Clinical trials: Dissociation
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Borderline Personality Disorder, Dissociation
Naltrexone in the Treatment of Dissociative Symptoms in Patients With Borderline Personality Disorder
Our study aims at contributing to a valid appraisal of the magnitude of naltrexone efficacy as an antidissociative agent by using a double-blind randomized controlled trial.
- Trial name
- NCT01133301
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Dissociative Disorder
Evaluation of the Efficacy of Dissociation-Focused Cognitive Behavior Therapy
Dissociative symptoms and disorders are particularly prevalent in the general population and among people suffering from psychiatric disorders. To date, no treatment has proven effective for this type of problem.
- Trial name
- TCC-DISSO (NCT06917209)
- Testing
- CBT-CD psychotherapy
- Where
- 8 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Tours
Thin Sections, Fresh Unfixed Tissues
Tissue Sectioning by Electro-Dissociation
Currently there is no technique to produce thin (0.004-0.01 mm) serial sections of large fresh tissue specimens that are suitable for high-resolution in situ protein/gene expression studies without ice artifact or…
- Conditions
- Thin Sections, Fresh Unfixed Tissues, Fresh Unfrozen Tissues
- Trial name
- NCT01054612
- Testing
- Tissue Sectioning via Electro Erosion Process
- Sponsor
- University of Arkansas
Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage (ICH)
Sleep to Predict Recovery In Unconscious Patients With Acute Brain Injury
Severe brain injuries can leave people in states where they are unconscious or only partly aware, such as a coma. These conditions are common after injuries like head trauma or bleeding in the brain.
- Trial name
- SPRINT (NCT07794605)
- Where
- 2 sites in United States
- Volunteers
- 230 people
- Sponsor
- Columbia University
Crohn's Disease
Psychology of Crohn's Disease
The purpose of this study is to determine whether emotional processing and somatic dissociation influence IBS-like symptoms in Crohn's Disease patients.
- Trial name
- NCT01573078
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Dissociation
Effectiveness of an Online Psychoeducation Program for Improving Coping in People With a High Level of Dissociative Symptoms: A Pilot Randomized Waitlist-controlled Trial
Subject Population Our study's target population is people with pathological dissociation in the community. Research Design A pilot randomized waitlist-controlled trial will investigate the effects of an online psychoeducation…
- Trial name
- NCT05519748
- Testing
- Online psychoeducational program
- Where
- Hong Kong
- Volunteers
- 101 people
- Sponsor
- Chinese University of Hong Kong
Scapholunate Interosseous Ligament Injury, Scaphoid-Lunate Instability
Comparison of Strength, Weight Bearing, Proprioception, Reaction Time and Function in Scapholunate Instability
Scapholunate (SL) instability is the most common type of instability seen in the wrist, resulting from SLI injury or excessive mobility [1,2].
- Conditions
- Scapholunate Interosseous Ligament Injury, Scaphoid-Lunate Instability, Scapholunate Dissociation
- Trial name
- NCT07134452
- Testing
- Baseline Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Scapholunate Dissociation, Scapholunate Ligament Rupture
Scapholunate Ligament Reconstruction Using Modified Flexor Carpi Radialis Tenodesis
Retrospective study of patients who underwent a modified flexor carpi radialis (FCR) tenodesis for scapholunate ligament injury at Waldfriede Hospital during the period 2016-2026.
- Trial name
- NCT07667114
- Testing
- modified flexor carpi radialis tenodesis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Waldfriede Hospital
Post-traumatic Stress Disorder, Dissociation
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
This pilot randomized controlled trial will evaluate the feasibility and effectiveness of a mobile neurofeedback intervention for increasing maternal overall well-being, and measuring whether mothers experience any subsequent…
- Conditions
- Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior
- Trial name
- NCT05474534
- Testing
- Neurofeedback (MUSE 2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Liver Transplantation
Oxygen Dissociation Curve in Patients Undergoing Orthotopic Liver Transplantation
Hemoglobin (Hb) is the molecule responsible for the transport of oxygen (O2) to the tissues in mammals. The p50 and the Hill coefficient (HC) best describe the ODC.
- Trial name
- NCT05822570
- Testing
- Assessment of Oxygen Dissociation Curve (ODC)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University Innsbruck
Anhedonia
TMS Alteration of the Reward Positivity
The aim of this proposal is to demonstrate that stimulation of different brain regions differently affects the electroencephalographic feature known as the Reward Positivity (RewP).
- Trial name
- NCT05443256
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Sepsis, Septic Shock
Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients
Alterations of acid-base equilibrium are very common in critically ill patients and understanding their pathophysiology can be important to improve clinical treatment.
- Conditions
- Sepsis, Septic Shock, Critical Illness, Respiratory Acidosis
- Trial name
- ENTERPRISE (NCT03966664)
- Testing
- In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma., In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood, Biomolecular analysis of plasma proteins.
- Where
- 2 sites in Czechia, Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Scapholunate Dissociation
Diagnosing Dynamic Scapholunate Instability with Computer Tomography
Scapholunate instability can result in debilitating pain, dysfunction, and secondary arthritis. If treatment is required, the instability should ideally be addressed in the dynamic stage, before non-reducible non-repairable…
- Trial name
- stressct (NCT06695260)
- Testing
- CT scan
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Regionaal Ziekenhuis Heilig Hart Tienen
Family Satisfaction, Healthcaregiver Satisfaction
Benefits of the Involvement of Nurses in Meetings Between Physicians and the Families of Patients in the ICU.
When a patient is admitted to the ICU this often happens so suddenly that this can create a significant amount of stress and anxiety for family members for several reasons.
- Conditions
- Family Satisfaction, Healthcaregiver Satisfaction, Family PTSD, Family HADS
- Trial name
- NEWS (NCT01745406)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph
Hypnosis
Interest of Catalepsy in the Hypnotic Trance
Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis.
- Trial name
- CATALHYPNOANI (NCT05306262)
- Testing
- Hypnosis session, Catalepsy
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CMC Ambroise Paré
Dissociation
Mechanistic Interventions and Neuroscience of Dissociation
The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people.
- Trial name
- MIND (NCT04670640)
- Testing
- Vibration, Breath Focus, No Distractions
- Where
- 2 sites in United States
- Volunteers
- 350 people
- Sponsor
- Emory University
Traumatic Brain Injury (TBI) Patients, Severe Traumatic Brain Injury
SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury
Objective: This prospective interventional study introduces "SeeMe," an automated, high-resolution computer vision platform designed to objectively quantify microscopic, auditory command-evoked movements in patients with…
- Trial name
- NCT07560631
- Testing
- SeeMe Multimodal Auditory Command Protocol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Complete Tear of Scapholunate Ligament, Scapholunate Dissociation
Evaluation of the Surgical Proficiency and Effectiveness of the Acumed Scapholunate Repair System in Primary Scapholunate Instability Among Canadians
This study is a prospective, multi-centre, non-randomized, and non-blinded follow-up study to assess the efficacy and effectiveness of the ACUMED® Scapholunate Repair System in primary scapholunate interosseous ligament (SLIL)…
- Trial name
- CanRASL (NCT04980547)
- Testing
- ACUMED® Scapholunate Repair System Group
- Volunteers
- 50 people
- Sponsor
- University of Calgary