Clinical trials: Furcation Defects
Chronic Periodontitis
Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis
Statins are one of the lipid lowering drugs that help in reducing cholesterol levels in the body by specifically inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase; which is a rate limiting enzyme for cholesterol…
- Trial name
- NCT02800902
- Testing
- Rosuvastatin, Atorvastatin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Chronic Periodontitis
1% Metformin Gel in the Treatment of Class II Furcation Defects
Metformin (MF), a biguanide group of anti-diabetic drug has been shown to enhance osteoblasts differentiation and inhibit osteoclast differentiation in vitro, thus may exhibit a favourable effect on alveolar bone.
- Trial name
- NCT02580331
- Testing
- SRP and 1% metformin
- Where
- India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects, Periodontal Diseases
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects
Teeth with furcation grade II defects will be treated with open flap debridement, with or without osteoplasty. The study is designed to examine the effect of osteoplasty in the treatment of teeth with furcation grade II defects…
- Trial name
- FURC-II-OST (NCT03917030)
- Testing
- Open flap debridement with osteoplasty, Open flap debridement without osteoplasty
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oslo
Furcation Defects
Evaluation of Injectable Beta-tricalcium Phosphate Clinically in Treatment of Grade II Furcation Involvement
This study will be conducted to evaluate clinically and radiographically the use of PD VitalOs cement® bone graft in the treatment of class II furcation defects comparing with Hydroxyapatite bone graft and biodegradable collagen…
- Trial name
- NCT04443972
- Testing
- PD VitalOs cement®, Hydroxyapatite bone graft, biodegardable collagen membrane
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Periodontitis
Bone Morphogenetic Protein-2 In Grade II Furcation Defects.
The present study evaluated clinically and radiographically the regenerative potential of rhBMP-2 in absorbable sponge and PRF in Grade II furcation.
- Trial name
- NCT04372420
- Testing
- RhBMP-2 absorbable sponge in grade II furcation, PLATELET RICH FIBRIN in grade II furcation
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Generalized Aggressive Periodontitis
EMD for Treatment of Proximal Class-II Furcation Involvements
The aim of the present study is to evaluate the clinical response of proximal furcations treated with enamel matrix derivative proteins (EMD).
- Trial name
- OFD (NCT03320135)
- Testing
- Enamel matrix derivative proteins, Open Flap debridement
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Furcation Defects
Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to evaluate the combined efficacy of PRF and 1% ALN in the treatment of mandibular degree II furcation defects when compared with PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02609061
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1% Alendronate (Drug) in gel form
- Where
- India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects
Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement
the effect Hyaluronic Acid in the Treatment of Furcation Involvement
- Trial name
- NCT04851548
- Testing
- hyaluronic acid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Furcation Defects
Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to explore the effectiveness of PRF combined with 1.2% ATV gel in treatment of mandibular degree II furcation defects in comparison to PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02612792
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1.2% Atorvastatin (Drug) in gel form
- Where
- India
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects, Periodontal Diseases
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
Teeth with furcation grade III defects will be treated with open flap debridement, with or without osteoplasty. The study is designed to examine the effect of osteoplasty in the treatment of teeth with furcation grade III defects…
- Trial name
- FURC-III-OST (NCT04017429)
- Testing
- Open flap debridement with osteoplasty, Open flap debridement without osteoplasty
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oslo
Furcation Defects
Comparison of Platelet Rich Fibrin as Graft & Membrane Vs Hyaluronic Acid & Amniotic Membrane in the Treatment of Interradicular Defects
This study is intended to compare the efficacy of platelet-rich fibrin as a graft and a membrane versus hyaluronic acid(Gengigel) and amniotic membrane in the treatment of mandibular grade II furcation defects.
- Trial name
- CPRFGMHATID (NCT03578744)
- Testing
- Conventional Flap surgery
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Furcation Defects
Piezosurgery in the Treatment of Class II Furcation Involvement
The purpose of this study is to evaluate the effectiveness of piezosurgery in the treatment of class II furcation involvement using biomaterials and new surgical techniques
- Trial name
- NCT02132806
- Testing
- Piezosurgery with biomaterial mp3 + bracket, Piezosurgery with biomaterial mp3, Piezosurgery
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Matteo Visintin
Chronic Periodontitis
Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis
Alendronate (ALN), commonly use bisphosphonates is proposed to have osteostimulative properties in vivo and in vitro, as shown by an increase in the matrix formation, and acts as a potent inhibitor of bone resorption.
- Trial name
- NCT03204097
- Testing
- Alendronate, Aloe Vera
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore