Clinical trials: Eye Disease; Cataract
Congenital Cataract
Capsulorhexis Size and Capsular Outcome
Different capsulorhexis size results in different capsular outcome when treating pediatric cataract, and there should be an appropriate capsulorhexis size for the best capsular outcome.
- Trial name
- NCT02158325
- Testing
- anterior capsulorhexis sizes
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Sun Yat-sen University
Patients' Information Level About Cataract Surgery, Patients' Attitude Before and After Cataract Surgery
Computer-based Tutorial as a Means to Enhance the Informed Consent Process for Cataract Surgery
Informing the patient and obtaining the informed consent is one of the major duties physicians perform before beginning a medical treatment.
- Trial name
- NCT07167576
- Testing
- Catinfo tool and discussion with physician, discussion with physician
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery
This randomized controlled trial compares two regimens of topical therapy: tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon)…
- Trial name
- NCT00992355
- Testing
- Tobramycin 0.3% - Dexamethasone 0.1%, Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
- Where
- Greece
- Volunteers
- 97 people
- Sponsor
- Veroia General Hospital
Age Related Cataracts, Astigmatism
Femtosecond Laser-assisted Astigmatism Treatment
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure including arcuate incisions (AI) correcting astigmatism, also referred…
- Trial name
- FLAAT (NCT04321226)
- Testing
- Femtosecond Laser guided Arcuate Keratotomy
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Medical University of Vienna
Cataract
Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL
Comparison of postoperative visual acuity and spectacle independence between the Tecnis Multifocal Intraoculer Lens (IOL) and the crystalens Accommodating IOL
- Trial name
- NCT01275118
- Testing
- Tecnis Multifocal IOL, crystalens Accommodating IOL
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mark Packer, MD, FACS
Ocular Inflammation and Pain After Cataract Surgery
A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of APP13007 to Treat Inflammation and Pain After Cataract Surgery
This is a Phase 2a, 2-part study (designated Parts A and B) that will evaluate APP13007 dose strength and dosing frequency in a randomized double-masked fashion for comparison to the respective matching vehicle placebo.
- Trial name
- NCT04089735
- Testing
- APP13007, 0.05%, APP13007, 0.1%
- Where
- 9 sites in United States
- Volunteers
- 165 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Senile Cataract
VRQOL in Cataract Patients During the COVID-19 Pandemic
The aim of this questionnaire survey is to evaluate the improvement in vision-related quality of life before and after cataract surgery using the National Eye Institute Visual Function Questionnaire 25 and the delay of…
- Trial name
- NCT04468308
- Testing
- Questionnaire
- Where
- Austria
- Volunteers
- 116 people
- Sponsor
- Medical University Innsbruck
Diabetic Macular Edema
IVI Aflibercept Before and After Phaco in DME.
To study whether or not cataract surgery should be deferred until treating the co-existing diabetic macular edema (DME) using intravitreal (IVI) anti-vascular endothelial growth factor (anti-VEGF).
- Trial name
- NCT05731089
- Testing
- Phacoemulsification with IVI of aflibercept
- Where
- Kuwait
- Volunteers
- 40 people
- Sponsor
- Al Hadi Hospital
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract
Tunnel Construction Course Pilot Assessment of Simulation-based Training Effectiveness
TCC-PASTE is a randomised controlled trial comparing a simulation based training curriculum with standard training for ophthalmology residents learning to perform tunnel construction in manual small incision cataract surgery.
- Trial name
- TCC-PASTE (NCT04450420)
- Testing
- Simulation based curriculum, Standard training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- HelpMeSee Inc.
Cataract; Complicata, Posterior Capsule Tear
CT Lucia 601 IOL Implantation in the Sulcus
To perform a retrospective investigation of the CT Lucia 601 IOL implantation in the sulcus
- Conditions
- Cataract; Complicata, Posterior Capsule Tear, Lens Dislocation
- Trial name
- CLUS (NCT04796662)
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Cataract
Zeiss® IOLMaster 700 Corneal Topography Module Comparison With Schwind's Sirius Corneal Topography®
In order to determine the intraocular lens to be implanted during cataract surgery, keratometry and axial length must be measured in preoperative. The axial length is obtained by ocular ultrasound mode B.
- Trial name
- VIMECT (NCT05414773)
- Testing
- measurement of axial length and keratometry by sonographers with a topographic module
- Volunteers
- 100 people
- Sponsor
- Edouard KOCH
Cystoid Macular Edema, Postoperative, Diabetes Mellitus
Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients
The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract…
- Trial name
- NCT02646072
- Testing
- Ketorolac tromethamine ophthalmic solution 0.45%
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Intraocular Foreign Body
Extraction Routes of Intraocular Foreign Body
Intra ocular foreign body removal is indicated to avoid further many complications such as retinal detachment, endophthalmitis. The surgical approach for a posterior segment IOFB is pars plana vitrectomy and its extraction either…
- Trial name
- IOFB (NCT05966545)
- Testing
- pars plana vitrectomy and intraocular foreign body removal
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Diabetes, Macular Edema
Analysis of the Effect of Intravitreal Dexamethasone Injection on Diabetic Macular Edema After Cataract Surgery (IDDMECS)
Macular Edema (Swelling of a particular site of the retina) can become a significant problem for Diabetics undergoing Cataract surgery. And a significant number of people who undergo Cataract surgery each year are diabetics.
- Conditions
- Diabetes, Macular Edema, Pseudophakia
- Trial name
- IDDMECS (NCT01030601)
- Testing
- Dexamethasone sodium phosphate
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.