Clinical trials: ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
Enlarged Lymph Nodes (Excluding Infective)
Evaluation of 19-gauge vs 21-gauge EBUS TBNA in Assessing Thoracic Lymphadenopathy
This study compares the yield of 19-gauge needles vs 21-gauge needles during EBUS TBNA procedures.
- Trial name
- NCT03657849
- Testing
- EBUS TBNA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- HealthPartners Institute
Mediastinal Lymph Node Enlargement, Sarcoidosis
Bronchoscopic Sampling Techniques in Sarcoidosis
The development of endobronchial ultrasound (EBUS) and EBUS-guided transbronchial needle aspiration (EBUS-TBNA) has improved the safety and diagnostic accuracy of the mediastinal lymph node (MLN) sampling.
- Conditions
- Mediastinal Lymph Node Enlargement, Sarcoidosis, Tuberculosis, Lymphomas
- Trial name
- NCT01836822
- Testing
- EBUS guided transbronchial forceps biopsy (EBUS-TBFB), EBUS guided transbronchial needle aspiration (EBUS-TBNA), large bore (19G) histologic needle biopsy of the mediastinal lymph nodes
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Lung Cancer
The Role of Sedation Technique in EBUS-TBNA
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy.
- Trial name
- NCT02245295
- Testing
- Moderate Sedation for EBUS/TBNA, General anesthesia for EBUS/TBNA
- Where
- Switzerland
- Volunteers
- 232 people
- Sponsor
- University of Zurich
Sarcoidosis
Trial for the Diagnosis of Sarcoidosis
This randomized study investigates two different diagnostic strategies for patients with suspected pulmonary sarcoidosis stage I/II.
- Trial name
- GRANULOMA (NCT00872612)
- Testing
- EUS-FNA/EBUS-TBNA + BAL, EBB + TBLB + BAL
- Where
- 15 sites in Belgium, Denmark and 4 more
- Volunteers
- 304 people
- Sponsor
- Leiden University Medical Center
Tuberculosis
Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes
This is an observational prospective study. Role of EBUS-TBNA (endobronchial ultrasound transbronchial needle aspiration) is evaluated to diagnose tuberculosis in mediastinal and/or hilar lymph nodes.
- Trial name
- NCT01350674
- Testing
- EBUS-TBNA
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Mediastinal Lymphadenopathies, Mediastinal Masses
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation
The purpose of the study is to determine if there are any differences in yield or safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) (a type of bronchoscopy with biopsy) performed under general…
- Conditions
- Mediastinal Lymphadenopathies, Mediastinal Masses, Hilar Lymphadenopathies
- Trial name
- EBUS-GA-MS (NCT01430962)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Baylor College of Medicine
Lung Cancer
Safety Evaluation of Dexmedetomidine for EBUS-TBNA
Lung cancer is the second most commonly diagnosed primary neoplasia in Canada accounting for 22 865 new cases in 2007. Recent randomized trials have shown a significantly better diagnostic yield and fewer unnecessary…
- Trial name
- EBUSed (NCT01381627)
- Testing
- Remifentanil, Dexmedetomidine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Lung Diseases
Nasal Versus Buccal Oxygen Administration for Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
The purpose of this study is to compare to nasal and buccal oxygen administration in patients undergoing Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration .
- Trial name
- NCT04686656
- Testing
- nasal oxygen, buccal oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Mediastinal and Hilar Lymphadenopathy
Study of Procedural Efficiency in EBUS With Dual Versus Single NEEDLEs: Evaluating the Value of a Second Needle in EBUS as it Pertains to Economic and Environmental Impact
Currently, the EBUS bronchoscopy procedure uses either one or two needles to perform the biopsy of the lymph node based on physician preference.
- Trial name
- SPEED NEEDLE (NCT07218042)
- Testing
- We randomized patients to the two arms above; there was no specific intervention performed other than randomizing patients to one or two needles.
- Where
- 3 sites in United States
- Volunteers
- 126 people
- Sponsor
- Christopher Kapp
Mediastinal Lymphadenopathy, Hilar Lymphadenopathy
Diagnostic Yield & Specimen Adequacy of Flex 19 G vs 22 G EBUS Needle - A Randomized Controlled Trial
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the minimally invasive diagnostic modality for the evaluation of mediastinal and hilar lymph nodes (LNs).
- Trial name
- EBUS-TBNA (NCT05535439)
- Testing
- EBUS-TBNA using 22 G EBUS-FNB Device OR 19 G EBUS-FNA needle
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Sarcoidosis
A Trial to Compare Two Methods of Obtaining Tissue for Diagnosis of Sarcoidosis Namely the Conventional Method or the Ultrasound Guided Method
This trial compares the yield of cTBNA (conventional Transbronchial Needle Aspiration) versus the EBUS-TBNA (Endobronchial Ultrasound guided TBNA) for obtaining cytology when they are combined with endobronchial biopsy and…
- Trial name
- NCT02472808
- Testing
- cTBNA without ROSE, cTBNA with ROSE, EBUS-TBNA without ROSE
- Where
- India
- Volunteers
- 80 people
- Sponsor
- All India Institute of Medical Sciences
Lung Cancer
EBUS-TBNA-RTE VS Radiography in Staging of NSCLC
The purpose of this study is to make a qualitative and quantitative analysis of the intrathoracic lymph nodes by CP-EBUS elastography for the first time, and to make a benign and malignant diagnosis.
- Trial name
- NCT03392506
- Testing
- EBUS-TBNA-RTE
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiayuan Sun
Multiple Pulmonary Diseases
Uncuffed Endotracheal Tube vs. no Endotracheal Tube
This is a comparison of uncuffed endotracheal tube (UCETT) vs. no endotracheal tube (ETT) in endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) procedure under moderate sedation in terms of procedure tolerance…
- Trial name
- NCT06799455
- Testing
- Endotracheal tube
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Minnesota
Sarcoidosis, Mediastinal Diseases
Endobronchial Ultrasonography in the Diagnosis of Sarcoidosis
Sarcoidosis is a benign, inflammatory condition which will typically involve the lungs and lymph glands in the chest. Diagnosis is often confirmed with bronchoscopic biopsy.
- Trial name
- NCT00373555
- Testing
- Bronchoscopy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Suspected Sarcoidosis
Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis
This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared…
- Trial name
- NCT06220526
- Testing
- endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University Health Network, Toronto
Lung Cancer
EBUS/Spectrum Analysis
To evaluate the clinical benefit of spectrum analysis of endobronchial ultrasound images of lymph nodes during EBUS TBNA for lymph node staging in patients with lung cancer.
- Trial name
- NCT01972386
- Testing
- Spectrum Image Analysis using a Linear Array Ultrasound Bronchoscope
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- University Health Network, Toronto
Endobronchial Ultrasound
HFNC Versus SOT During EBUS
Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is a routine procedure that is performed to sample mediastinal lymph nodes.
- Trial name
- NOT-EBUS (NCT05425836)
- Testing
- Standard oxygen therapy, HFNC
- Where
- 2 sites in India
- Volunteers
- 300 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Bronchopulmonary Diseases
1% vs. 2 % Lignocaine for Endobronchial Ultrasound Guided Transbronchial Needle Aspiration
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS -TBNA) is commonly performed for diagnosis of mediastinal pathologies.
- Trial name
- NCT02913300
- Testing
- Lignocaine 1% concentration solution, Lignocaine 2% concentration solution
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Procedural Sedation and Analgesia
Consent Understanding and Propofol Requirement During Endobronchial Ultrasound
The goal of this observational study is to learn whether a participant's understanding of the informed consent information is related to the amount of propofol needed during endobronchial ultrasound (EBUS).
- Conditions
- ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Procedural Sedation and Analgesia, Informed Consent
- Trial name
- NCT07677982
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Uludag University
Lung Cancer
Endobronchial Ultrasound Versus Mediastinoscopy in Patients With Non-Small Cell Lung Cancer (NSCLC)
The goal of this clinical research study is to compare 2 different methods for checking lymph glands (in the middle of the chest) for cancer cells.
- Trial name
- NCT00559611
- Testing
- Endobronchial Ultrasound, Mediastinoscopy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- M.D. Anderson Cancer Center