find out what side effects it may have compared with a cream vehicle with no active medical ingredient in…
- Trial name
- DELTA TEEN (NCT05355818)
- Testing
- Delgocitinib, Cream vehicle
- Where
- 37 sites in Australia, Belgium and 5 more
- Volunteers
- 98 people
- Sponsor
- LEO Pharma
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Chronic Hand Dermatitis
Apremilast and Moderate to Severe Chronic Hand Dermatitis
Investigators have designed a pilot study involving chronic hand dermatitis (CHD) patients who attend the dermatology clinic at the George Washington Medical Faculty Associates (GW MFA) in order to assess the efficacy and safety…
- Trial name
- CHD (NCT03741933)
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- George Washington University
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Hand Osteoarthritis
Pulsed Radiofrequency Therapy for Hand OsteoArthritis Pain
Different types of pain may be present in patients with hand osteoarthritis, including nociceptive pain and non-nociceptive pain. This makes adequate pain treatment difficult, and thus new treatment options are needed.
- Trial name
- PROAP (NCT05217979)
- Testing
- Transcutaneous pulsed radiofrequency
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Carpometacarpal; Dislocation
Carpometacarpal Fracture-dislocations
Fracture-dislocation of the carpometacarpal (CMC) joints of the ring and little finger are the most affected CMC joints and the dislocation may be accompanied by other hand injuries.
- Trial name
- Dislocation (NCT04668794)
- Testing
- Osteosynthesis
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gross Motor Development Delay, Cerebral Palsy
Small Step Intervention for Infants With Cerebral Palsy and Other Neurodevelopmental Disorders
Children with cerebral palsy (CP) have life-long motor disorders and are typically subjected to extensive treatment throughout childhood.
- Trial name
- smallstep (NCT02166801)
- Testing
- Early intervention for infants, usual care
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Karolinska Institutet
Stroke
MTPr With Shockwave on Pain & Function of SHS in Stroke
Background: shoulder-hand syndrome is considered a significant reason for the reduction of upper limb functions after stroke. Purpose: To investigate the influence of Myofascial Trigger Points (MTrPs) release and shockwave…
- Trial name
- NCT04627636
- Testing
- Myofascial trigger points pressure (MTrP) release, Shockwave therapy application, conventional therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Stroke, Acute, Stroke
Treatments for Recovery of Hand Function in Acute Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.
- Conditions
- Stroke, Acute, Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00565045
- Testing
- Neuromuscular electrical stimulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- MetroHealth Medical Center
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Fingertips Traumatic Amputations, Finger Injuries
Operative Treatment vs Treatment With Semi-occlusive Dressing for Single Finger Amputations
The goal of this interventional study is to find out whether conservative treatment with semi-occlusive film is superior to surgical treatment in single finger amputations in adult population.
- Conditions
- Fingertips Traumatic Amputations, Finger Injuries, Finger, Finger Injury
- Trial name
- FINACT (NCT07175675)
- Testing
- Operative treatment of surgeons choice, Semi-occlusive film
- Where
- Finland
- Volunteers
- 252 people
- Sponsor
- Tampere University Hospital
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Neck Pain, Musculoskeletal Diseases
Effectiveness of Scapula Mobilization on Mechanosensitivity of Upper Limb Neural Test 1 in Mechanical Neck Pain
Between 45% and 70% of the general population suffers neck pain at some point in their lives, making it one of the most frequent reasons for taking sick leave.
- Trial name
- ULNT1 (NCT04168476)
- Testing
- Interscapular muscle release or scapular mobilization technique as described by Travell and Simons., Calcaneus abduction and adduction mobilization technique
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aitor Vaquero Garrido
Hand Osteoarthritis
Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis?
Post-menopausal women aged 40-65 with symptomatic hand osteoarthritis are invited to take part in this feasibility study. The study's aim is to investigate whether it is acceptable to women with painful hand OA to take an…
- Trial name
- HOPE-e (NCT04036929)
- Testing
- Estrogen-bazedoxifene
- Where
- 3 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Oxford
Focal Dystonia
Motor Training to Treat Hand Dystonia
This study will evaluate the effect of motor training on focal hand dystonia in people with writer's cramp and will examine whether this training affects excitability of the motor cortex of the brain.
- Trial name
- NCT00021853
- Testing
- constraint-induced movement therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebrovascular Accident
Norwegian Constraint-Induced (CI) Therapy Multisite Trial
The purpose of this study is to determine whether modified CI therapy treatment is suitable and effective in the early rehabilitation after stroke, and to compare early CI intervention with a later CI intervention group.
- Trial name
- NORCIMT (NCT00906477)
- Testing
- Modified CI therapy
- Where
- 5 sites in Norway
- Volunteers
- 47 people
- Sponsor
- University Hospital of North Norway
Osteoarthritis in the Carpometacarpal (CMC) Joint
Occupational Therapy and Surgery in Carpometacarpal Osteoarthritis
The purpose of the study is to investigate if occupational therapy may delay or prevent the need for surgery in patients with carpometacarpal(CMC) osteoarthritis (OA) who are scheduled for surgery in the CMC-joint.
- Trial name
- NCT01794754
- Testing
- Care as usual, Occupational therapy
- Where
- 4 sites in Norway
- Volunteers
- 180 people
- Sponsor
- National Resource Center for Rehabilitation in Rheumatology
Complex Regional Pain Syndrome I (CRPS I)
CRPS-Hand: Contrast + Compression vs Whirlpool
This randomized controlled trial aims to evaluate and compare the effectiveness of combined contrast therapy with intermittent compression and whirlpool therapy in patients with post-traumatic CRPS-I of the hand and wrist, using…
- Trial name
- NCT07744269
- Testing
- Combined Contrast Therapy with Intermittent Compression, Whirlpool Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Increased Production of Tears
Will a Hands on Technique Applied to the Face Increase the Tear Production in Participants
The goal of this interventional study is to learn if a hands on technique will increase tear production in patients aged 45 and younger, without a history of eye issues.
- Trial name
- NCT07632183
- Testing
- sphenopalatine ganglion release
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Spastic Hemiplegic Cerebral Palsy
Effectiveness of Modified Constraint-Induced Movement Therapy Versus Mirror Therapy in Spastic Hemiplegic Cerebral Palsy Children
This randomized controlled trial was conducted to compare the effectiveness of Modified Constraint-Induced Movement Therapy (MCIMT) and Mirror Therapy in improving upper limb function among children with spastic hemiplegic…
- Trial name
- NCT07747974
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad