Clinical trials: Exercise Response
Obesity, Metabolically Healthy Obesity
Exercise and Diet Responses in Adult Men With Obesity by MC4R Genotype and Metabolic Health
This study evaluated whether differences in the MC4R rs17782313 gene variant and metabolic health status were associated with different responses to a 12-week exercise and dietary intervention in adult men with obesity.
- Conditions
- Obesity, Metabolically Healthy Obesity, Metabolically Unhealthy Obesity
- Trial name
- NCT07750197
- Testing
- Supervised Aerobic and Resistance Exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Harbin Sport University
Inactivity, Physical
The Effects of One Day of Activity on the Next Day's Exercise Response
Exercise can reduce the risk of several chronic diseases. However, recent studies have suggested sitting for too long before exercising can decrease exercise benefits. This study will help determine why this may occur.
- Trial name
- NCT07429370
- Testing
- Decreased step count
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Soccer Training, Body Composition
The Influence of Football Training as a medicine_FIM_UTH
The purpose of this randomized controlled study will be to inestigate the relationship between recreational football training at various training volumes and the health responses of middle-aged participants at high risk for…
- Conditions
- Soccer Training, Body Composition, Physical Activity, Healthy
- Trial name
- FIM (NCT05273203)
- Testing
- FIM-1, FIM-2, FIM-3
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Intermittent Inspiratory Muscle Training, Eupnea
Effects of Inspiratory Muscle Exercise on Health
The purpose of this study is to investigate whether inspiratory muscle training has an immediate effect on energy expenditure, heart rate, blood glucose, blood pressure, and arterial stiffness in healthy adults, obese adults, and…
- Trial name
- NCT07095179
- Testing
- Eupnea, Intermittent inspiratory muscle training (IIMT)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Low Back Pain
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic…
- Trial name
- NCT05156242
- Testing
- Active-tDCS priming MCE, NMES priming MCE, Conventional physical therapy
- Where
- Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypoxia, Altitude Sickness
Cardio-respiratory Responses During Hypoxic Exercise in Individuals Born Prematurely
This project will consist of two studies, each investigating resting and exercise cardio-respiratory responses during exposure to hypoxia in individuals born prematurely and individuals born at full term of two different age…
- Conditions
- Hypoxia, Altitude Sickness, Tolerance
- Trial name
- PreTerm (NCT02780908)
- Testing
- Graded exercise testing, Resting testing
- Where
- 2 sites in Slovenia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Jozef Stefan Institute
Diabetes Mellitus, Type 2, Aerobic Exercise
The Effect of Aerobic Exercise on Genetic Molecules
The aim of this study is to compare the effects of high intensity interval exercise and moderate intensity continuous exercise on some genetic molecules in patients with type 2 diabetes mellitus.
- Conditions
- Diabetes Mellitus, Type 2, Aerobic Exercise, Genetic Response
- Trial name
- xnx (NCT04181853)
- Testing
- exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Pamukkale University
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Pulmonary Arterial Hypertension
Utility of At-home Monitoring of Exercise Capacity by App-based 6-minute Walk Test
Evaluate for accuracy and reproducibility of data collected via the participant-operated Walk.Talk.Track. (WTT) app combined with Apple Watch during in-clinic, technician proctored 6MWT's.
- Trial name
- DynAMITE (NCT03893500)
- Testing
- Home-based 6 minute walk test
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stanford University
Parkinson Disease
To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study
This is a prospective, observational, cohort pilot study of standardize volume of aerobic exercise on changes in BDNF concentration at 4-weeks of exercise training among Parkinson disease patients.
- Trial name
- METEX-PD (NCT06339398)
- Testing
- Aerobic exercise
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Healthy Aging
Effects of a Recreational Team Handball-based Programme on Health and Physical Fitness of Middle-aged and Older Men
The present study aims at analyzing the dose-response effects of a recreational team handball-based exercise programme on cardiovascular, metabolic, musculoskeletal and physical fitness markers of inactive middle-aged and older…
- Trial name
- (H4HM) (NCT05295511)
- Testing
- Recreational Team Handball programme
- Where
- Portugal
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Institute of Maia
Cardiovascular Risk
Dose-Response to Resistance Exercise on Cardiovascular Health
A large body of evidence indicates numerous health benefits of physical activity, including prevention of cardiovascular disease (CVD), the leading cause of death in the US.
- Trial name
- DoReps (NCT06619444)
- Testing
- Aerobic exercise only, 30 min of resistance exercise, 60 min of resistance exercise
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Pittsburgh
Cardiovascular Fitness
Physiological and Perceptual Responses During 4-Second Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses.
- Trial name
- NCT06912932
- Testing
- Preventive
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Cardiovascular Diseases
Fat Metabolism in Response to Acute Diet- and Exercise-induced Changes in Energy Balance
This study is being conducted to learn more about the role of diet and exercise in regulating plasma triglyceride (fat) metabolism.
- Trial name
- DEV (NCT00830999)
- Testing
- Positive energy balance, Energy balance with exercise, Negative energy balance
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Spinal Cord Injuries, Cardiovascular Diseases
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept
As compared to the general population, those living with a spinal cord injury (SCI) are at a greater risk of cardiovascular (CV) diseases.The investigators know that regular exercise can help lessen the risk of CV diseases.
- Conditions
- Spinal Cord Injuries, Cardiovascular Diseases, Health Behaviour, Physical Inactivity
- Trial name
- NCT06027502
- Testing
- Passive Heating
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Physiological Stress, Heat Stress
Validation of Heat Stress Limit Values for the Athletic Performance
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses.
- Conditions
- Physiological Stress, Heat Stress, Sports Injury, Heat Stress, Exertional
- Trial name
- HSL-AP (NCT06084494)
- Testing
- analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature
- Where
- Pakistan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Muscle Fatigue
Microcurrent Therapy and the Post-Exercise Physiological Response (MENS_PE)
The goal of this clinical trial is to find out whether microcurrent therapy changes blood levels of creatine kinase, a marker of muscle stress, during the first 48 hours after exercise in military personnel.
- Trial name
- MENS_PE (NCT07877337)
- Testing
- Microcurrents Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Brain Hypoxia, Hypoxia
Cerebral Responses During Exercise in Hypoxia
While the exercise responses are classically described at the cardiorespiratory and muscle levels, recent data suggest that the brain is also significantly stressed by exercise and may even participate to performance limitation.
- Trial name
- CERVOX (NCT01614119)
- Testing
- Hypoxic exposure
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Early Breast Cancer, Neoadjuvant Treatment
Impact of "Targeted" Nutritional Apport and Exercise on the Modulation of Metabolic and Immune-related Gene Expression Signatures in Early Breast Cancer (eBC) Patients Candidate to Neoadjuvant Therapy (NAT)
NEOMET is an exploratory randomized prospective, multicenter study whose primary aim is to explore if metabolomic signatures can be modified by a lifestyle intervention including dietary supplements and physical exercise…
- Trial name
- NEOMET (NCT06928701)
- Testing
- omega-3 (n-3 Lc-PUFA), EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) plus a source of palmitoleic acid (hexadecenoic acid)
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Eastern Piedmont
Physical Inactivity, Overweight or Obesity
eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06570642
- Testing
- Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Southern California