Clinical trials: Early Intervention, active
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Sepsis, Deterioration, Clinical
Hospital-Onset Sepsis Systematic Detection and Structured Interventions
Sepsis is a life-threatening reaction to an infection. It can begin while a person is already in the hospital for some other reason. Sepsis that starts in the hospital is often recognized late, and treatment can be delayed.
- Conditions
- Sepsis, Deterioration, Clinical, Critical Illness, Early Warning Score
- Trial name
- CATCH SEPSIS (NCT07804251)
- Testing
- Algorithm-triggered sepsis alert with structured critical care team activation
- Where
- United States
- Volunteers
- 3,700 people
- Sponsor
- Patricks Lyons
ATTR-CM
Implementation of Standardized Early Identification and Diagnosis for Transthyretin Amyloidosis (ATTR) in High-Risk Populations
This multicenter, prospective, single-arm, interventional study will enroll about 4,000 adult patients at high risk of ATTR amyloidosis from around 50 sites in China.
- Trial name
- NCT07338942
- Testing
- implementation of standard early identification and diagnosis of ATTR
- Where
- 48 sites in China
- Volunteers
- 4,000 people
- Sponsor
- AstraZeneca
Child Development, Parenting
Impact of the Korea Early Childhood Home-visiting Intervention
Maternal and early childhood home visits have been proposed as an effective strategy to improve the health and development of disadvantaged children.
- Conditions
- Child Development, Parenting, Infant Development, Pregnancy Related
- Trial name
- KECHI (NCT04749888)
- Testing
- Targeted nurse-led home visiting
- Where
- 2 sites in South Korea
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Autism Spectrum Disorder, Emotional Regulation
Effectiveness of Robot-Assisted Intervention and Sensory Integration Therapy in Enhancing Social-Emotional Skills in Children With Autism
This study is designed to evaluate and compare the impact of robot-assisted intervention using a smart robot (Kebbi Air) and traditional sensory integration therapy on improving social-emotional skills in children diagnosed with…
- Conditions
- Autism Spectrum Disorder, Emotional Regulation, Sensory Integration Dysfunction
- Trial name
- NCT06757673
- Testing
- Robot-Assisted Therapy using Kebbi Air, Sensory Integration Therapy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Smoking Cessation, Early-Stage Cancer
Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of a Multi-Theory Model (MTM)-based AI agent intervention for smoking cessation in early-stage cancer patients (clinical stage cTNM 0~II) who currently smoke.
- Conditions
- Smoking Cessation, Early-Stage Cancer, AI Agent
- Trial name
- NCT07827066
- Testing
- MTM-Based AI Agent for smoking cessation, Counseling
- Volunteers
- 156 people
- Sponsor
- Sun Yat-sen University
Acute Kidney Injury
An Early Real-Time Electronic Health Record Risk Algorithm for the Prevention and Treatment of Acute Kidney Injury
This is a single center randomized trial that seeks to determine if the use of an automated real-time electronic medical record Acute Kidney Injury (AKI) risk score can improve patient outcomes through the use of an early…
- Trial name
- ESTOP-AKI (NCT03590028)
- Testing
- Early Nephrology Consult (ENC), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Chicago
Peer Bullying Intervention, Vodcast
Early Detection and Kinetics of Sepsis-Induced Coagulopathy in Severe Burn Patients
The purpose of this study is to evaluate the impact of an avatar-supported, teacher-student interactive, vodcast-based peer bullying prevention program-developed for adolescents-on students' ability to identify peer bullying…
- Conditions
- Peer Bullying Intervention, Vodcast, Students
- Trial name
- SIC-BURN-JAAM2 (NCT07905807)
- Testing
- Vodcast-Based Peer Bullying Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dual Diagnosis, Alcohol Use Disorder
The 15-Mental Project: Implementation and Evaluation of the 15-Mental in a Mental Health Hospital Setting
The present project will implement and evaluate the effectiveness of a novel, but simple model for addressing and treating alcohol problems among patients admitted to outpatient treatment at mental health hospitals, called the…
- Conditions
- Dual Diagnosis, Alcohol Use Disorder, Hazardous Alcohol Use, Screening and Brief Intervention
- Trial name
- NCT07728968
- Testing
- 15-Mental.
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Sepsis
Development of Context-Adapted Quality Indicators for Early Sepsis Care in Sub-Saharan Africa - A Modified Delphi Consensus Procedure
The research project is an anonymous, prospective, non-interventional consensus study in the form of a modified Delphi method, consisting of three online surveys and structured feedback meetings without recording.
- Trial name
- NCT07711535
- Where
- Ghana
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Prehabilitation
Multimodal Prehabilitation Program That Combines Physical Exercise, Psychological Intervention and Nutritional Support to Improve the Response to Neoadjuvant Chemoterhapy in Early Breast Cancer Patients
The aim of this clinical trial is to evaluate whether following a multimodal prehabilitation program including physical exercise, nutritional support and psychological intervention during neoadjuvant chemotherapy in breast cancer…
- Trial name
- DIANA (NCT07107594)
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Hospital Clinic of Barcelona
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative Treatment
This trial studies the effect of a geriatric care survivorship intervention in improving the overall health of older adults who have completed curative treatment for stage I-III breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT05928325
- Testing
- Comprehensive Geriatric Assessment, Health Education, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Dietary Intakes, Physical Activity
Implementing Modified Practices to Leverage Evidence for Movement, Engagement, and Nutrition Topics in Early Childcare and Education
The goal of this cluster-randomized, controlled trial is to learn if a professional development program for childcare educators, called the Boston Healthy Child Care Initiative, can help improve the nutritional quality of…
- Conditions
- Dietary Intakes, Physical Activity, Child Care, Early Education
- Trial name
- IMPLEMENT (NCT07874295)
- Testing
- Boston Healthy Child Care Initiative
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Respiratory Failure, Communication Disorders
Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life
This study evaluates the impact of early tracheostomy speaking valve intervention on communication ability, depression levels, and quality of life in ventilator-dependent patients during the weaning phase.
- Conditions
- Respiratory Failure, Communication Disorders, Depression, Quality of Life
- Trial name
- NCT07005596
- Testing
- Passy-Muir Speaking Valve, Standard Non-Verbal Communication Methods
- Volunteers
- 70 people
- Sponsor
- Far Eastern Memorial Hospital
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gross Motor Development Delay
Video-based Assessment of Preschool Children's Gross Motor Development
Artificial intelligence (AI) is currently one of the global focal points for industrial development, with its applications in healthcare steadily increasing, such as in disease prediction, image diagnosis, and drug development.
- Trial name
- NCT07054437
- Testing
- Gross Motor Development Screening Tool
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Early Intervention in Cognitive Aging
Nutritional intervention in overweight middle aged individuals with subjective memory complaints.
- Trial name
- NCT02751866
- Testing
- Berry fruit powder OR nutritional ketosis
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Cincinnati
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Alzheimer Disease, Dementia
Music for Pain and Dementia
This study aims to provide mechanistic insights into how group drumming as a music-based intervention (MBI) affects pain responses and nociceptive function in individuals with Alzheimer's Disease (AD), mild dementia or mild…
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Peer-bonded Caregiver
- Trial name
- Music4Pain (NCT07602283)
- Testing
- Drumming session, Music-listening session
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University