Clinical trials: Eustachian Tube Dysfunction
Eustachian Tube Dysfunction, Hearing Disorders
FFP3 Respirators and Ears - Effects on Middle Ear Pressure and Hearing
This is Prospective Basic Science Study whose aims are as follows: 1. To determine the effect of Filtering Facepiece (FFP3M) respirators on eustachian tube function and hearing 2.
- Conditions
- Eustachian Tube Dysfunction, Hearing Disorders, Nasal Obstruction
- Trial name
- FFP3-RAE (NCT05222230)
- Testing
- FFP3 Mask
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Retraction of the Pars Tensa of the Tympanic Membrane, Eustachian Tube Dysfunction
Feasibility Study of Balloon Eustachian Tuboplasty (BET)
This is a study that aims to evaluate the feasibility of undertaking a United Kingdom (UK) multi-centre randomised controlled trial of BET for the treatment of moderate (grade 2 or 3) retraction pockets (RPs).
- Conditions
- Retraction of the Pars Tensa of the Tympanic Membrane, Eustachian Tube Dysfunction, Retraction Pocket of the Tympanic Membrane
- Trial name
- BET (NCT02631187)
- Testing
- Bielefeld balloon
- Where
- United Kingdom
- Sponsor
- University Hospital Plymouth NHS Trust
Eustachian Tube Dysfunction, Laryngopharyngeal Reflux
The Study of Eustachian Tube Dysfunction and Laryngopharyngeal Reflux
The purpose of this study is to investigate the relationship between ear fullness, pressure, and/or pain and laryngopharyngeal reflux, in order to focus medical therapy and improve therapeutic outcomes in this patient population.
- Trial name
- ETDLPR (NCT02123498)
- Testing
- Omeprazole, Ranitidine, Pantoprazole
- Where
- 2 sites in United States
- Sponsor
- Loma Linda University
Eustachian Tube Dysfunction
Pretympanoplasty Assessment of Patency and Mucociliary Function of Eustachian Tube
The eustachian tube (ET) performs three primary functions: pressure equalisation between the nasopharyms and middle ear: clearance of mucus from the middle ear, and prevention of sound or fluid reflux from the nasopharynx(1) .In…
- Trial name
- NCT05229380
- Testing
- Saccharin test
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Eustachian Tube Dysfunction
Tubomanometry and EarPopper Devices for Eustachian Tube Function Testing
The Eustachian tube (ET) is a biological tube that links the middle ear to the back of the nose and throat. It has several functions, of which the most important is to maintain optimal middle-ear health.
- Trial name
- NCT03850197
- Testing
- EarPopper, Tympanometry, Tubomanometry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cuneyt M. Alper
Eustachian Tube Dysfunction
Balloon Dilation of the Eustachian Tube
In this study, patients with dysfunction of the eustachian tube will be included. They will be randomized to one of two treatment groups. 1. balloon dilation of the eustachian tube or 2.
- Trial name
- BDET (NCT05270031)
- Testing
- Balloon dilation of the eustachian tube
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Otits Media With Effusion
Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial
Brief Summary - OMENUTS Trial Otitis media with effusion (OME) is a condition in which fluid accumulates in the middle ear, causing conductive hearing loss, ear fullness, tinnitus, and Eustachian tube dysfunction.
- Trial name
- OMENUTS (NCT07721610)
- Testing
- Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Intranasal mometasone furoate spray
- Where
- Italy
- Volunteers
- 501 people
- Sponsor
- Isola Tiberina - Gemelli Isola Hospital, Rome, Italy
Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Both Ears
Eustachian Tube Dilation With an Endovascular Balloon
The Eustachian tube is a narrow tube which links the back of the nose to the middle ear. Eustachian tube dysfunction may occur when the mucosal lining of the tube is swollen, or does not open or close properly.
- Trial name
- NCT04809753
- Testing
- Eustachian tube dilation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media
Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction
The prevalence of Eustachian tube (ET) dysfunction in adults reaches 1%. It causes a feeling of fullness in the ear, otalgia and hearing loss and can lead to recurrent acute otitis media, development of chronic otitis media with…
- Conditions
- Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media, Effusion After Tympanostomy
- Trial name
- NCT03556215
- Testing
- Eustachian tube dilatation device, Myringotomy
- Where
- 2 sites in Czechia
- Volunteers
- 55 people
- Sponsor
- University Hospital Ostrava
Chronic Eustachian Salpingitis
Feasibility of Balloon Dilation of the Eustachian Tubes Under Local Anesthesia
The objective of this study is to demonstrate that balloon dilation of the Eustachian tubes can be done successfully for treatment of chronic dilatory Eustachian tube dysfunction under local anesthesia with acceptable patient…
- Trial name
- NCT04055714
- Testing
- Balloon dilation of the Eustachian tubes
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Piedmont Ear, Nose, Throat and Related Allergy, PC
Cleft Palate, Tube Disorders Eustachian
Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate
Elevation of the soft palate (the soft part of the roof of the mouth) during swallowing helps the Eustachian tube to open and keep the ear healthy.
- Conditions
- Cleft Palate, Tube Disorders Eustachian, Velopharyngeal Incompetence Due to Cleft Palate, Velopharyngeal Insufficiency
- Trial name
- NCT03868891
- Testing
- EMST150
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Noel Jabbour
Eustachian Tube Dysfunction
Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
The aim of this study is to determine which of the many Eustachian tube function tests (or combination of tests) is most helpful in finding out what is causing ear problems in children and adult patients with middle-ear diseases…
- Trial name
- NCT01974726
- Testing
- ET Stress test, Sonotubometry, Forced Response Test (FRT)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Eustachian Tube Dysfunction
XprESS Eustachian Tube Dilation Study
Study to assess the safety and efficacy of the XprESS device for transnasal Eustachian tube dilation.
- Trial name
- NCT02391584
- Testing
- XprESS, Control
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Entellus Medical, Inc.
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Eustachian Tube Dysfunction
Correlation Analysis Between ETF and Prognosis of Tympanoplasty
The regular opening of the eustachian tube plays an important role in maintaining normal pressure in middle ear cavity, hearing function and preventing the occurrence of middle ear inflammation.
- Trial name
- NCT03424369
- Testing
- Tympanoplasty
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Barotrauma;Ear, OME - Otitis Media With Effusion
Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
A prospective, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula iontophoresis and tube delivery systems for adults in an office setting.
- Conditions
- Barotrauma;Ear, OME - Otitis Media With Effusion, AOM - Acute Otitis Media, Eustachian Tube Dysfunction
- Trial name
- ADEPT (NCT03197558)
- Testing
- Tymbion Iontophoresis and Tube Delivery System (TDS)
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tusker Medical
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
Autoinflation as a Eustachian Tube Rehabilitation
This randomized controlled trial evaluated the effectiveness of autoinflation in preventing recurrence of otitis media with effusion (OME) and reducing the need for reoperation after tympanostomy tube (TT) extrusion in children.
- Trial name
- NCT07122999
- Testing
- Eustachi
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Pusan National University Hospital
Eustachian Tube Dysfunction
Eustachian Tube Dysfunction Assessment
The purpose of the study is to understand the exact mechanism of the activity of paratubal muscles in opening eustachian tube in patients with the functional eustachian tube and those with the eustachian tube dysfunction problem.
- Trial name
- ETDA (NCT02667301)
- Testing
- EMG recording, Tympanic Cavity Air Exchange Test, Tympanometer test
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stratejik Yenilikci Girisimler Ltd.
Glue Ear, Tube Disorders Eustachian
Balloon Dilation of the Eustachian Tube in Children
Otitis media with effusion (OME) is very common in children and characterized by fluid in the middle ear without signs or symptoms of acute ear infection. Treatment options are tympanostomy tubes and/or adenoidectomy.
- Trial name
- NCT03499015
- Testing
- Balloon Eustachian Tuboplasty (BET)
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Otitis Media, Serous, Negative Middle Ear Pressure
Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays
We hypothesize that intranasal steroid application will have a beneficial therapeutic effect in adults with regard to resolution of serous otitis media and/or negative middle ear pressure, as compared to placebo.
- Conditions
- Otitis Media, Serous, Negative Middle Ear Pressure, Rhinitis, Otitis Media With Effusion
- Trial name
- NCT00279916
- Testing
- Triamcinolone acetonide nasal spray
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Mayo Clinic