Clinical trials: Functional Magnetic Resonance Imaging
Neurofeedback, Cognitive Training
Neurofeedback Removal of Emotional Information From Mind
This project will examine whether individuals can be trained, using real-time feedback about brain function during neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to…
- Conditions
- Neurofeedback, Cognitive Training, Memory, Short-Term, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- remtrain (NCT06460207)
- Testing
- fMRI neurofeedback
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Obsessive-Compulsive Disorder, OCD
Neurofeedback for Treatment-resistant Obsessive-compulsive Disorder (OCD)
The aim of this study is to teach participants with a OCD diagnosis and treatment-resistance how to decrease the response from a brain region involved in the disease by using a technique called neurofeedback.
- Trial name
- NCT03956771
- Testing
- Real neurofeedback
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Pedro Morgado
Healthy
NeuroCognitive Bases of Tool Use
Tool use is considered to be the hallmark of complex cognitive adaptations that humans have achieved trough evolution, that provides an adaptive advantage to the human species.
- Trial name
- TECHNITION (NCT04566744)
- Testing
- fRMI
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Breast Cancer
Breast Reconstruction and Body Map : Assessment by Functional MRI (REMASCO)
Breast reconstruction is an integral part of the management of patients with breast cancer and treated by total mastectomy. The aim of breast reconstruction is to get a satisfying aesthetic and functional result (sensitivity) and…
- Trial name
- REMASCO (NCT02553967)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Oscar Lambret
Healthy Volunteers
Healthy Lung Study- Development of 3T MRI Hardware and Software for 3He Gas Imaging of the Lung: Healthy Volunteer Development Study
Healthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
- Trial name
- NCT03169673
- Testing
- Hyperpolarized Helium 3 Magnetic Resonance Imaging
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Smoking Cessation
Neuroimaging Studies of Smoking and Treatment
The purpose of this research study is to examine changes in brain regions associated with cognitive control and reward processing during behavioral smoking cessation treatment.
- Trial name
- NCT03085602
- Testing
- Cognitive behavioral therapy, Health education
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Generalized Anxiety Disorder
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) as an adjunctive treatment for generalized anxiety disorder (GAD).
- Trial name
- NCT07392645
- Testing
- Electroacupuncture (EA), Medication
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Lishu Gao
Post Traumatic Stress Disorder
Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)
This study will examine the effects of psychotherapy as treatment for PTSD, and specifically how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) and an active mind-body comparison…
- Trial name
- NCT03874793
- Testing
- Mindfulness-Based Cognitive Therapy, Muscle Relaxation Therapy
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Ohio State University
Irritable Bowel Syndrome
Effect of Menstrual Cycle on Central Nervous System (CNS) Processing of Gut Stimuli in Irritable Bowel Syndrome (IBS) and Control
The hypothesis of the study is that women perceive intestinal stimulation (rectal balloon distention) differently in different phases of the menstrual cycle, i.e there is an effect of hormones on the sensory pathway, and that…
- Trial name
- NCT00219531
- Testing
- perception of rectal balloon distention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Posttraumatic Stress Disorder
Imaging Outcomes of Cognitive Behavioral Therapy (CBT) for Battered Women With Posttraumatic Stress Disorder
Identifying neural mechanisms of posttraumatic stress disorder (PTSD) treatment could help elucidate reasons for variable treatment response and identify novel treatment targets.
- Trial name
- NCT01517672
- Testing
- Cognitive Trauma Therapy for Battered Women (CTT-BW)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Stroke, Blindness
Functional Neuroimaging of Cortical Plasticity in the Human Visual System
The study's objective is to measure changes in human visual cortex organization that may arise as a result of injury to the visual pathways.
- Conditions
- Stroke, Blindness, Vision
- Trial name
- NCT01062672
- Where
- 2 sites in United States, Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Repetitive Transcranial Magnetic Stimulation, Stroke
Comparative Effectiveness of Ipsilesional High-frequency rTMS, Contralesional Continuous Burst Theta rTMS, and Sham rTMS, Each Combined With Physiotherapy, in Subacute Ischemic Stroke Upper Limb Recovery : Clinical, Neurophysiological and Radiological
To compare the efficacy of lesional high-frequency rTMS, contralesional cTBS, and sham stimulation in improving motor and cognitive recovery in post-stroke patients undergoing physiotherapy.
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Stroke, Functional MRI
- Trial name
- NCT06799312
- Testing
- Ipsilesional high frequency rTMS combined with physiotherapy, Contralesional Continuous Burst Theta rTMS (cTBS) + Physiotherapy
- Volunteers
- 90 people
- Sponsor
- Assiut University
Spinal Cord Injuries
Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
Early detection of response to therapeutic intervention is vital, as it will enable early termination of intervention in non-responding patients, prevent unnecessary financial burden, and allow for early changes to the…
- Trial name
- NCT03854214
- Testing
- Functional Electric Stimulation cycling, Passive cycling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Chronic Heart Failure (CHF)
Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
This study was a multi-center, randomized, double-blind, parallel group, active comparator trial designed to evaluate the overall effect of LCZ696 compared to valsartan on cognitive function as assessed by the CogState…
- Trial name
- PERSPECTIVE (NCT02884206)
- Testing
- LCZ696, Valsartan
- Where
- 135 sites in United States, Argentina and 18 more
- Volunteers
- 592 people
- Sponsor
- Novartis Pharmaceuticals
Parkinson Disease
Individualized Precise Localization of rTMS on Primary Motor Area
Parkinson's disease (PD) patients have some problem with self-initiated movement task. Compared with health controls, task meta-analysis found that PD patients showed abnormal activation in pre-supplementary motor area (pre-SMA)…
- Trial name
- NCT03497884
- Testing
- rTMS
- Where
- 2 sites in China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Muscle Oxygenation
Evaluation of Muscle Oxygen With MRI
Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.
- Trial name
- NCT07638384
- Testing
- Compression and Contraction
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Hemiparesis
Safety and Effectiveness of Cortical Stimulation in the Treatment of Stroke Patients With Upper Extremity Hemiparesis
The purpose of this study is to assess the safety and effectiveness of cortical stimulation delivered concurrent with rehabilitation activities to enhance motor recovery in patients suffering from hemiparesis affecting the upper…
- Trial name
- EVEREST (NCT00170716)
- Testing
- Cortical Stimulation and rehabilitation, Rehabilitation
- Where
- 21 sites in United States
- Volunteers
- 174 people
- Sponsor
- Northstar Neuroscience
Ideomotor Apraxia
Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements
Ideomotor apraxia, a disorder that affects patients with stroke and a variety of other brain lesions, features disturbed timing, sequence, and spatial organization of skilled movements.
- Trial name
- NCT00063115
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Participant Study
MRI-tDCS Criticism Study
This experimental study investigated how MRI-compatible transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) modulates neural and cognitive responses to social criticism in healthy…
- Trial name
- NCT07406464
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
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