Clinical trials: Frail Elderly Syndrome
Frail Elderly Syndrome
A Health Promotion Program to Prevent Frailty and Improve Frailty Status Among Pre-frail Elderly: Frailty Intervention Through Nutrition Education and Exercises.
Prevention of frailty is a major concern in geriatrics due to its high prevalence and various adverse health outcomes among elderly population.
- Trial name
- FINE (NCT04327544)
- Testing
- Frailty Intervention
- Where
- Malaysia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Frail Elderly Syndrome
Enhanced Primary Care for Elderly
The present health care situation for the elderly in many countries is insufficient and not designed according to the health care needs of the aged population.
- Trial name
- NCT03180606
- Testing
- Multi-disciplinary and personalized primary care
- Where
- 2 sites in Sweden
- Volunteers
- 1,304 people
- Sponsor
- Region Östergötland
Frailty Syndrome, Respiratory Muscle Weakness
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on diaphragmatic and respiratory muscle function in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Respiratory Muscle Weakness, Age-Related Frailty, Geriatric Health
- Trial name
- IMT-1 (NCT07258615)
- Testing
- Inspiratory Muscle Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Frailty Syndrome, Prehabilitation
Multimodal Prehabilitation of Frail Patients Undergoing Elective Knee or Hip Replacement
Background: Frailty is a geriatric syndrome of reduced physiologic reserve that increases surgical risk and is common among older adults undergoing hip or knee replacement.
- Conditions
- Frailty Syndrome, Prehabilitation, Arthroplasties, Knee Replacement, Arthroplasties, Hip Replacement
- Trial name
- NCT07465159
- Testing
- Multimodal Prehabilitation
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- University of Iceland
Frail Elderly Syndrome, Chronic Disease
Implementing Advance Care Planning Conversation Tools in Family Practice
This study evaluates the use of advance care planning conversation tools with patients attending their family doctor's office. Patients complete tools about their values and wishes, and a health care provider uses a structured…
- Trial name
- NCT03508557
- Testing
- Advance care planning tools
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- McMaster University
Cognitive Impairment, Frail Elderly Syndrome
Cognition and the Immunology of Postoperative Outcomes
This research will test the hypothesis that immune system disequilibrium / dysfunction explains why preoperative cognitive impairment is a strong predictor of postoperative morbidity in older surgical patients.
- Conditions
- Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery
- Trial name
- NCT04792983
- Testing
- No intervention
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Frailty, Frailty Syndrome
Maintaining and imPrOving the intrinSIc capaciTy Involving Primary Care and caregiVErs
The POSITIVE platform offers the possibility of unsupervised monitoring of pre-frailty and frailty status in a community setting, to detect the onset of frailty and to assess its evolution.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- POSITIVE (NCT04592146)
- Testing
- Frailty multicomponent intervention supported by POSITIVE, Frailty multicomponent intervention
- Where
- 3 sites in Poland, Spain and 1 more
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Getafe
Frailty, Frail Elderly Syndrome
The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging
This clinical study, designed as a double-blind, randomized, placebo-controlled trial, aims to investigate the potential of nicotinamide riboside (NR) to decelerate functional decline in the elderly frail population.
- Conditions
- Frailty, Frail Elderly Syndrome, Frailty Syndrome, Aging
- Trial name
- NADage (NCT06208527)
- Testing
- Nicotinamide Riboside (NR)
- Where
- 2 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Frail Elderly Syndrome
Low Intensity Training Combined With KAATSU on Muscle Vasodilatation and Arterial Stiffness in the Elderly Population
The purpose of the present study is to evaluate the acute and chronic effect of low intensity strength training with or without moderate blood flow restriction on muscle vasodilation and arterial stiffness in elders with low gait…
- Trial name
- NCT03272737
- Testing
- 1RM Test, Speed gait test, Venous occlusion plethysmography protocol
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Frail Elderly Syndrome
Frailty and Complexity Among Home Service Recipients
The purpose of the study is to develop frailty and complexity computation algorithms based on the French version of the interRAI-HC and, in doing so, to provide homecare nurses with valid and reliable screening tools for their…
- Trial name
- fraXity (NCT03883425)
- Testing
- interRAI-HC assessments
- Where
- Switzerland
- Volunteers
- 231 people
- Sponsor
- School of Health Sciences Geneva
Cognitive Deterioration
Safe & Easy Environment at Home for Patients Presenting a Frail Syndrome
All over the world the increasing prevalence of chronic disorders and its impact on functional decline is challenging the sustainability of health care systems.
- Trial name
- SafEE (NCT02288221)
- Testing
- Patient's answer with non pharmacological therapeutic, Patient's answer without non pharmacological therapeutic
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Heart Failure, Frail Elderly Syndrome
Discharge Planning in Emergency Department for Frail Older With AHF
Objectives: To demonstrate the efficacy of care transition holistic intervention (Multilevel Guided Discharge Planning, MGDP) in reducing 30-day adverse outcomes among frail older patients with acute heart failure (AHF)…
- Trial name
- NCT03696875
- Testing
- Multilevel Guided Discharge Planning, Standard of care
- Where
- Spain
- Volunteers
- 1,260 people
- Sponsor
- F. Javier Martin Sanchez
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Frail Elderly Syndrome
HOPE (Healthy Older People Everyday) To Age in Place
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment, falls in older adults carry an increased risk for poor health outcomes and if identified early, can be prevented…
- Trial name
- NCT03797352
- Testing
- Multicomponent exercise
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Frail Elderly Syndrome
Frailty Assessment and Treatment Strategies in the Elderly at Risk of Functional Decline in the Community
This study aims to design a patient -centered program to prevent or delay frailty , functional decline and adverse events, and evaluates the effectiveness of the program with a randomized clinical trial.
- Trial name
- NCT03591055
- Testing
- CGA, medication review, exercise and cognitive stimulation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frail Elderly Syndrome, Coronary Heart Disease
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
The impact of frailty on immediate and long term outcomes of invasive treatment of coronary artery disease is not fully characterized.
- Conditions
- Frail Elderly Syndrome, Coronary Heart Disease, Acute Coronary Syndrome, Coronary Artery Bypass Grafting
- Trial name
- FRAPICA (NCT03209414)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Silesia
Diabetes Type 2, Frail Elderly Syndrome
Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of Exercise
This study aims to investigate the role of skeletal muscle mitochondrial dysfunction in the development of frailty in older adults and to evaluate whether a short-term, supervised resistance training intervention can improve…
- Conditions
- Diabetes Type 2, Frail Elderly Syndrome, Mitochondrial Function, Bioenergetics, Functionality
- Trial name
- MITOSTRENGTH (NCT07828847)
- Testing
- Short-duration resistance training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Frail Elderly Syndrome, Triage
The Prediction Model of Elderly Patients in Taiwan Triage and Acuity Scale
In the year of 2010, the Taiwan Ministry of Health and Welfare had implemented the 5-level Taiwan Triage and Acuity Scale(TTAS) in Taiwan emergency department. TTAS is a triage system that was modified from CTAS.
- Trial name
- NCT04862936
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Chang Gung Memorial Hospital
Frail Elderly Syndrome
A Machine Learning Algorithm to Predict Health Clinical Situations in Primary Healthcare for Frail Older Adults.
Introduction: We developed a machine learning algorithm to predict the risk of emergency hospitalization within the new 7 to 14 days with a good predictive performance (AUC=0.85).
- Trial name
- NCT06013709
- Testing
- PRESAE CARE
- Volunteers
- 1,478 people
- Sponsor
- Presage