Clinical trials: Furcation Defects
Injectable Platelet-Rich Fibrin, Minimally Invasive
Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation Defects
This study aims to compare the clinical and radiographic effectiveness of injectable platelet-rich fibrin (i-PRF) combined with minimally invasive non-surgical therapy (MINST) versus MINST alone in the management of class II…
- Conditions
- Injectable Platelet-Rich Fibrin, Minimally Invasive, Non-Surgical Technique, Grade II Furcation Defects
- Trial name
- NCT07787949
- Testing
- Minimally invasive non-surgical technique (MINST), Minimally invasive non-surgical technique (MINST) + injectable platelet-rich fibrin (i-PRF) injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Periodontal Diseases, Furcation Defects
Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study
The goal of this clinical trial is to test in 10 patients with advanced furcation involvement on molars. The main question[s] it aims to answer are: Is it possible to carry out root resection without endodontic treatment on…
- Trial name
- NCT05721313
- Testing
- root resection
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Periodontitis, Adult, Furcation Defects
A Chitosan Brush and Enamel Matrix Derivative for Non-surgical Treatment of Furcations
Patients diagnosed with stage III or IV periodontitis who exhibit mandibular first or second molars with Class II, Subclass A, or B buccal and/or lingual mandibular furcation defects (horizontal probing depth of ≥ 3 mm ) will be…
- Conditions
- Periodontitis, Adult, Furcation Defects, Furcation of Root of Tooth, Periodontitis Complex
- Trial name
- NCT06684769
- Testing
- Emdogain® FL, Labrida BioClean®
- Where
- Latvia
- Volunteers
- 40 people
- Sponsor
- Riga Stradins University
Periodontitis, Periodontitis (Stage 3)
Morphological Characteristics of Mandibular Molar Furcation Involvement and Efficacy of Regenerative Surgical Treatment
This study consists of two components evaluating furcation involvement in mandibular molars among Stage III or Stage IV periodontitis patients.
- Conditions
- Periodontitis, Periodontitis (Stage 3), Furcation Defects
- Trial name
- NCT07770256
- Testing
- Acellular Dermal Matrix + EMD + Xenograft, Autogenous Connective Tissue Graft + EMD + Xenograft
- Where
- Vietnam
- Volunteers
- 98 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Furcation Defects
Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case Series
Furcation involvement represents a challenge for treatment to many periodontists due to many factors including access, morphology, and variations of anatomical features of the furcation area.
- Trial name
- NCT06060340
- Testing
- class II furcation defects management using propolis
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Furcation Defects, Periodontal Disease
Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.
This clinical study compared a conventional surgical technique (CST) and a minimally invasive surgical technique (MIST) in the regenerative treatment of mandibular furcation defects.
- Trial name
- NCT02102360
- Testing
- Anorganic Bovine Bone, Enamel Matrix Derivative
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontitis, Periodontal Diseases
MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars
Aim of this prospective study is to compare magnetic resonance imaging (MRI) and cone beam computed tomography (CBCT) to diagnose furcation involvement (FI) in molars in patients with periodontitis.
- Conditions
- Periodontitis, Periodontal Diseases, Furcation Defects
- Trial name
- NCT06116487
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Class II Furcation Defect
Treatment of Class II Mandibular Furcation Defects
The aim of this study is to investigate the clinical efficiency and radiographic outcomes following minimally invasive surgical technique with xenograft and i-PRF versus i-PRF in the management of class II furcation defects in…
- Trial name
- NCT07876973
- Testing
- Injectable-PRF (I-PRF), sticky bone (I-PRF+Xenograft)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Peridontal Disease, Furcation Defects
PRF Versus Emdogain for Class II Furcation Defects of Mandibular Molars
This study evaluated the regenerative potential of platelet-rich fibrin (PRF) compared with enamel matrix derivative (Emdogain®) in the surgical treatment of Class II (F2) furcation defects of mandibular molars.
- Trial name
- NCT07841301
- Testing
- Platelet rich fibrin, Emdogain
- Where
- Bulgaria
- Volunteers
- 21 people
- Sponsor
- Medical University of Sofia
Furcation Defects
Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects
Rosuvastatin (RSV) is a new synthetic, second-generation, sulfur-containing, hydrophilic statin, that stimulate bone formation in critical-size cortical bone defects adjacent to titanium implants, when administered locally in…
- Trial name
- NCT02369250
- Testing
- Rosuvastatin, platelet rich fibrin
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects
Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation Involvement
Furcation involvement (FI) refers to a condition in which the progression of the periodontal disease process invades the bifurcation and trifurcation of multirooted teeth.
- Trial name
- NCT07642895
- Testing
- Behavioural text messages twice weekly, Standardized oral hygiene instructions
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Furcation Defects
Effect of Two Irrigation Protocols Applied Prior to Furcation Repair
Perforations are mishaps that might occur during the course of endodontic treatment mainly due to iatrogenic factors. However, they might also occur due to extensive decay of dentinal structure.
- Trial name
- NCT06757660
- Testing
- Furcation Repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Periodontitis, Furcation Defects
Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
The aim of this randomized clinical trial is to evaluate the potential benefit of the use of a bone substitute material in the treatment of furcation degree II-involved molars.
- Trial name
- NCT06270303
- Testing
- Access flap & surgical debridement, Application of bone substitute material (BioOss Collagen)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Class II Furcation Defect
Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation Defects
This randomized controlled clinical trial aims to compare two regenerative surgical approaches for the treatment of mandibular molar Class II furcation defects in patients with periodontitis.
- Trial name
- NCT07776756
- Testing
- Periodontal Regenerative Surgery With Xenograft and Enamel Matrix Derivative, Periodontal Regenerative Surgery With Xenograft and Collagen Membrane
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Furcation Defects
Bovine Pericardium Membrane Versus Native Collagen Membrane in Conjunction With Sticky Bone Graft in Treatment of Class II Furcation Defects in Lower Molars.
Materials and methods: Twenty five patients (n=25) were selected from the outpatient clinic of the department of oral medicine and periodontology at Mansoura university's faculty of dentistry, 5 patients (n=5) were excluded as…
- Trial name
- NCT06681532
- Testing
- Native collagen membrane and bovine bone graft in treatment of class II furcation defects in lower molars, Bovine pericardium membrane and bovine bone graft in treatment of class II furcation defects in lower molars
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ibrahim Ahmed Zein Elabdin Ahmed
Furcation Defects, Periodontitis
Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis
Purpose: The proposed study will evaluate and compare the clinical response of using bioresorbable collagen membrane alone or defect debridement with erbium Laser irradiation in conjunction with bioresorbable collagen membrane in…
- Conditions
- Furcation Defects, Periodontitis, Alveolar Bone Loss Beyond Furcation
- Trial name
- NCT01522131
- Testing
- bioresorbable membrane alonewill be used for regeneration of the periodontium(control)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Furcation Defects
Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement
the effect Hyaluronic Acid in the Treatment of Furcation Involvement
- Trial name
- NCT04851548
- Testing
- hyaluronic acid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Furcation Defects, Periodontal Diseases
Mandibular Furcation III Regeneration (FURC-III-REGEN)
Teeth with furcation grade III defects will be treated with open flap debridement and regenerative therapy with biphasic calcium phosphate combined with either enamel matrix proteins or a collagen membrane.
- Trial name
- FURC-III-REGEN (NCT04059458)
- Testing
- Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane), Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain)
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Periodontal Diseases
Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration
The purpose of this pilot project is to evaluate the efficacy of application of Amnion-Chorion allograft membrane on the root surface of periodontally diseased teeth in conjunction with bone substitute covered by Amnion-Chorion…
- Trial name
- NCT03095976
- Testing
- Amnion-Chorion allograft membrane on the root surface of periodontally diseased site.
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Indiana University
Furcation Defects, Periodontitis
Non-surgical vs. Surgical Therapy for Periodontal Furcations
Periodontitis is an inflammatory disease of the tooth-supporting apparatus, which leads to attachment and bone loss and eventually to tooth loss if treatment is not provided.
- Conditions
- Furcation Defects, Periodontitis, Surgical Procedure, Unspecified
- Trial name
- NCT05237401
- Testing
- Non-Surgical Periodontal treatment (NSPT), Surgical Periodontal treatment/ Open Flap Debridement (OFD)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- King's College London