Clinical trials: Epilepsy Sleep
Epilepsy, Insomnia
App-based Intervention for Treating Insomnia Among Patients With Epilepsy
Sleep can affect frequency and occurrence of interictal spikes and occurrence, timing, and threshold of seizure. Epilepsy can worsen sleep architecture and severity of sleep disorders. Thus, a vicious cycle is set.
- Trial name
- NCT03683381
- Testing
- Sleep Health, Patient education
- Where
- 4 sites in Iran
- Volunteers
- 320 people
- Sponsor
- Qazvin University Of Medical Sciences
Epilepsy
Transcranial Stimulation During Sleep to Improve Cognition in Epilepsy
Aim 1: Determine whether sleep enhances learning across a range of cognitive domains in healthy subjects. Aim 2: Determine whether low-frequency transcranial stimulation (TCS) delivered during slow wave sleep (SWS), compared to…
- Trial name
- NCT02268591
- Testing
- Transcranial Stimulator
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Lennox-Gastaut Syndrome
Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Lennox-Gastaut syndrome is a severe epileptic encephalopathy of childhood. In that syndrome, various type of seizure occur, mainly tonic seizures, atonic seizures and atypical absences. The tonic seizure occur mostly at night.
- Trial name
- NCT01370486
- Testing
- melatonin
- Where
- Switzerland
- Sponsor
- Institution de Lavigny
Reflexology, Epilepsy
Reflexology on Seizure Frequency, Fatigue, Stress and Sleep Quality in Epilepsy Patients
Epilepsy is among the diseases that cause loss of neurological abilities regardless of any trauma. Reflexology is one of the complementary therapies based on activating the body's self-healing power through special hand…
- Conditions
- Reflexology, Epilepsy, Fatigue, Stress
- Trial name
- NCT06120101
- Testing
- Reflexology Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Epilepsy, Electroencephalogram
The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in Children
This study aims to determine the safety and effectiveness of oral melatonin as natural inducer of sleep to acquire useful EEGs in South African children following its introduction as the main agent used in the Neurophysiology…
- Conditions
- Epilepsy, Electroencephalogram, Children, Sedation
- Trial name
- NCT02195661
- Testing
- Melatonin, Chloral Hydrate
- Where
- South Africa
- Volunteers
- 194 people
- Sponsor
- University of Cape Town
Focal Epilepsy
Sleep Architecture & Cognition in Focal Epilepsy
Focal Epilepsy (FE) patients and healthy controls will wear an actigraph at home for one week and a home sleep study device at home for one night.
- Trial name
- NCT05794295
- Testing
- Acoustic Stimulation (AS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Epilepsy
The Effect of Yoga on Sleep and Quality of Life in Epilepsy Patients
Determining the sleep quality and quality of life of epilepsy patients and offering solutions can be effective in their success both in their professional and social lives.
- Trial name
- Yoga (NCT04828876)
- Testing
- Yoga practice
- Volunteers
- 60 people
- Sponsor
- Zülfünaz ÖZER
Sleep Disordered Breathing, Apnea of Prematurity
The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study
Diagnostic investigations in paediatric respiratory and sleep medicine are often challenging due to patient size (due to prematurity), tolerability, and compliance with "gold standard equipment".
- Conditions
- Sleep Disordered Breathing, Apnea of Prematurity, Respiratory Rate, Sudden Unexpected Death in Epilepsy
- Trial name
- PARS (NCT06292299)
- Testing
- Pneumowave
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- NHS Greater Clyde and Glasgow
Epilepsy, Insomnia
A Computerized CBTi for Insomnia in Epilepsy
This is a pilot study. The Investigators propose a pilot randomized, parallel-group, controlled trial comparing the GoToSleep program (GTS) and controls on change in Insomnia Severity Index (ISI) from baseline to week 8 in adults…
- Trial name
- NCT03632889
- Testing
- GoToSleep Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Developmental Disability, Chronic Disease
QoL and Stress in Parents of Children With Developmental Disabilities and Chronic Disease
The aim of this cross-sectional study is to investigate the level of stress and quality of life in parents of children with developmental disabilities (Down syndrome, autism spectrum disorder, pervasive developmental disorder…
- Conditions
- Developmental Disability, Chronic Disease, Down Syndrome, Autism Spectrum Disorder
- Trial name
- NCT03602378
- Testing
- salivary cortisol, Holter Medilog AR12 Plus, Polar V800
- Where
- 2 sites in Croatia
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Epilepsy in Children
The Effect of Exercise and Music on Sleep, Quality of Life and Emotional State in Children With Epilepsy
This study was planned as a randomized controlled experimental study with a pretest-posttest design to determine the effect of parental supervision and video-guided progressive relaxation exercise (PRE) and music recital on…
- Trial name
- NCT06300814
- Testing
- Progressive relaxation exercise group, Music recital group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- TC Erciyes University
Sleep Apnea, Temporo-central Epilepsy
Sleep and Memory in Children
Sleep exerts a dual effect on learning: on the one hand, good sleep quality allows good daytime aptitudes leading to knowledge acquisition. On the other hand, sleep after learning is necessary for knowledge consolidation.
- Conditions
- Sleep Apnea, Temporo-central Epilepsy, Narcolepsy, High Intellectual Potential
- Trial name
- EnSOM (NCT02785328)
- Testing
- memory evaluation at V1 and V2 (with treatment), memory evaluation at V1 (without treatment), memory evaluation at V1 and V2 (without treatment)
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Epilepsy in Children, Epilepsy
Sleep, Music, And Research Trial 2.0
The goal of this clinical trial is to learn if a music-based intervention works to improve sleep and health in children with epilepsy and their parents.
- Trial name
- SMART-2 (NCT07696442)
- Testing
- Music-based intervention
- Where
- Taiwan
- Volunteers
- 144 people
- Sponsor
- National Taiwan University Hospital
Epilepsy
Aromatherapy and Music on Sleep and Children With Epilepsy
Purpose: This study aimed to compare the effects of aromatherapy and music listening with routine care on sleep parameters and cerebral oxygenation in children with epilepsy.
- Trial name
- NCT07827729
- Testing
- Aromatherapy, Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kafkas University
Refractory Epilepsy, SYNGAP1 Encephalopathy
Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes
This study is a pilot non-controlled clinical trial with adjunctive fenfluramine for the treatment of five different types of developmental and epileptic encephalopathies (DEEs) focused on epileptic and "non-epileptic outcomes"…
- Conditions
- Refractory Epilepsy, SYNGAP1 Encephalopathy, STXBP1 Encephalopathy With Epilepsy, Inv Dup(15) Encephalopathy
- Trial name
- FENDEEP (NCT05232630)
- Testing
- Fenfluramine
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Ruber Internacional
Epilepsy in Children
Getting SMART for Pediatric Epilepsy
The purpose of this study is to evaluate the effect of melatonin for improving sleep in pediatric epilepsy.
- Trial name
- NCT05439876
- Testing
- Melatonin
- Where
- Taiwan
- Volunteers
- 147 people
- Sponsor
- National Taiwan University Hospital
Epilepsy
Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG
This study will evaluate how the state of being completely deprived of sleep has an effect on recordings of magnetoencephalography (MEG) and electroencephalography (EEG), in relation to how alert someone is and how sleepy someone…
- Trial name
- NCT00071370
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Electrical Status Epilepticus in Sleep
Study of Patients with Electrical Status Epilepticus in Sleep
Our aims are: 1. To understand the diagnostic practices, treatment and long term management and outcomes for patients diagnosed with ESES locally. 2.
- Trial name
- SPESES (NCT06792396)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Epilepsy
Management Strategies For Electrical Status Epilepticus During Sleep
Electrical status epilepticus during slow wave sleep is a condition in which the epileptic patient starts to develop neurocognitive deterioration, any type of seizures and continuous electrical activity in the EEG during non…
- Trial name
- NCT03251820
- Testing
- corticosteroid
- Volunteers
- 50 people
- Sponsor
- Randa Abdelbadie Abdelaleem