Clinical trials: Frail Elderly
Cognitive Dysfunction, Mobility Limitation
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain…
- Conditions
- Cognitive Dysfunction, Mobility Limitation, Frail Elderly
- Trial name
- NCT05830942
- Testing
- Walking Exercise, Prefrontal Active tDCS
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults
This is a pilot study to test the efficacy of the anti-inflammatory drug (Fisetin) in reducing inflammatory factors in blood in elderly adults and to test the efficacy of the drug (Fisetin) in reducing frailty and markers of…
- Trial name
- AFFIRM-LITE (NCT03675724)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Frail Elderly Patients, Geriatric Syndromes
Improving Care for Frail Older Adults Using a Digital Needs Assessment Tool
The goal of this trial is to evaluate whether a digital needs-assessment tool can improve care planning and outcomes for frail older adults (aged 60 years and above) hospitalized in Singapore.
- Conditions
- Frail Elderly Patients, Geriatric Syndromes, Frail Older Adults
- Trial name
- Frailty (NCT07580690)
- Testing
- Core: SST-informed care planning, Additional telephone calls
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Duke-NUS Graduate Medical School
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women
This is a pilot study to evaluate whether targeting inflammation will help reduce markers of insulin resistance inflammation, bone resorption and physical dysfunction in elderly women with gait disturbance.
- Trial name
- AFFIRM (NCT03430037)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Heart Failure, Prefrail Elderly
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure.
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- Trial name
- TeleRiab4Fra (NCT07561021)
- Testing
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Volunteers
- 70 people
- Sponsor
- University of Salerno
Frail Elderly Patients, Hypogonadal Males
Effect of Testosterone on Elderly Frail Men With Testosterone Deficiency
The purpose of this study is to increase the functional level of the elderly to thereby reduce fall risk, improve motor skills, and increase psychological well-being, as well as to assess whether the restoration of a normal…
- Conditions
- Frail Elderly Patients, Hypogonadal Males, Testosterone Replacement Therapy, Falls (Accidents) in Old Age
- Trial name
- NCT07512323
- Testing
- Nebido (Testosterone Undecanoate)
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Rune Skovgaard Rasmussen
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Frail Elderly
Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults
The current study seeks to examine the prevalence of amyloid pathology, among patients referred to the Toulouse Geriatric Frailty Clinic presenting objective memory impairment.
- Trial name
- COGFRAIL (NCT03129269)
- Testing
- MRI and PET scan
- Where
- France
- Volunteers
- 344 people
- Sponsor
- University Hospital, Toulouse
Frail Elderly
Comparison of the Effects of Different Exercise Protocols in Frail Elderly Individuals
The aim of this research is to investigate and compare the effects of two different exercise programs developed for frail geriatric individuals on fall risk, fear of falling, and physical performance.
- Trial name
- NCT07564076
- Testing
- Vivifrail Exercise Program, Otago Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Frail Elderly Syndrome
Assessing a New Tool to Assess Frailty in Frail Hospitalized Elderly
The major purpose of this study is to establish the use of daily step counts as inexpensive, easy to measure marker for frailty and sarcopenia in an inpatient population of older adults.
- Trial name
- NCT04366388
- Testing
- ActivPAL3 VT (PAL Technologies Ltd).
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Aging, Frail Elderly
EFFECT OF ANIMATION-BASED DIGITAL EDUCATION ON RISK KNOWLEDGE AND FRAILTY IN OLDER ADULTS
With the global aging trend, the management of geriatric risks faced by older adults and the effectiveness of health education for this population are gaining increasing importance.
- Conditions
- Aging, Frail Elderly, Geriatric Syndromes
- Trial name
- NCT07547358
- Testing
- Branching Scenario Animation Education
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi
Heart Failure With Preserved Ejection Fraction, Sarcopenia
Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure.
The main objective of the study is to assess the effectiveness of a cardiac rehabilitation program on functionality, measured by kinematic analysis, cardiorespiratory capacity, and ventricular ejection fraction in elderly…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Sarcopenia, Frail Elderly Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- FUNNEL+ (NCT05393362)
- Testing
- Cardiac Rehabilitation Program (CR), Control Group (CG)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Malaga
Elderly Inpatients, Frail
Prevalence and Influencing Factors of Frailty in Elderly Patients With Heart Failure
The goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure.
- Conditions
- Elderly Inpatients, Frail, Heart Failure Hospitalization, CGA
- Trial name
- NCT07510035
- Where
- China
- Volunteers
- 298 people
- Sponsor
- Zhejiang Hospital
Frail Elderly People Hospitalized
Predictors of Physical Improvement in Frail Hospitalized Elders After Nutrition and Exercise
This study aims to evaluate whether a 12-week program combining oral nutritional supplements (ONS) with resistance exercises can improve nutritional status, muscle strength, and physical mobility in hospitalized older adults with…
- Trial name
- NCT07429630
- Testing
- Combined ONS and Resistance Training Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Hospital
Dementia, Hip Fracture
Communication for Early Mobilisation of People Living With Dementia Following Surgery for Hip Fracture
This goal of this study is to identify ways that healthcare professionals communicate that are effective in helping a person living with dementia to stand or walk after surgery for a broken hip (hip fracture).
- Conditions
- Dementia, Hip Fracture, Early Mobilisation, Communication Research
- Trial name
- VOICE-HF (NCT07418268)
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
Frail Elderly
Community-Based Program Integrating Nurse-Led Mind-Body Exercise and Nutrition for Frailty
This study aims to develop and evaluate a community-based rehabilitation program integrating nurse-led mind-body exercises and nutritional supplementation for frail older adults in Indonesia.
- Trial name
- N-CARE Frailty (NCT07418762)
- Testing
- Nurse-Led Mind-Body Exercise (MBE)
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Universitas Airlangga
Rehabilitation Frail Elderly Subjects
Study of the Impact of Implicit Motor Training in a Rehabilitation Programme in Frail Elderly Subjects
Even though cognitive-motor performances are impaired in frail elderly subjects compared with healthy elderly subjects, exercising cognitive-motor processes in an implicit manner can improve the carrying out of real actions in…
- Trial name
- MAAMI (NCT02855853)
- Testing
- serious game et virtual reality, Nintendo Wii
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Frailty, Frail Elderly
Synergizing Home Health Rehabilitation Therapy
The objective of this project is to pilot test an ADL (activities of daily living)-enhanced program as an adjuvant therapy to usual home health rehabilitation to improve patient outcomes.
- Conditions
- Frailty, Frail Elderly, Occupational Therapy, Activities of Daily Living
- Trial name
- NCT05411393
- Testing
- ADL-enhanced program, Usual home health rehabilitation therapy
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Frail Elderly Syndrome, Mild Cognitive Impairment
Spanish Linguistic Validation, Validity and Reliability Test of Frail´BESTest in Elderly Institutionalized Frail People
The aging of the global population presents significant social and health challenges. In Aragón, 15% of the population is between 65 and 79 years old, and the over-aging index is 16.6%, higher than the national average.
- Trial name
- NCT06438718
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón