Clinical trials: Diverticular Disease of Colon
Colectomy, Appendicitis
Colonic Resections in Patients With Suspected Appendicitis
Although many reports have been published on colonic resections in patients with suspected appendicitis and the diseases that cause the decision to resect the colon have been identified and their proper treatments have been…
- Trial name
- NCT00888888
- Testing
- Right hemicolectomy with or without primary anastomosis
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Cirujanos la Serena
Diverticulitis
Italian Study Group on Complicated Diverticulosis
Patients were recruited over a four year period from 1996 to 1999. Those admitted in the years 1996 and 1997 were retrospectively accrued from the clinical records, while patients treated between 1998 and 1999 patients were…
- Trial name
- GISDIC (NCT01276886)
- Testing
- antibiotic, Colonic resection with or without stoma
- Where
- Italy
- Sponsor
- Gruppo Italiano per lo Studio della Diverticolite Complicata
Colon Cancer, Rectal Cancer
Compare Propofol to Fentanyl and Midazolam for Colonoscopy
The study aim is to determine if Propofol or the combination of Fentanyl and low-dose Midazolam, are equivalent for patient satisfaction and discomfort when undergoing a colonoscopy. This is a prospective randomized study of 262.
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01488045
- Testing
- Fentanyl, Propofol, Midazolam
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Trinity Health Michigan
Neoplasm, Diverticular Disease
Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery
The aim is to ascertain which method out of epidural, spinal or patient controlled analgesia (PCA) is the most appropriate in fluid optimised patients after laparoscopic colorectal surgery in terms of pain control, length of…
- Conditions
- Neoplasm, Diverticular Disease, Analgesia
- Trial name
- NCT00747292
- Testing
- epidural, PCA, Spinal
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- Minimal Access Therapy Training Unit
Colorectal Cancer, Diverticulitis, Colonic
Colorectal Omics and OfCS Proteoglycans
This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer.
- Conditions
- Colorectal Cancer, Diverticulitis, Colonic, Inflammatory Bowel Diseases, Stoma Colostomy
- Trial name
- COCO (NCT06287671)
- Testing
- Colorectal resection or stoma closure
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Sexual Function Disturbances
Preservation of Inferior Mesenteric Artery Could Improve Sexual Function After Laparoscopic Colorectal Resection for Diverticular Disease
This study aims to evaluate whether IMA sparing may represent an advantage in terms of reduced incidence and severity of sexual dysfunctions after colorectal resections for diverticular disease (DD).
- Trial name
- IMAPSEX (NCT04752241)
- Testing
- Inferior Mesenteric Artery Preservation, Inferior Mesenteric Artery Ligation
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Roma La Sapienza
Colorectal Cancer, Diverticulitis Colon
Seal-G MIST (Minimally Invasive Sealant/Spray Technology) System Safety Study [SEALAR Study]
The purpose of this study is to evaluate safety of Seal-G MIST System in reinforcing colorectal anastomosis, in subjects undergoing colorectal surgery.
- Trial name
- SEALAR (NCT03448874)
- Testing
- Seal-G MIST System
- Sponsor
- Sealantis Ltd.
Acute Uncomplicated Diverticulitis
Non-antibiotic Management in Acute Uncomplicated Diverticulitis
Diverticulitis is a common condition that causes swelling and pain in part of the colon (the large intestine). Doctors classify it as "mild" when there are no serious complications.
- Trial name
- NAMAD (NCT07625267)
- Testing
- Symptomatic treatment (ibuprofen and acetaminophen), Amoxicillin-clavulanate, Ciprofloxacin plus metronidazole
- Sponsor
- Montefiore Medical Center
Simple Diverticular Disease
Randomized Clinical Trial for the Uncomplicated Diverticulitis in Right Colon
The aim of the present study was to evaluate whether antibiotics is mandatory for the treatment of acute uncomplicated right-sided diverticulitis.
- Trial name
- NCT02314013
- Testing
- Cephalosporin + Metronidazole
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Dongtan Sacred Heart Hospital
Diverticulum, Colon, Colorectal Neoplasms
A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing device in routine clinical practice at 4-6 centers.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT01880918
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- novoGI
Diverticulitis
Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis
Patients will agree to be randomized to either surgery or observation following nonoperative management of a first episode of Hinchey II diverticulitis.
- Trial name
- NCT01986686
- Testing
- Colon resection
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Stony Brook University
Acute Diverticulitis, Diverticular Diseases
Towards a Tailored Approach for Patients With Acute Diverticulitis and Abscess Formation. A Multicenter Cohort Analysis
It is estimated that approximately 15% to 20% of the subjects with sigmoid diverticulosis will develop acute diverticulitis, with diverticular abscess as the most common complication of sigmoid diverticulitis.
- Conditions
- Acute Diverticulitis, Diverticular Diseases, Diverticulitis of Sigmoid, Acute Diverticular Perforation
- Trial name
- DivAbsc2023 (NCT06109506)
- Testing
- Conservative treatment with antibiotics and eventual percutaneous image-guided drainage of the abscess
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University of Cagliari
Colon Cancer, Rectal Cancer
Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery
The primary outcome for this study is the Numeric Pain Score (NPS) for elective patients undergoing elective colorectal surgery that have been randomized to transversus abdominis plane block or epidural anesthesia for the…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- TAP (NCT02591407)
- Testing
- TAP Block, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Trinity Health Michigan
Diverticular Disease of Colon, Colostomy - Stoma
ARES Trial: Approach to Resection and Evaluation in Severe Diverticulitis
This observational study was conducted across five surgical centers in Italy, including both academic and community hospitals, from January 2017 to December 2022.
- Conditions
- Diverticular Disease of Colon, Colostomy - Stoma, Loop Ileostomies
- Trial name
- ARES (NCT07094594)
- Where
- Italy
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
Colonic Diverticula, Angiodysplasia
Study of Hemospray for Lower Gastrointestinal Hemorrhage
This study is to evaluate the performance of Hemospray for the teatment of nonvariceal lower gastrointestinal bleeding.
- Conditions
- Colonic Diverticula, Angiodysplasia, Colonic Polyp
- Trial name
- NCT02099435
- Testing
- Hemospray
- Where
- 4 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Cook Group Incorporated
Rectal Neoplasms, Colon Neoplasms
Fluorescent Evaluation of Colorectal Anastamoses
Bowel removal is indicated for various types of colon and rectal disease, including colon cancer, rectal cancer, diverticulitis, and inflammatory bowel disease among others.
- Conditions
- Rectal Neoplasms, Colon Neoplasms, Diverticulitis
- Trial name
- NCT01424293
- Testing
- Indocyanine Green, The SPY® Intraoperative Imaging System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Maimonides Medical Center
Colonic Diverticulitis
The Out-patient, Non Antibiotic Management of Patients With Acute Uncomplicated Colonic Diverticulitis
Previous multicentre study NCT 01008488 indicates that a patient with CT-proven uncomplicated diverticulitis has a very low risk (1.4%) of developing severe complications such as perforations or abscesses.
- Trial name
- P-VOD (NCT01515150)
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Uppsala University
Colorectal Cancer, Inflammatory Bowel Diseases
Predictive Time-to-Event Model for Major Medical Complications After Colectomy
Purpose: The purpose of this study is to create prediction models for when major complications occur after elective colectomy surgery. Justification: After surgery, patients can have multiple complications.
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Diverticulitis, Colectomy
- Trial name
- NCT05150548
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 130,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diverticulitis, Colonic
Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics
The objective of this clinical trial to evaluate the effectiveness and safety of outpatient treatment without antibiotics compared to outpatient treatment with antibiotics in patients with acute uncomplicated diverticulitis.
- Trial name
- ADIANA (NCT06517264)
- Testing
- Antibiotic, Non antibiotic
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Monica Mengual Ballester