Clinical trials: Grit
Prodromal Alzheimer's Disease, Preclinical Alzheimer's Disease
TMS for Cognitive Decline in Aging and Preclinical AD
In this research study we want to learn more about the effects of non-invasive brain stimulation on motivation, memory, and brain-network function in cognitively unimpaired older adults and individuals with preclinical…
- Conditions
- Prodromal Alzheimer's Disease, Preclinical Alzheimer's Disease, Healthy Aging, Cognitive Decline
- Trial name
- NCT06956300
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Arrhythmogenic Cardiomyopathy, PKP2-ACM
Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
The primary objective of this Phase 1/2 long-term follow-up (LTFU) study is to assess the long-term safety and tolerability of LX2020 for the treatment of arrhythmogenic cardiomyopathy (ACM) due to a plakophilin-2 gene (PKP2)…
- Conditions
- Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
- Trial name
- GRIT-PKP2 (NCT07050160)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lexeo Therapeutics
Cognitive Impairment, Glioma
Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training
The TRUE-GRIT study will assess the feasibility of a study protocol investigating the efficacy of a combination therapy consisting of cognitive strategy training (CST) and repetitive transcranial magnetic stimulation (rTMS) to…
- Trial name
- TRUE-GRIT (NCT06043765)
- Testing
- real repetitive transcranial magnetic stimulation (rTMS), cognitive strategy training
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Linda Douw
Stress
Outcomes of a Small Process Group on Medical Students' Grit, Resilience, and Stress
The incidence of burnout and mental ill-health begins very early in medical school and continues to be high throughout training.
- Trial name
- NCT06003920
- Testing
- Process group
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Chronic Post-Traumatic Stress Disorder
G.R.I.T. - Goal-directed Resilience Intervention Training
This research program has addressed three reactive adaptations evident in pain, PTSD, and obesity. In this project, the focus will be on PTSD as a model of stimulus-based reactive responses to unpredictability or threat, and the…
- Trial name
- GRIT (NCT03890029)
- Testing
- Intervention Training, Control Condition
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Morehouse School of Medicine
Oral Frailty, Depression
Group Reading and Oral Exercise Program for Older Adults
Depression is common among older adults and is often associated with declines in physical and oral health. Non-pharmacological, community-based interventions are needed to support both mental and physical well-being.
- Conditions
- Oral Frailty, Depression, Sarcopenia, Physical Function Decline
- Trial name
- NCT07550335
- Testing
- Reading and Oral Exercise Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Suicide Prevention
Retreat-Based Program for Violence-Exposed Women Veterans
Given their elevated risk for suicide and barriers to engaging in VHA healthcare, violence-exposed women Veterans represent a specialized population for which expansions to current VHA programming are needed.
- Trial name
- GRIT (NCT07738445)
- Testing
- GRIT, GRI
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Resilience-based Intervention, Emotional Regulation, Grit and Life Satisfaction
The Impact of a Resilience-based Intervention on Emotional Regulation, Grit and Life Satisfaction: A Comparative Study Between Egyptian and Saudi Nursing Students
Nursing students may be perceived as having a stable college experience because they have a relatively clear career goal and a higher employment rate than students in other majors, but they consistently report that their heavy…
- Trial name
- NCT05828316
- Testing
- Resilience-based intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Glycemic and Insulinemic Response
Four-hour Glycemic Kinetic Response Following 13C-enriched Oatmeal Breakfast Compared to Hot Corn Grits
The objectives of this study are to assess the 4 hr postprandial kinetics of total and exogenous glucose in response to consumption of oatmeal containing a high percentage of the viscous agent β-glucan, in comparison to a…
- Trial name
- NCT03165773
- Testing
- Oatmeal, Corn grits
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Dental Implant
Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures…
- Trial name
- NCT06086873
- Testing
- Implant Type
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Stress, Psychological
Resilience, Grit, and Stress in Medical Students
The incidence of burnout and mental ill-health begins very early in medical school and continues to be high throughout training.
- Trial name
- NCT06046183
- Testing
- Process group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Anxiety
Grow With Grit: A School Nurse-Led SBIRT Pilot for Early Anxiety Detection
All enrolled students and their parents or guardians will complete baseline anxiety questionnaires. Students with a positive baseline screen will receive a brief school nurse-delivered coping skill, referral support when…
- Trial name
- GwG (NCT07766785)
- Testing
- Grow with Grit
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- McLaughlin Research Institute for Biomedical Sciences, Inc.
Artificial Intelligence (AI), Empathy
AI-Supported Empathy Mapping to Enhance Communication and Grit in Pediatric Nursing Students
The nurse-patient communication environment in pediatric care is characterized by high uncertainty and complexity. Due to children's limited language development and emotional regulation abilities, coupled with parents' high…
- Conditions
- Artificial Intelligence (AI), Empathy, Scaffolding, Pediatric Nursing
- Trial name
- NCT07370285
- Testing
- AI-Supported Empathy-Map Scaffolding Model
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital