Clinical trials: Fertility Issues
Unexplained Infertility, Recurrent Implantation Failure
Using Microfluidic Separation Sperm Selection for Unexplained Infertility and Reccurrent Implantation Failure
In order to increase the likelihood of achieving IVF-treated pregnancy, good quality embryo transfer is important. To get good quality embryos, good quality gametes are needed.
- Trial name
- NCT03355937
- Testing
- Sperm Chip
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infertility
Prospective Observational Study of Peri-implantation Serum hCG Levels
The purpose of this study is to prospectively define a set of data suitable for developing models of pregnancy viability. Those models will be based on serum hCG concentration measured during the peri-implantation period in…
- Trial name
- NCT01184469
- Where
- United States
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Fertility Issues
The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.
In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes.
- Trial name
- NCT06156722
- Testing
- Sperm selection by IMSI, Sperm selection by IMSI and spermslow
- Where
- Israel
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Male Infertility
Oxidative Stress and Lipidomics in Male Infertility
Infertility is a common problem, affecting perhaps one couple in six, the majority of whom now seek medical care. It is becoming a social challenge because it is responsible for personal and interpersonal discomfort and anxiety.
- Trial name
- NCT02062229
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Spermatogenesis and Semen Disorders, Infertility, Male
Power Prenatal Supplements for Sperm Quality
Male factor infertility is a leading cause of primary and secondary infertility. Poor sperm quality is defined as having an abnormal semen analysis [WHO 2020 - https://www.who.int/publications/i/item/9789240030787].
- Trial name
- NCT05410782
- Testing
- Power Prenatal for Sperm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Bird and Be Co Inc
Non Specific Chronic Endometritis, Infertility, Female
Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis
Infertile women undergoing hysteroscopy for diagnostic or therapeutic indication are asked to donate a sample of endometrium. Endometrial samples of study participants are examined for signs of chronic endometritis by…
- Trial name
- endoMB (NCT04103242)
- Testing
- 16s rRNA gene sequencing
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Total Shoulder Arthroplasty, Shoulder Infection
Surgiphor Us in TSA
Bacteria is occasionally present in the shoulder during shoulder arthroplasty surgery and is hypothesized to increase the risk of failure of the prosthesis.
- Conditions
- Total Shoulder Arthroplasty, Shoulder Infection, Povidone Iodine
- Trial name
- NCT06601803
- Testing
- sterile saline solution, Surgiphor, Sample Collection
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Healthy Volunteer Study
An Investigation to Evaluate Wearing Properties of Three Different Investigational Devices
This clinical investigation will assess the self-adhesive properties of two investigational devices compared to a test specimen reference.
- Trial name
- NCT07034014
- Testing
- Dressing
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Molnlycke Health Care AB
Childbearing, Delayed, Marriage Age
Youth Outlook on Life Opportunities Study
Singapore's fertility rate is currently below 1.2, raising concerns about population ageing and long-term sustainability. The fertility decline is characterized by falling birth rates among women in their 20s with almost no…
- Conditions
- Childbearing, Delayed, Marriage Age, Educational Problems, Anxiety
- Trial name
- NCT05026619
- Testing
- Information about age-related fertility, Information about policy initiatives, Information about diabetes
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Infertility, Female
Laparoscopy in Failed IVF
Current in-vitro fertilization (IVF) consumers are enjoying better success rates than early seekers, but only about a quarter of IVF cycles result in a live birth and many patients remain infertile after multiple IVF attempts.
- Trial name
- NCT06165484
- Testing
- laparoscopy and hysteroscopy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
Follicular Flushing Versus Direct Aspiration
The purpose of this study is to investigate the impact of follicular flushing on the oocyte recovery rate, oocyte maturity, fertilization rate, and embryo development and utilization as compared to direct aspiration (no flushing)…
- Trial name
- NCT03354858
- Testing
- Follicular flushing
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility, Female
Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness
One hundred thirty women with unexplained infertility participated in a prospective clinical study. Patients were assigned at random to one of two groups.
- Trial name
- NCT05846906
- Testing
- Sildenafil Citrate, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Infertility
Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist
rFSH and HMG are both used to controlled ovarian stimulation for patients submitted to IVF. However, there is a debate in the literature which one is better to induce ovulation in patients receiving GnRH antagonist to block…
- Trial name
- NCT02412904
- Testing
- rFSH, HMG
- Where
- Brazil
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Male Infertility, Azoospermia, Nonobstructive
Management of Non Obstructive Azoospermia in Men
this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility
- Trial name
- azoospermia (NCT06983626)
- Testing
- micro-dissection testicular sperm extraction
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Valley University
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Infertility, Female
Topical Analgesia for Pain Relief in Hysterosalpingography
The study will involve giving topical analgesia or placebo and then assessing pain and satisfaction during and after the procedure in order to see wed to the placebo.hether the topical analgesia has helped in decreasing pain…
- Trial name
- HSG (NCT03802032)
- Testing
- Lidocaine Gel, KY jelly
- Where
- Nigeria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Healthy Women, Infertility, Female
Assess the Effect of Dehydroepiandrosterone (DHEA) or Other Androgenic Agents Over Markers of Ovarian Reserve
This study was conducted to evaluate the effect of a continuous administration of dehydroepiandrosterone (DHEA) or other androgenic agents on ovarian reserve markers in women with diminished ovarian reserve (ROD), such as antral…
- Trial name
- NCT02268032
- Testing
- DHEA, Another Androgenic Agent (VRaA), Fixed combination of 2 androgenic agents (VR2A)
- Where
- Chile
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Infertility
Effects of Intrauterine Administration of Autologous PBMC Modulated With IFNt on Endometrial Cell Populations
The aim of this clinical trial is to investigate the change in endometrial composition during the window of implantation following intrauterine administration of PBMC immunomodulated with IFNt.
- Trial name
- NCT05775211
- Testing
- Intrauterine administration of PBMC immunomodulated with IFNt
- Where
- Bulgaria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nadezhda Women's Health Hospital
Skin Sterility After Use of Ethyl-chloride Spray.
Skin Sterility After Ethyl-Chloride Spray
The aim of this study is to investigate sterility of ethyl-chloride topical anesthetic spray when used prior to an injection. The hypothesis is that the spray does not change the sterility of the injection site after skin is…
- Trial name
- NCT01292850
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
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