Clinical trials: Endotracheal Intubation
Adverse Reaction to Drug, Neonatal Disorder
Exploratory Propofol Dose Finding Study In Neonates
The aim of the study is to explore the optimal propofol dose in neonates receiving a single intravenous propofol bolus for endotracheal intubation during (semi-)elective INSURE (intubation-surfactant-extubation) procedure…
- Trial name
- NEOPROP (NCT01621373)
- Testing
- propofol administration
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Respiratory Failure, Intubation Complication
Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death.
- Trial name
- PrePARE (NCT03026777)
- Testing
- intravenous crystalloid fluid, 500 mL
- Where
- 7 sites in United States
- Volunteers
- 337 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Endotracheal Intubation
Intubating Conditions of Neuromuscular Blockade
The purpose of this research is to learn about the difference in the endotracheal intubation condition (ease of using a device to view vocal cords, position of vocal cords, and patient's reaction to endotracheal tube insertion)…
- Trial name
- NCT05620108
- Testing
- Endotracheal Intubation at TOFC=1, Endotracheal Intubation 2 minutes after rocuronium administration
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Respiratory Failure
Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study
Respiratory failure requiring endotracheal intubation occurs in as many as 40% of critically ill patients. Procedural complications including failed attempts at intubation, esophageal intubation, arterial oxygen desaturation…
- Trial name
- FELLOW (NCT02051816)
- Testing
- Video Laryngoscopy, Apneic Oxygenation, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vanderbilt University
Respiratory Distress Syndrome, Newborn
Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation
In this study, newborn babies with respiratory distress syndrome (RDS), receiving oxygen via nasal CPAP, and needing surfactant treatment will be randomized to standard delivery of surfactant via and endotracheal tube…
- Trial name
- NCT01042600
- Testing
- Endotracheal tube insertion, Laryngeal mask airway insertion
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Albany Medical College
Larynx
Examining the Ease of Intubation Using the Parker Flex-Tip® or a Standard Endotracheal Tube
The purpose of the study is to determine if there are differences related to ease of intubation reported by clinicians who use the Parker Flex-Tip® endotracheal tubes(ETT)compared to the standard Mallinckrodt® (ETT).
- Trial name
- ETT (NCT01263873)
- Testing
- Mallinckrodt (ETT), Parker Flex-Tip (ETT)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Acute Respiratory Failure
DirEct Versus VIdeo LaryngosCopE Trial
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- DEVICE (NCT05239195)
- Testing
- Video Laryngoscope, Direct Laryngoscope
- Where
- 12 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Vanderbilt University Medical Center
Ventilator-acquired Pneumonia
Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia
Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia.
- Trial name
- PreVent2 (NCT03705286)
- Testing
- EVAC-PU-ETT, PVC-ETT
- Where
- United States
- Volunteers
- 1,074 people
- Sponsor
- Yale University
Inguinal Hernia, Inguinal Hernia, Indirect
Laryngeal Mask Airway in Laparoscopic Hernia Repair
This prospective randomized study will evaluate the effectiveness of laryngeal mask airway (LMA) versus endotracheal intubation (ETT) for patients undergoing laparoscopic inguinal hernia at CMH.
- Conditions
- Inguinal Hernia, Inguinal Hernia, Indirect, Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
- Trial name
- NCT06023394
- Testing
- Laryngeal Mask Airway, Endotracheal Tube Device
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Mercy Hospital Kansas City
Airway Management, Intubation, Intratracheal
Soiled Airway Tracheal Intubation and the Effectiveness of Decontamination by Paramedics
In more than one-in-five cases of out-of-hospital cardiac arrest, airways are blocked by vomit and blood. Sometimes, paramedics cannot clear the airway using methods they have been taught.
- Conditions
- Airway Management, Intubation, Intratracheal, Laryngoscopy, Vomiting
- Trial name
- SATIATED (NCT03599687)
- Testing
- Training in SALAD technique
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- Yorkshire Ambulance Service NHS Trust
Cardiac Arrest
Pragmatic Airway Resuscitation Trial
The primary objective of the trial is to determine if 72-hour survival after out-of-hospital cardiac arrest (OHCA) is improved with initial endotracheal intubation (ETI) over initial laryngeal tube (LT) airway management…
- Trial name
- PART (NCT02419573)
- Testing
- Endotracheal Intubation, Laryngeal Tube (King)
- Where
- 6 sites in United States
- Volunteers
- 3,004 people
- Sponsor
- University of Alabama at Birmingham
Tracheal Intubation
Randomised Controlled Trial of Intubation With the McGrath Series 5 Video Laryngoscope vs the Macintosh Laryngoscope
The simplicity of use and intuitive function of the McGrath video-laryngoscope suggests it may have a bigger role than as a back-up to conventional direct laryngoscopy and could possibly be the first-line laryngoscope for…
- Trial name
- NCT00633867
- Testing
- McGrath, Tracheal intubation using Macintosh Laryngoscope
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- NHS Grampian
Endotracheal Intubation, Individualized Depth of Endotracheal Intubation
Determining the Depth of Endotracheal Tube Insertion
1. Airway length from the medial incisor to carina is divided into four segments ; the length from medial incisor to mouth angle, mouth angle to epiglottis, epiglottis to vocal cords and vocal cords to carina. 2.
- Trial name
- NCT02158247
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- The Catholic University of Korea
Endotracheal Intubation
Comparison Between Etview Tracheoscopic Ventilation Tube - TVT to Standard Endotracheal Intubation
Airway management is one of the most important tasks facing the physician, especially the anesthesiologist. Fast and correct performance of endotracheal intubations done as normal routine in the operating room, but can save life…
- Trial name
- NCT01279564
- Testing
- ETview TVT endotracheal tube, Endotracheal tube
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Rambam Health Care Campus
Difficult Intubation
Comparison of Endotracheal Intubation Over the Aintree Via the I-gel and Laryngeal Mask Airway Supreme
The investigators plan to conduct a randomized trial comparing the efficacy of intubating the tracheal using an Aintree intubation catheter through either the LMA-S or I-gel supraglottic devices
- Trial name
- NCT02476565
- Testing
- LMA-Supreme supraglottic device, I-gel supraglottic device
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Vanderbilt University
Anesthesia Intubation Complication
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
The purpose of this study is to determine the amount of propofol required to achieve 50% of patients obtaining a perfect ("excellent") intubation score of 5 on the Steyn modification of the Helbo-Hansen Intubation Score, when…
- Trial name
- NCT01150838
- Testing
- propofol
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia
Child
Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children
Children lose heat under general anaesthesia, thus temperature is routinely monitored during anaesthesia for all but the shortest cases, and active warming can be used to prevent hypothermia and its resulting complications.
- Trial name
- NCT02201628
- Testing
- Nasopharyngeal and oesophageal temperature probes
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Failed or Difficult Intubation, Sequela, Intubation;Difficult
Tracheal Intubation Coaching in NICUs
The purpose of the study is to determine the efficacy of video coaching training for neonatology attending providers on tracheal intubation procedural outcomes in neonatal ICUs.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation;Difficult, Intubation Complication
- Trial name
- NCT03194503
- Testing
- VL Coaching training using C-MAC video laryngoscope
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,512 people
- Sponsor
- Children's Hospital of Philadelphia
Ventilator Associated Pneumonia, Critically Ill
Efficacy Study on Silver-coated ETT Cleaned With a Novel Device
The purpose of this study is to test the efficacy of a novel cleaning device in keeping silver-coated endotracheal tubes free from bacterial colonization.
- Trial name
- NCT02120001
- Testing
- ETT cleaning maneuver
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital