Clinical trials: Fluid Management
Intestinal Obstruction Fluid Management With Hypertonic Saline
Comparison Between Two Concentration of Hypertonic Saline in Intestinal Obstruction Surgery
Background and Rationale : Perioperative fluid management is a challenging issue in surgical care especially in a procedure specific model.
- Trial name
- NCT03741257
- Testing
- Hypertonic saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Perioperative Fluid Management
Comparison of Perioperative Standard Fluid Management and Goal-Directed Fluid Management
To compare the goal-directed fluid therapy based on the data obtained from the hemodynamic monitoring system, which provides continuous CO, SV and SVV measurements through arterial pressure wave with standard fluid therapy in…
- Trial name
- NCT04728178
- Testing
- Crystalloid solution, Colloid solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Brain Tumor, Craniotomy
Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy
Pulse pressure variation (PPV) to standard fluid management (4ml/Kg/hr) in patients undergoing supratentorial mass excision. The investigators hypothesize that in these procedures, goal-directed fluid therapy (GDT) might improve…
- Trial name
- NCT03033706
- Testing
- Pulse pressure variation guided fluid therapy, Traditional fluid therapy, Brain tumor excision
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Cytomegalovirus Retinitis, HIV Infections
A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)
To assess the relative efficacy of oral versus intravenous hydration during foscarnet sodium (Foscavir) induction therapy, as determined by changes in creatinine clearance.
- Trial name
- NCT00002125
- Testing
- Foscarnet sodium
- Where
- 11 sites in United States
- Volunteers
- 112 people
- Sponsor
- Astra USA
Endometriosis, Infertility
GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
The investigators attempted to establish a rationale for the Gonadotropin Releasing Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild endometriosis (until stage II, according to AFS) who underwent…
- Trial name
- NCT01269125
- Testing
- Leuprolide, IVF
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Ioannina
Renal Transplant, DGF
Does Early Postoperative Fluid Management Affect Functional Delayed Graft Function After Living Donor Kidney Transplantation?
Fluid management in renal transplantation is of critical importance for optimizing graft function and minimizing complications such as delayed graft function (DGF) and acute kidney injury (AKI).
- Trial name
- NCT07392996
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ankara University
Bowel Resection
The Effect of Fluid Management by SVV of FloTrac/ Vigileo™ Monitoring on Postoperative Recovery in Bowel Resection
During an enterectomy, especially in an open surgery, large amounts of fluid are administered in consideration of the patient's fasted state, maintaining blood pressure during surgery and potential third space loss.
- Trial name
- NCT02288767
- Testing
- Conventional arterial blood pressure monitoring, Stroke volume variation monitoring with arterial blood pressure monitoring
- Where
- South Korea
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Goal Directed Fluid Therapy
Goal Directed Fluid Therapy
Intraoperative fluid demand will be monitored by Esophageal Doppler in lean and obese patients.
- Trial name
- FLO1 (NCT00860704)
- Testing
- fluidotherapy with ringer-lactate
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
Hypotension on Induction
Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal…
- Trial name
- NCT05891951
- Testing
- Fluid therapy under the guide of Carotid ultrasound
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Min Su
Acute Renal Failure on Dialysis (Disorder)
Prescription-based Fluid Management Versus Usual Care in Critically Ill Patients on KRT Trial in UK
The PROBE Fluid UK randomised controlled trial compares a protocol-based fluid removal strategy with usual care in critically ill patients with acute kidney injury receiving kidney replacement therapy.
- Trial name
- PROBE Fluid UK (NCT06471777)
- Testing
- Fluid removal
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Perioperative Care, Hemodynamics
ImPortance of Arterial Measurement Sites (IPAMS) on Intraoperative Hemodynamic Management
The goal of this clinical trial is to demonstrate the importance of arterial pressure measurement sites during major abdominal surgeries.
- Conditions
- Perioperative Care, Hemodynamics, Monitoring Blood Pressure, Arterial Lines
- Trial name
- IPAMS (NCT06982001)
- Testing
- Brachial line guided hemodynamic management, Radial line guided hemodynamic management, Radial line catheterization
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Respiratory Distress Syndrome, Adult
Non-invasive Fluid Management
For patients with a condition called acute respiratory distress syndrome (ARDS), managing their fluid levels to achieve a negative balance helps to improve their outcomes.
- Trial name
- DECAF (NCT02892799)
- Testing
- NICOM-Guided Diuresis, Standard of Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Intermountain Health Care, Inc.
Surgery-Complications
Restrictive- vs Individualized Goal Directed Fluid Therapy in Liver Surgery
"Low central venous pressure (low-CVP) or a restrictive fluid administration strategy is usually used worldwide during major liver resection surgery.
- Trial name
- REVOLUTION (NCT05704387)
- Testing
- individualized GDFT, Restrictive fluid therapy strategy
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intraoperative Hypotension
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia.
- Trial name
- NCT07301307
- Testing
- Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Hypovolemia, Fluid Overload
Prediction of the Effect of Fluid Administration Using Arterial Pressure and Ventilator Data During Abdominal Surgery
It is well known, that patients with circulatory impairment sometimes, but not always, benefit from intravenous fluids. Predicting if a fluid administration will improve circulation is therefore of substantial clinical interest.
- Trial name
- NCT04298931
- Testing
- Series of ventilator settings
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Post Operative Fluid Management
Fluid Management Surgical Patients in Intensive Care Unit.
The aim of this study is to evaluate the efficacy of lactate clearance (LCR) versus central venous oxygen saturation (ScVO2) to guide fluid management for post-operative patients in the intensive care unit (ICU).
- Trial name
- NCT03455296
- Testing
- fluid therapy; crystalloid
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Hemodialysis Patient
A Theory-based Fluid Self-management Program
This study aims to evaluate the efficacy of an intervention guided by the IFSMT, in which structured education and digitally delivered reinforcement strategies are designed to enhance self-management processes, including…
- Trial name
- NCT07677605
- Testing
- A Theory-based fluid self-management program
- Where
- Indonesia
- Volunteers
- 160 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Fluid Management
Hemodynamic Optimization Based on a Dynamic Elastance Protocol
In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery.
- Trial name
- NCT05187273
- Testing
- Elastance Group
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Liver Transplantation
The Effect of Norepinephrine on Cardiac Output in Patients Undergoing Liver Transplant .
Early administration of NE in liver transplant recipient might enhance cardiac output through an increase in cardiac preload .
- Trial name
- NCT04376281
- Testing
- Noradrenaline
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
End Stage Renal Disease
Goal Directed Fluid Administration for Kidney Transplantation
The goal of the proposed study is to evaluate the efficacy of a goal-directed fluid administration algorithm on early graft function in patients undergoing kidney transplantation.
- Trial name
- NCT02192086
- Testing
- goal directed fluid therapy, Control Group
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina