Clinical trials: Fatty Acids
Prostate Cancer
Study Evaluating the Correlation Between C-11 Acetate Uptake and Retention as Measured by PET and FAS in Prostate Cancer
The purpose of this study is to understand if a new type of radiology test called positron emission tomography (PET) with carbon 11 acetate will help us to understand which cancers produce more of a protein called fatty acid…
- Trial name
- NCT00139191
- Testing
- C-11 acetate PET scan
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Healthy
Effects of Omacor and Aspirin on Platelet Function
Omacor (now Lovaza) is a pharmaceutical omega-3 fatty acid product. Omega-3 fatty acids can affect blood clotting by altering the function of the blood platelets. Aspirin can do the same.
- Trial name
- NCT00688961
- Testing
- Aspirin, omega-3 acid ethyl esters
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sanford Research
Dyslipidemia
Effect of Plant Sterols Esterified to Fish Oil Fatty Acids on Plasma Lipid Levels
The purpose of this study is to determine whether plant sterols esterified to fish oil fatty acids in a fish oil matrix improve the lipid profile, predominantly LDL-cholesterol and TG concentrations in healthy hyperlipidemic…
- Trial name
- NCT00441480
- Testing
- Plant sterols esters
- Where
- Israel
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Enzymotec
Non-alcoholic Fatty Liver Disease
Runihol in Nonalcoholic Fatty Liver Disease and Metabolic Syndrome
The study is designed to assess the safety and efficacy of different doses and dosing regimens of Runihol, tablets, enteric coated, produced by "NTFF" POLYSAN" (Russia), in prevention of liver disease progression in patients with…
- Trial name
- NCT02930161
- Testing
- Runihol
- Where
- 3 sites in Russia
- Volunteers
- 35 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Obesity, Aging
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids.
Dysfunction of adipose tissue in obesity, inflammation and aging: mechanisms and effects of physical exercise and omega-3 fatty acids.
- Conditions
- Obesity, Aging, Inflammation
- Trial name
- OBELEX (NCT03300388)
- Testing
- Omega-3 (DHA-rich dietary supplement), Resistance training
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Non-Alcoholic Fatty Liver Disease
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study
Over the past 30 years, the prevalence of childhood obesity in the United States has tripled from 5% to 15%. Major consequences of obesity include insulin resistance, type- 2 diabetes, cardiovascular disease and nonalcoholic…
- Trial name
- NCT01285362
- Testing
- Fish Oil Supplementation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
Type 2 Diabetes
The Acute Effect of Low-carb Diet on the Plasma Fatty Acid Composition in Type 2 Diabetes
The investigators wishes to investigate the acute effect of a low carbohydrate meal on the plasma fatty acid (FA) composition compared with a control meal in a cross-over study of patients with type 2 diabetes (T2D).
- Trial name
- NCT05498688
- Testing
- Low carbohydrate
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Type 2 Diabetes
n-3 Fatty Acid Infusion and Type 2 Diabetes
The purpose of this experimental study is to investigate whether an acute lipid infusion added marine n-3 fatty acids produces effects on insulin sensitivity in subjects with type 2 diabetes, when compared with an acute lipid…
- Trial name
- NCT00829569
- Testing
- Intralipid +/- Omegaven
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- St. Olavs Hospital
Lifestyle
Omega-3 Bioavailability From Vegetable-omega-3 Enriched Products
CSIRO's Food Program has developed a novel vegetable-based Omega-3 long-chain polyunsaturated fatty acid (Omega 3)encapsulant to be used as ingredient in various food products, however, it is unknown whether the vegetable-based…
- Trial name
- NCT04610983
- Testing
- Experimental: Control, Experimental: Treatment 1 - Semi-Solid food matrix, Treatment 2 - Solid food matrix
- Where
- 2 sites in Australia, Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Commonwealth Scientific and Industrial Research Organisation, Australia
Chronic Renal Failure
Effect of Omega 3 Fatty Acids on the Vascular Calcification Biomarkers Fetuin A and Osteoprotegerin in Patients With CRF
study the effect of omega 3fatty acids on the vascular calcification biomarkers Fetuin -A and Osteoprotegerin (OPG) in dialysis patients.
- Trial name
- CRF (NCT03982966)
- Testing
- Omega 3 fatty acids (fish oil) 1000 mg/day oral
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour University
n-3 Polyunsaturated Fatty Acids
N-3 Polyunsaturated Fatty Acids Enriched Chicken Meet and Cardiovascular Function
Evidence from multiple experimental, epidemiological, and clinical studies indicate that n-3 polyunsaturated fatty acids (n-3 PUFAs) may exert their cardiovascular (CV) protective effect, at least in part, by improving vascular…
- Trial name
- NCT05725486
- Testing
- N-3 PUFAs Chicken Meet, Regular Chicken Meet
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Moderate Hypertriglyceridemia.
Lovaza Mechanisms of Action
High levels of triglycerides is a common abnormality found in patients with diabetes and also cardiovascular disease, and may contribute to the risk for both.
- Trial name
- NCT01301794
- Testing
- Omega 3 fatty acid (Lovaza)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy
Effect of Docosa-Hexanoic Acid (DHA) Supplements During Pregnancy on Newborn Outcomes in India.
The 'DHANI randomized controlled trial" seeks to examine the effects of prenatal DHA supplementation on newborn anthropometry where in healthy pregnant will be assigned to receive either 400 mg of DHA or a placebo daily from ≤20…
- Trial name
- DHANI (NCT01580345)
- Testing
- Docosa-hexaenoic acid (DHA)
- Where
- India
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre for Chronic Disease Control, India
Dry Eye Syndrome
Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye
The study evaluates the safety, ocular tolerability and efficacy of emulsion eye drops with sacha inchi seed oil, trehalose and hyaluronic acid in the treatment of moderate or severe dry eye in adult patients.
- Trial name
- NCT03569202
- Testing
- Piiloset Trehalose Emulsion Eye Drops, Control Eye Drops
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Kuopio University Hospital
Unresectable Hepatocellular Carcinoma (HCC), Hepatocellular Carcinoma (HCC)
FAD Subtype-Guided Combination Therapy for Unresectable Hepatocellular Carcinoma
This study is a prospective, multicenter Phase II trial evaluating a personalized treatment strategy for patients with unresectable hepatocellular carcinoma (HCC).
- Conditions
- Unresectable Hepatocellular Carcinoma (HCC), Hepatocellular Carcinoma (HCC), Liver Cancer Adult
- Trial name
- FAD-HCC-001 (NCT07314372)
- Testing
- Camrelizumab Plus Apatinib, TACE Plus Camrelizumab and Apatinib
- Where
- China
- Volunteers
- 86 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Cardiovascular Disease
Effect of Trans Fatty Acids From Ruminant Sources on Risk Factors for Cardiovascular Disease
The objectives of this study are to : 1) determine if vaccenic acid (trans-11-octadecenoic, a naturally occurring trans fatty acid isomer from ruminant animal products) raises LDL cholesterol in a quantitatively comparable manner…
- Trial name
- NCT00942656
- Testing
- PHVO, CLA, VA
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Crohn Disease
The Effects of Parenteral ω-3 Polyunsaturated Fatty Acid on Postoperative Complications of Patients With Crohn's Disease
This study is intended to investigate the safety and efficacy of ω-3 polyunsaturated fatty acid-based parenteral nutrition (PN) for patients with Crohn's disease.
- Trial name
- ω3CD (NCT03901937)
- Testing
- ω-3 polyunsaturated fatty acid, Intestinal surgery for Crohn's Disease
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Sir Run Run Shaw Hospital
Obesity
Obesity and Fatty Acid Flux Comparison Trials
This study will explore factors that affect obesity and obesity-related diseases in both Caucasians and African Americans. By looking at the rate at which the human body burns calories while at rest (resting energy expenditure…
- Trial name
- NCT00074945
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammation
Maqui Berry Extract and Omega-3 Fatty Acids for Cytokine Reduction
The purpose of this trial is to determine the effect of maqui extract plus omega-3 fatty acids compared to a placebo for reducing inflammatory cytokine levels in older, obese adults.
- Trial name
- NCT04914312
- Testing
- Maqui berry/omeg-3 fatty acids
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hypertriglyceridemia
Evaluation of the Efficacy of Phospholipid-Bound Omega-3 Versus Omega-3 Alone in Patients With Hypertriglyceridemia: A Randomized Clinical Trial
Hypertriglyceridemia is a significant risk factor for cardiovascular diseases. Omega-3 fatty acids have been shown to reduce triglyceride levels, and their combination with phospholipids could offer additional benefits in…
- Trial name
- OMEGA-PHYT (NCT06749028)
- Testing
- Intervention Arm: Omega-3 + Phospholipids., Comparator Arm: Omega-3 alone.
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación del Caribe para la Investigación Biomédica
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