Clinical trials: Fistula
Chronic Subdural Hematoma
Spinal CSF Leaks in Chronic Subdural Hematoma
Background: Chronic subdural hematoma (cSDH) is a type of intracranial bleeding, predominantly affecting the elderly and males, with an estimated incidence of 8/100.000.
- Trial name
- SPICE (NCT06323434)
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University of Freiburg
Pancreatic Cancer, Sepsis
Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies
The aim of the present prospective study was, first, to verify the correlation between biliary colonization and postoperative infectious complications, and secondarily to asses morbidity and mortality for patients who underwent…
- Conditions
- Pancreatic Cancer, Sepsis, Bile Duct Cancer, Duodenal Cancer
- Trial name
- NCT03525067
- Testing
- Bile sampling for bacterial examination
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Crohn's Fistula
Clinical Study to Evaluate Efficacy and Safety of ASC and Fibringlue or Fibringlue in Patients With Crohn's Fistula
This is a phase III study to evaluate the efficacy and safety of ASC(Autologous Adipose-derived Stem Cells) and Fibringlue or Fibringlue in Patients With Crohn's Fistula.
- Trial name
- NCT04612465
- Testing
- ASC, Fibringlue
- Where
- 4 sites in South Korea
- Volunteers
- 46 people
- Sponsor
- Anterogen Co., Ltd.
Hemodialysis Complication
The Effect of Ice Massage on Pain, Ecchymosis, Hematoma and Patient Satisfaction
The research was planned to measure pain, ecchymosis, hematoma and patient satisfaction with ice massage applied to the fistula before the arteriovenous fistula procedure in hemodialysis patients.
- Trial name
- NCT06332118
- Testing
- ice massage group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Erzurum Technical University
Arteriovenous Fistula Stenosis
AcoArt III / Arterio-venous Fistula in China
This trial is aimed to evaluate the safety and efficacy of DCB in treating AVF stenosis in chinese population.
- Trial name
- NCT03366727
- Testing
- drug-coated balloon catheter （Orchid, Acotec）, plain balloon catheter (Admiral, medtronic)
- Where
- 13 sites in China
- Volunteers
- 244 people
- Sponsor
- Acotec Scientific Co., Ltd
Oroantral Fistula, Double Layer
Double-Layer Closure Technique Using Buccal and Palatal Flaps for Oroantral Fistula
A prospective clinical case series was conducted involving twelve patients with oroantral fistulas ≥5 mm in diameter. Closure was performed using split-thickness buccal and palatal mucosal flaps with a subepithelial palatal…
- Trial name
- OAF-DLC (NCT07196566)
- Testing
- Closure was performed using split-thickness buccal and palatal mucosal flaps with a subepithelial palatal connective tissue graft
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Tanta University
Pancreatic Fistula
Comparison of Effectiveness of TissuePatchTM in Preventing Postoperative Pancreatic Fistula
Postoperative pancreatic fistula is one of the most serious complications after gastric cancer surgery and can lead to surgery-related death.
- Trial name
- NCT05404256
- Testing
- Radical gastrectomy +D2 lymphadenectomy+TissuePatchTM to seal pancreatic tissue surface, Radical gastrectomy +D2 lymphadenectomy
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Hypothyroidism; Surgery, Head and Neck Cancer
Wound Complications in Head and Neck Surgery
This is a prospective observational study evaluating wound complications following head and neck surgery. Patients undergoing major head and neck surgery will be included in the study.
- Conditions
- Hypothyroidism; Surgery, Head and Neck Cancer, Wound Heal, Laryngeal Cancer
- Trial name
- NCT03134976
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Hemodyalysis
AVF-MONITOR POC Proof-of-concept Study
This is a proof-of-concept single-centre prospective longitudinal interventional study performed in AVF patients under HD treatment at the Nephrology and Dialysis Department of the ASST-Papa Giovanni XXIII (Bergamo, Italy)…
- Trial name
- AVFMONITOR POC (NCT07318025)
- Testing
- AVF MONITOR
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
End-stage Renal Disease
Evaluation of the Radial Artery Deviation And Reimplantation Technique for Primary Hemodialysis Access Creation
The Radial Artery Deviation And Reimplantation (RADAR) technique is a new approach for the construction of hemodialysis arteriovenous fistula.
- Trial name
- RADAR (NCT02728817)
- Testing
- End-cephalic vein to side-radial artery fistula creation, RADAR fistula creation
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Transplant;Failure,Kidney, Transplant; Failure, Liver
Abdominal Wall Transplant
The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects.
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect
- Trial name
- NCT03310905
- Testing
- Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Perianal Fistula, Primary; Complex
Follow-up Study of Autologous Adipose-derived Stem Cells (ANTG-ASC) for the Complex Fistula (ANTG-ASC-211)
This is an open follow-up clinical trial to evaluate a sustained efficacy and safety of ANTG-ASC injection for 4 months (6 months after final dose injection) after Phase II clinical trial.
- Trial name
- ANTG (NCT01623453)
- Testing
- Autologous adipose derived stem cells(low dose group), Autologous adipose derived stem cells(high dose group)
- Where
- 2 sites in South Korea
- Volunteers
- 6 people
- Sponsor
- Anterogen Co., Ltd.
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Anal Fistula
Multicenter Prospective Evaluation of Radiofrequency for Anal Fistulas
Anal fistula treatment is associated with increasing risk of anal incontinence until 40% of cases. New and alternative treatments (glue, advancement flap, plug…) decrease this risk, but with fistula efficacy treatment in 40 to…
- Trial name
- RADIOFIST (NCT03131297)
- Testing
- treatment by radiofrequency
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- F Care Systems NV
End Stage Renal Disease
Confirmatory Study to Assess the V Needle in End-Stage Renal Disease Patients During In-Clinic Hemodialysis
This study is a prospective, multi-center, single-arm study with subjects acting as their own control designed to confirm the safety, performance, and usability of the V Needle, a new safety needle for use during in-clinic…
- Trial name
- Clinic-SAVER (NCT05493423)
- Testing
- V Needle AV Fistula Set
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hemotek Medical Inc
Anorectal Fistula
Anal Sphincter Reconstruction After High Recurrent Anorectal Fistula Excision
A retrospective analysis of patients treated for recurrent posterior anorectal fistula, who previously had undergone radical excision of fistula-in-ano, was performed.
- Trial name
- NCT04357210
- Testing
- fistula tract excision and anal sphincter reconstruction
- Volunteers
- 14 people
- Sponsor
- Russian Society of Colorectal Surgeons
Chronic Kidney Disease Requiring Hemodialysis
Creation of Arteriovenous Fistulas for Hemodialysis Using the End-to-side Anastomotic Technique vs. Piggyback.
This study is designed to compare two surgical techniques used to create arteriovenous fistulas (AVFs), which are necessary for hemodialysis in patients with advanced chronic kidney disease (CKD).
- Trial name
- NCT06997042
- Testing
- Terminolateral anastomotic technique, Piggyback anastomotic technique
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Hospital Clinic of Barcelona
Renal Dialysis
Pain Perception by the Chronic Renal Patient at the Time of Vascular Access Cannulation.
Pain in patients under hemodialysis affects chronic renal patients' quality of life. Distraction has been effective in controlling pain induced by the insertion of needles.
- Trial name
- NCT05729113
- Testing
- Distraction technique
- Where
- Portugal
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Joana Sofia Dias Pereira de Sousa
Crohn Disease, Anal Fistula
Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem Cells
One of the newest and most innovative medicinal approaches is cell therapy. Several clinical trials and experimental investigations have looked into the feasibility of treating CD-related fistulas with stem cells.
- Trial name
- CHAZAM (NCT05974280)
- Testing
- Alofisel, Fat stem cell
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Nantes University Hospital
Arteriovenous Fistula
Pre-Operative Forearm Exercise On Arteriovenous Fistula Mauration
To investigate the effect of pre-operative exercise on 1. Hemodynamics in the fistula artery and vein, pre and post AV fistula formation 2. Suitability of cannulation of AV fistula at 8weeks
- Trial name
- NCT03137680
- Testing
- Hand Exercise
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital