Clinical trials: Erectile Function
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Male Erectile Disorder, Prostate Cancer
L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors
RATIONALE: L-arginine supplements may improve the quality of life and erectile function in men who are prostate cancer survivors.
- Conditions
- Male Erectile Disorder, Prostate Cancer, Radiation Toxicity
- Trial name
- NCT01105130
- Testing
- Oral L-Arginine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Wake Forest University Health Sciences
Prostatectomy
Intra-operative Assessment of Cavernosal Nerve Stimulus Threshold
Erectile dysfunction persists in approximately 80% of men 1 year after prostatectomy. Various erectile rehabilitation strategies have not provided benefit.
- Trial name
- NCT03150758
- Testing
- 10Hz + 100 micro-seconds, 10Hz + 200 micro-seconds, 7Hz + 100 micro-seconds
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Case Comprehensive Cancer Center
Erectile Dysfunction, Sexual Dysfunction, Physiological
Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
A study to assess the efficacy of vardenafil, taken as a tablet both nightly or 'as needed' (immediately before intended sexual activity) compared to placebo, to evaluate its tolerability and if it can help in recovery of…
- Trial name
- NCT00492635
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 86 sites in United States, Austria and 13 more
- Volunteers
- 628 people
- Sponsor
- Bayer
Prostate Cancer, Erectile Dysfunction
The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy
Despite technological advances, incontinence and impotence remain significant side effects of radical prostatectomy (RP). Strategies have been developed to reduce the injury to the erection nerves (i.e.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Urinary Incontinence
- Trial name
- NCT04577222
- Testing
- Technical modification during radical prostatectomy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Rectal Cancer, Erectile Dysfunction
Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery
Erectile dysfunction (ED) is one of the commonest complications in men after rectal cancer treatment. The purpose of this study is to assess the safety and efficacy of autologous bone marrow mononuclear cells (BMMCs) or…
- Trial name
- NCT02648386
- Testing
- Laparoscopic surgery, NeuroRegen scaffold transplantation, NeuroRegen scaffold/BMMCs transplantation
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Chinese Academy of Sciences
Erectile Dysfunction Due to Arterial Insufficiency
Platelet-rich Plasma (PRP) Injection for Treatment of Erectile Function
The primary objective of the present study is to investigate and compare the treatment efficacy of PRP injection vs placebo treatment in men with mild-moderate vasculogenic ED, as measured by IIEF.The secondary objective of the…
- Trial name
- NCT04050020
- Testing
- Platelet-Rich Plasma (PRP), Normal saline injection
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Erectile Dysfunction
BAY38-9456, 5/10/20mg, vs.Placebo in Erectile Dysfunction
Purpose of the study is:- To assess the efficacy and tolerability of vardenafil in male subjects suffering from erectile dysfunction as compared to placebo- To assess the influence of vardenafil on the self-esteem and…
- Trial name
- NCT00665054
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bayer
Prostate Cancer
Androcur Non-interventional Study Among Patients With Carcinoma of the Prostate
Cyproterone acetate (CPA) is a steroidal antiandrogen which has affinity with progesterone and with glucocorticoid receptors. Cyproterone acetate is long-term proven effective treatment of inoperable carcinoma of the prostate.
- Trial name
- ANES (NCT00919022)
- Testing
- Cyproterone Acetate (Androcur, BAY94-8367)
- Where
- Czechia
- Volunteers
- 194 people
- Sponsor
- Bayer
Prostate Cancer, Erectile Dysfunction
Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for Brachytherapy
The purpose of this study is to determine if a combination of neoadjuvant dutasteride and bicalutamide has the same efficacy and less toxicity than standard treatment with an LHRH agonist and bicalutamide for prostate…
- Conditions
- Prostate Cancer, Erectile Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- NCT00866554
- Testing
- administration of a LHRH agonist and Bicalutamide, administration of Bicalutamide, Dutasteride and Tamoxifen
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- CHU de Quebec-Universite Laval
Erectile Dysfunction
Platelet-Rich Plasma Alone Versus PRP Plus Low-Intensity Shock Wave Therapy for Erectile Dysfunction
Erectile dysfunction is a common condition that may result from vascular, neurological, hormonal, psychological, or medication-related factors.
- Trial name
- NCT07783347
- Testing
- Platelet-Rich Plasma, Low-Intensity Extracorporeal Shock Wave Therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Prostate Cancer
Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment
With people living longer after being treated for prostate cancer, quality of life has become a concern when considering the treatment plan.
- Trial name
- VORTEX (NCT07293585)
- Testing
- Neurovascular sparing stereotactic body radiation therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Transgenderism, Erectile Dysfunction
Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender Persons
This study aims to explore sexual satisfaction among transgender men and their partners following the placement of erectile prostheses after phalloplasty.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- NCT06639776
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- University Hospital, Ghent
Impotence, Prostate Cancer
Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy
In this phase II study, an investigative (not approved by the FDA) drug called GPI 1485 is being assessed to see if it can help preserve erectile function after prostatectomy.
- Trial name
- NCT00090376
- Testing
- GPI 1485
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Cardiovascular High-Risk, Chronic Heart Failure
Association of Multiple CardiOvascular Risk Factors and Erectile Function Across Europe
The purpose of the study is to evaluate the influence of cardiovascular risk factors, heart failure and cardiovascular drug therapy on erectile function in cardiovascular high-risk patients.
- Trial name
- AMORE-Eur (NCT00468637)
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Saarland
Erectile Dysfunction
A Study of Tadalafil After Radical Prostatectomy
The study will include patients with localized prostate cancer who experience erectile dysfunction following bilateral nerve-sparing radical prostatectomy.
- Trial name
- REACTT (NCT01026818)
- Testing
- Tadalafil
- Where
- 52 sites in Belgium, Canada and 8 more
- Volunteers
- 583 people
- Sponsor
- Eli Lilly and Company
Prostate Cancer
Change in Penile Length Following Bilateral Nerve-Sparing Radical Prostatectomy
Some men complain of changes in the shape or dimensions of their penis after undergoing radical prostatectomy (removal of the prostate) for prostate cancer. Changes in penile dimensions include shortening or decreased girth.
- Trial name
- NCT00800813
- Testing
- Penile Exam, Peyronie's Plaque and Erectile function assessment
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Erectile Dysfunction (ED), Erectile Dysfunctions
A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction
This is a single arm dose escalation trial of a mucoadhesive intraurethral polymer suspension of alprostadil (ST-04) and will investigate the efficacy of 3 dose levels of ST-04 in adult males with a clinical diagnosis of Erectile…
- Conditions
- Erectile Dysfunction (ED), Erectile Dysfunctions, Erectile Function
- Trial name
- NCT07601646
- Testing
- ST-04
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Ryan Flannigan, MD
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction
Effect of Sildenafil on Quality of Sexual Life in Mild to Normally Sexually Functioning Males
In clinical practice it is quite common to have sexually active male patients with mild/normal erectile function that are not satisfied with their sexual function.
- Trial name
- NCT00313898
- Testing
- sildenafil (viagra)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus