Clinical trials: Emotional Dysfunction
Mental Health Disorder, Mental Health Impairment
Youth FORWARD Phase 1 YRI and EPP Study
Objectives: The objectives of this research proposal are to study the delivery of an evidence-based mental health intervention in the alternate setting of youth employment programs tied to regional economic development and to…
- Conditions
- Mental Health Disorder, Mental Health Impairment, Psychosocial Impairment, Emotional Dysfunction
- Trial name
- NCT03603613
- Testing
- YRI, EPP
- Where
- Sierra Leone
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston College
Chronic Urogenital Pain
Life-Stress Interview for Women With Chronic Urogenital Pain Conditions
The goal of this study is to test the efficacy, feasibility, and acceptability of providing an experiential assessment interview that targets health, and emotional and stressful experiences in a tertiary care setting specializing…
- Trial name
- NCT02286115
- Testing
- Life-Stress Interview
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Corewell Health East
Multiple Sclerosis (MS) - Relapsing-remitting, Anxiety
Psychological Interventions for Multiple Sclerosis: Effects on Anxiety, Depression, and Cognition.
This study evaluated the efficacy of two structured psychological interventions in individuals with relapsing-remitting multiple sclerosis (RRMS).
- Conditions
- Multiple Sclerosis (MS) - Relapsing-remitting, Anxiety, Depression, Cognitive Impairment
- Trial name
- MS-PSY (NCT07273604)
- Testing
- Cognitive Behavioral Therapy (CBT), Psychophysiological Regulation Therapy (PRT)
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Moisés Bermúdez Hernández
Psychological Stress, Mental Fatigue
Psychophysiological Effects of Green Exercise in Outdoor Green vs. Indoor Control
Core Purpose: Researchers want to learn if walking in an outdoor green environment helps people recover from mental tiredness and stress better than walking indoors.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- GREEN-OI (NCT07379164)
- Testing
- Outdoor Green Group, Indoor Control Group
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Focus Groups in Ethnically and Racially Diverse Families
Focus groups to identify treatment needs and barriers to participation in the planned multinutrient study among racially and ethnically diverse (Black and Hispanic) communities.
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- NCT05930886
- Testing
- Focus Group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
COVID-19 Pandemic, Depression, Anxiety
Older Adults' Perceptions of the Impact COVID-19 Pandemic
This multicentre study will be conduct in several Portuguese institutions, which provide care and supporting services for older adults, with aim to assess the impact of COVID-19 pandemic on the cognitive, emotional and social…
- Conditions
- COVID-19 Pandemic, Depression, Anxiety, Cognitive Impairment, Quality of Life
- Trial name
- NCT05379426
- Testing
- Impact COVID-19 pandemic
- Where
- 58 sites in Portugal
- Volunteers
- 880 people
- Sponsor
- Rsocialform - Geriatria, Lda
COVID-19, Cognitive Dysfunction
Long-Covid: Treatment of Cognitive Difficulties
The purpose of the study is to explore the potential effectiveness of two common low-dose interventions, one targeting cognitive difficulties and the other targeting affective difficulties on quality of life and cognition in…
- Trial name
- COV-COG (NCT05167266)
- Testing
- Psychoeducation
- Where
- 5 sites in Belgium
- Volunteers
- 130 people
- Sponsor
- University of Liege
Epilepsy, Quality of Life
Idiopathic Generalized Epilepsy Cognitive and Emotional Profile
The primary goal of the study is to explore the neurocognitive, emotional-behavioral functioning, and quality of life of adolescents with IGE, identifying key factors that affect their overall well-being.
- Conditions
- Epilepsy, Quality of Life, Neuropathology, Emotional Problem
- Trial name
- NCT06782074
- Testing
- emotional and neuropsychological assessment
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Emotional Dysfunction
Does Heart Rate Variance (HRV) Biofeedback Help Regulate Emotions and Improve Mindfulness in Mentally Unwell Offenders?
14 participants residing in a forensic psychiatric hospital completed 15 Heart Rate Variance (HRV) biofeedback sessions. They completed 4 psychometric questionnaires, pre, during and post biofeedback training.
- Trial name
- NCT04273113
- Testing
- Difficulties in Emotional Regulation Scale, Five Facet Mindfulness Questionnaire, Becks Depression and Becks Anxiety, HRV Biofeedback (Healing Rhythms)
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Birmingham
Cushing Syndrome
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome
This is a prospective, multi-center, case-control study where neurocognitive function will be evaluated in 36 patients with Cushing syndrome (CS) and 36 controls matched for age, gender and education.
- Trial name
- NCT03211624
- Where
- 3 sites in Netherlands, Spain and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Rectal Cancer, Quality of Life
The OPERa Study: Evaluating QoL After Rectal Cancer Surgery
Advances in rectal cancer management have significantly reduced morbidity and mortality. The most commonly performed operation for rectal cancer is restorative proctectomy (RP), leaving up to 70% with long-term bowel dysfunction…
- Conditions
- Rectal Cancer, Quality of Life, Bowel Dysfunction, Sexual Dysfunction
- Trial name
- NCT04893876
- Volunteers
- 1,200 people
- Sponsor
- Jewish General Hospital
Stroke, Fatigue
Emotional and Cognitive Determinants of Post-stroke Fatigue
Fatigue is a prevalent, prolonged and partly disabling symptom following cerebral stroke. The health services has little knowledge of fatigue, both in terms of what characterizes those affected, and with regard to how fatigue can…
- Conditions
- Stroke, Fatigue, Post-Stroke Fatigue, Neuropsychology
- Trial name
- NCT03639259
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- University Hospital of North Norway
Social Isolation in Older Adults, Poverty
Multimodal Training With Immersive Virtual Reality to Improve the Cognitive Health and Emotional Well-being of Older Women Living Alone
This study aims to evaluate the effectiveness of an immersive virtual reality-based multimodal intervention (VirtualDONA) to improve cognitive health and emotional well-being in older women living alone and at risk of poverty.
- Trial name
- VirtualDONA (NCT06956794)
- Testing
- VirtualDONA Multimodal Program
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari de Terrassa
Emotional Dysfunction, Early Life Stress
Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity
This study will examine the effect of a real-time functional magnetic resonance imaging (fMRI) dyadic neurofeedback protocol with mothers and their adolescent daughters.
- Trial name
- NCT04964726
- Testing
- Real-time fMRI dyadic neurofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Cancer, Breast
Unified Barlow Protocol (UP) in Cancer Survivors for Cognitive Impairments
Background: Cognitive impairment appears frequently in cancer survivors, negatively affecting the quality of life and emotional well-being of patients.
- Trial name
- NCT05289258
- Testing
- Neuropsychological treatment, Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (PU)., Waitlist group
- Where
- 2 sites in Spain
- Volunteers
- 123 people
- Sponsor
- Universidad de Córdoba
Severe Eosinophilic Asthma, Psychological Distress
Severe Asthma, MepolizumaB and Affect: SAMBA Study
This is a real-life pragmatic non-randomised study to explore the impact of mepolizumab on the emotional and affective outcomes of patients with severe eosinophilic asthma and their partners.
- Conditions
- Severe Eosinophilic Asthma, Psychological Distress, Anxiety, Depression
- Trial name
- SAMBA (NCT04680611)
- Testing
- no study intervention. Patients receive standard clinical care
- Where
- 6 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Alzheimer Disease, Stroke
Assessment of Social-emotional Functioning in Neurological Diseases
Empathy, defined as the ability to understand others emotions, is a fundamental concept in social interactions. It is a psychological phenomenon involving various separable components : (i) the ability to feel and imagine the…
- Conditions
- Alzheimer Disease, Stroke, Parkinson's Disease, Lewy Body Dementia
- Trial name
- Emotion (NCT01339130)
- Testing
- Computerized tests and Electrophysiological measurements
- Where
- France
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Kidney Failure, Chronic, Cognitive Dysfunction
Emotion and Cognitive Function and Brain Imaging Change in HD Patients
1. Observe the influence of entering hemodialysis treatment on the emotional and cognitive functions of ESRD patients. 2. Observe the influence of entering hemodialysis treatment on the brain structure imaging of ESRD patients.
- Conditions
- Kidney Failure, Chronic, Cognitive Dysfunction, Magnetic Resonance Imaging
- Trial name
- NCT05137470
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Mild Cognitive Impairment, Depressive Symptoms
Homebound Elderly People Psychotherapeutic Intervention
This study aims to develop, implement, and assess the feasibility, acceptability, and preliminary efficacy of a 10-week structured and individualized cognitive-emotional intervention program for homebound older adults with Mild…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT04967378)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Coimbra
Alzheimer Disease, Mild Cognitive Impairment
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Recent findings suggest that sleep disruption may contribute to the generation and maintenance of neuropsychiatric symptoms including anxiety, depression, agitation, irritation, and apathy while treating sleep disruption reduces…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
- Trial name
- NCT04100057
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Desensitization Therapy for insomnia (DT-I)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University