Clinical trials: Edentulous Jaws, open to volunteers
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Edentulous Jaw
Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System
Group I (control) Edentulous mandible receiving all on four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.
- Trial name
- NCT05924386
- Testing
- patients reciveing all on 4 fixed mandibular prosthesis usimg conventionally screw retained multiunit abutments, all on 4 fixed mandibular prosthesis using OTbridge attachment system
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Jaw, Edentulous, Partially, Missing Teeth
Two-unit Cantilever Implant Prostheses Made of Monolithic Zirconia or PFM
The aim of is to compare the survival rate and technical outcomes of cantilever implant-supported fixed denture prosthetics (cFDPs) made either out of monolithic zirconia bonded to a titanium base in a digital workflow, or…
- Trial name
- Cantilever (NCT04713800)
- Testing
- Monolithic zirconia screw retained implant-supported cantilever reconstruction supported by titanium base abutments, in a full digital workflow (ZR-TiB), porcelain fused-to metal screw retained implant-supported cantilever reconstruction supported by a gold-abutment, in a conventional workflow (PFM-GA)
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Partially Edentulous Jaw, Tooth Loss
Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System Falcon
The Falcon Study is a prospective, multicenter, multinational clinical investigation evaluating the Straumann® Dynamic Navigation System (Falcon) for dental implant placement.
- Conditions
- Partially Edentulous Jaw, Tooth Loss, Dental Implant
- Trial name
- Falcon (NCT07518615)
- Testing
- Post-operative Cone Beam Computed Tomography (CBCT), Straumann Falcon Dynamic Navigation System, Dental Implants
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 75 people
- Sponsor
- Institut Straumann AG
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Esthetic, Clinical and Radiographic Outcomes of Immediate and Delayed Implant Placement
The aim of this prospective cohort study is to compare the esthetic, clinical and patient-centered outcomes following immediate and delayed implant placement protocols.
- Trial name
- NCT02814149
- Testing
- Type 1 implant placement, Type 3 implant placement
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Evaluation of Bone Changes Around Implants in Patients Treated With All on Four
The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, All on Four Technique, Dental Implant
- Trial name
- NCT06723678
- Testing
- Two distally inclined 45-degree angle posterior implants, Two distally inclined 30-degree angle posterior implants
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Edentulous Mouth, Edentulous Jaw
Clinical Outcomes of 3D Printed and Milled Complete Dentures
This is a two-armed, single-center clinical study evaluating performance, efficacy and safety of three dimensional (3D) printed complete dentures and milled complete dentures during a 5-year follow-up period.
- Trial name
- NCT07586774
- Testing
- Lucitone Digital Print, Lucitone Digital Fit
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Edentulous Jaw, Tooth Loss
Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites
The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time.
- Conditions
- Edentulous Jaw, Tooth Loss, Toothless Mouth
- Trial name
- NCT07177521
- Testing
- Insertion of implants in post-extraction tooth
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Dental Implants, Edentulous Jaw
Passive Fit of Implant-Supported Frameworks: Digital vs Conventional Impressions
This randomized crossover clinical trial compares the passivity of fit of complete-arch mandibular implant-supported frameworks fabricated using three impression techniques: a non-calibrated splinted digital scan body system…
- Conditions
- Dental Implants, Edentulous Jaw, Passive Fit
- Trial name
- NCT07778199
- Testing
- IO-Connect Digital Impression, Reverse Scan Body Digital Impression, Conventional Splinted Impression
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Mansoura University
Partial Edentulism
Digital and Conventional Clasp-retained Partial Dentures (DIGICLASP)
This single-center prospective observational cohort study evaluates two fabrication workflows already in routine clinical use for clasp-retained removable partial dentures (RPDs): a digital workflow (Group 1) and a conventional…
- Trial name
- DIGICLASP (NCT07903662)
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Edentulous Maxilla, Maxillary Bone Loss
NobelZygoma TiUltra Implant System Study
The goal of this prospective study is to assess short term (12-months) clinical outcomes of NobelZygoma TiUltra implants and Multi-unit Abutment Xeal in the rehabilitation of participants with severely atrophic maxilla treated…
- Conditions
- Edentulous Maxilla, Maxillary Bone Loss, Atrophic Maxilla
- Trial name
- NCT07258940
- Testing
- NobelZygoma™ 0° CC TiUltra™implant ; NobelZygoma™ 45° Ext Hex TiUltra™ implant, Multi-Unit Abutment Xeal Zygoma Ext Hex RP; 17° Multi-Unit Abutment Xeal Zygoma Ext Hex RP; 45° Multi.Unit Abutment Xeal Zygoma CC RP; 60° Multi-Unit Abutment Xeal Zygoma CC RP
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 85 people
- Sponsor
- Nobel Biocare
Chewing Efficiency in Completely Edentulous Patients Rehabilitated With Implant-Supported Full-Arch Prostheses
Dynamic vs. Static Jaw Relations in Implant-Supported Prostheses: Chewing Efficiency
This study aims to compare the chewing efficiency of implant-supported full-arch prostheses fabricated using two different jaw relation registration techniques: conventional static jaw relation registration and dynamic jaw…
- Trial name
- NCT07890389
- Testing
- Conventional Static Jaw Relation Registration, Dynamic Digital Jaw Tracking Registration
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Atrophic Edentulous Maxilla, Zygomatic Implants
Assessment of Soft Tissue Thickness Over Zygomatic Implants in Atrophied Maxilla Covered With Buccal Fat Pad vs. Palatal Pedicle Flap
Background and Rationale The rehabilitation of the severely atrophied maxilla utilizing zygomatic implants is a highly predictable and effective treatment modality.
- Conditions
- Atrophic Edentulous Maxilla, Zygomatic Implants, Dental Implant, Soft Tissue Augmentation at Dental Implants
- Trial name
- NCT07574606
- Testing
- Palatal pedicle over zygomatic implant, covering zygomatic implants using buccal fat pad
- Where
- Egypt
- Volunteers
- 4 people
- Sponsor
- Future University in Egypt
Edentulous Alveolar Ridge, Edentulous Alveolar Ridge Atrophy
Freeze-dried Bone Allograft vs Autologous Bone Blocks in the Lateral Augmentation of the Jaws
After tooth loss, the alveolar ridge undergoes various modeling and remodeling processes, resulting in overall bone resorption. In case of extensive alveolar atrophy, bone volume must be restored before or during implant…
- Trial name
- NCT07104370
- Testing
- Bone augmentation using an autologous bone block, Bone augmentation using freeze-dried allograft block, preoperative cone beam computed tomography (CBCT)
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Semmelweis University
Jaw, Edentulous, Partially, Bone Resorption
Clinical and Radiographic Evaluation of UV-Treated Dental Implants With or Without Melatonin in the Upper Posterior Jaw
The purpose of this study is to evaluate and compare the clinical and radiographic outcomes of using photofunctionalized (UV-treated) dental implants with or without the application of melatonin hormone in the posterior maxilla…
- Conditions
- Jaw, Edentulous, Partially, Bone Resorption, Dental Implant Failure
- Trial name
- UV-MEL-IMPLANT (NCT07853976)
- Testing
- UV-Photofunctionalized Dental Implant, Conventional Dental Implant
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulous Jaw
Trueness of Intra-Oral Scanners Compared to an Extra-Oral Scanner for Scanning of Mandibular Edentulous Impressions
the relative accuracy of different intraoral scanner types specifically for capturing the complex morphology of edentulous arches, including peripheral borders and mobile tissues, remains an area of investigation, with…
- Trial name
- NCT07740798
- Testing
- Digital impression of the mandibular edentulous arch
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Edentulous Jaw
Facial Prediction Technology for Edentulous Patients
According to data from the World Health Organization, approximately 160 million people worldwide are edentulous. The incidence increases with age, and the proportion of edentulous patients is higher in the population aged 60 and…
- Trial name
- NCT06080633
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Jaw, Edentulous, Partially, Diabetes
Maxillary Sinus Floor Augmentation in Diabetic Patients
Placement of implants in diabetic patients is associated with higher risk of implant failure and peri-implant marginal bone loss due to an increased susceptibility to infections, impaired wound healing and associated…
- Trial name
- NCT04543630
- Testing
- Sinus floor augmentation
- Where
- 3 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Copenhagen
Dental Implant, Dental Implant-Abutment Design
RCT Comparing KS Versus TS for Ovedenture
To evaluate the clinical and radiographic outcomes of KS implants used to rehabilitate edentulous mandible with dental-retained overdentures, and to compare it with same treatment on TS implants
- Conditions
- Dental Implant, Dental Implant-Abutment Design, Edentulous Jaw
- Trial name
- NCT06276712
- Testing
- Implant placement with 3.5 mm diameter KS implants., Implant placement with 3.5 mm diameter TS implants.
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari