HypnosisCATALHYPNOANINCT05306262
Interest of Catalepsy in the Hypnotic Trance
A study testing Hypnosis session and Catalepsy in people with Hypnosis, run by CMC Ambroise Paré at 1 site in France.
Trial summary
Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis. Furthermore, it has been shown that the hypnotic trance state is accompanied by an increase in parasympathetic tone, the non-invasive measurement… Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Hypnosis
- What is being tested?
- Hypnosis session and Catalepsy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteFrance
- Study dates
- 26 May 2022to 28 May 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Healthy Volunteers
- Consent for participation
- Affiliation to the social security system
Who cannot join
- Arrhythmia (atrial fibrillation, pacemaker, defibrillator)
- Autonomic nervous system disorder (paraplegia, epilepsy, etc.)
- Pregnant or breastfeeding woman
- Patients under protection of the adults (guardianship, curators or safeguard of justice)
- Communication difficulties
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Catalepsy on the Parasympathetic Tone Assessed by ANI (Analgesia/Nociception Index) and on Absorption, Dissociation and Perception of Time During the Hypnotic Trance.
Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis. Furthermore, it has been shown that the hypnotic trance state is accompanied by an increase in parasympathetic tone, the non-invasive measurement of which is easy by the ANI monitor (Analgesia Nociception Index).
The research hypothesis is that, by adding a body dissociation, catalepsy could facilitate and intensify the hypnotic trance, the intensity of which can be monitored and is proportional to the parasympathetic tone.
Read the detailed description
After randomization, subjects will either benefit from the normal hypnotic trance, or from the hypnotic trance associated with catalepsy of the hand.
T0 = installation in a sitting position and collection of an accompanying theme T1 = induction of the hypnotic trance (closing eyes) with restitution of the theme to the patient and suggestion of comfort over a period of 5 to 10 min T2 = validation of comfort by a pre-established signal T3 = return to consciousness (opening eyes) T4 = end of questionnaire about absorption, dissociation and time perception
- Conditions
- Hypnosis
- Being tested
- Hypnosis session, Catalepsy
- Keywords
- Hypnosis, Catalepsy, Parasympathetic tone, Absorption, Dissociation, Perception of time
- Medical subject headings
- Catalepsy, Dissociative Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Hypnosis sessionProcedure or surgery
Comfort hypnosis: accompaniment of a pleasant memory.
CatalepsyOther
Catalepsy of the hand.
| Study group | Role | What they receive |
|---|---|---|
| hypnotic trance | Active comparator | Hypnosis session of comfort for 20 minutes Receives: Procedure: Hypnosis session |
| hypnotic trance + catalepsy | Experimental | Catalepsy + Hypnosis session of comfort for 20 minutes Receives: Procedure: Hypnosis session; Other: Catalepsy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Parasympathetic tone
Analgesia Nociception Index (ANI)
Measured: 30 minutes
Secondary outcomes (5)
Absorption
Numeric scale from 0 to 10 (0=not at all, 10=completely)
Measured: 30 minutes
Dissociation
Numeric scale from 0 to 10 (0=completely in the reality, 10=completely disconnected from reality)
Measured: 30 minutes
Time perception (minute)
Difference between the time of hypnosis session estimated by the patient and the actual time of hypnosis session (from closing to opening the eyes).
Measured: 30 minutes
Variation of Heart Rate (beat per minute)
Heart rate measured by a pulse oximeter
Measured: 30 minutes
Variation of Respiratory Rate (breath per minute)
Respiratory rate assessed by the investigator
Measured: 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2022
- Study start26 May 2022
- Primary completion28 May 2022
- Study completion28 May 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HypnosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- CMC Ambroise Paré
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05306262
- Sponsor's protocol ID
- 2020/03
- Acronym
- CATALHYPNOANI
- Status last verified
- Apr 2026
- First submitted
- 23 Mar 2022
- Last updated
- 8 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Boselli E, Radoykov S, Paqueron X, Virot C. Effects of hand catalepsy on subjective trance perception and relative parasympathetic tone in healthy volunteers during pleasant hypnotic session: a randomized controlled study. J Clin Monit Comput. 2024 Dec;38(6):1291-1296. doi: 10.1007/s10877-024-01178-7. Epub 2024 May 29.
PubMed 38811463
Study at a glance
From the registry record, last updated by the sponsor on 8 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Catalepsy on the Parasympathetic Tone Assessed by ANI (Analgesia/Nociception Index) and on Absorption, Dissociation and Perception of Time During the Hypnotic Trance.
- ClinicalTrials.gov ID
- NCT05306262
- Acronym / sponsor ID
- CATALHYPNOANI / 2020/03
- Conditions
- Hypnosis
- Keywords
- Hypnosis, Catalepsy, Parasympathetic tone, Absorption, Dissociation, Perception of time
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- CMC Ambroise ParéUniversity, hospital or other
- Study start
- 26 May 2022 (actual)
- Primary completion
- 28 May 2022 (actual)
- Study completion
- 28 May 2022 (actual)
- First posted
- 1 Apr 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis. Furthermore, it has been shown that the hypnotic trance state is accompanied by an increase in parasympathetic tone, the non-invasive measurement of which is easy by the ANI monitor (Analgesia Nociception Index).
The research hypothesis is that, by adding a body dissociation, catalepsy could facilitate and intensify the hypnotic trance, the intensity of which can be monitored and is proportional to the parasympathetic tone.
Detailed description
After randomization, subjects will either benefit from the normal hypnotic trance, or from the hypnotic trance associated with catalepsy of the hand.
T0 = installation in a sitting position and collection of an accompanying theme T1 = induction of the hypnotic trance (closing eyes) with restitution of the theme to the patient and suggestion of comfort over a period of 5 to 10 min T2 = validation of comfort by a pre-established signal T3 = return to consciousness (opening eyes) T4 = end of questionnaire about absorption, dissociation and time perception
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| hypnotic trance | Active comparator | Procedure: Hypnosis sessionHypnosis session of comfort for 20 minutes |
| hypnotic trance + catalepsy | Experimental | Procedure: Hypnosis session, Other: CatalepsyCatalepsy + Hypnosis session of comfort for 20 minutes |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Healthy Volunteers
- Consent for participation
- Affiliation to the social security system
Key exclusion criteria (5 listed)
- Arrhythmia (atrial fibrillation, pacemaker, defibrillator)
- Autonomic nervous system disorder (paraplegia, epilepsy, etc.)
- Pregnant or breastfeeding woman
- Patients under protection of the adults (guardianship, curators or safeguard of justice)
- Communication difficulties
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Hypnosis sessionComfort hypnosis: accompaniment of a pleasant memory. | Procedure or surgery | hypnotic trance, hypnotic trance + catalepsy |
| CatalepsyCatalepsy of the hand. | Other | hypnotic trance + catalepsy |
Primary outcome
Parasympathetic tone
Time frame: 30 minutes
Analgesia Nociception Index (ANI)
5 secondary outcomes
Absorption
Time frame: 30 minutes
Dissociation
Time frame: 30 minutes
Time perception (minute)
Time frame: 30 minutes
Variation of Heart Rate (beat per minute)
Time frame: 30 minutes
Variation of Respiratory Rate (breath per minute)
Time frame: 30 minutes
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Apr 2026.
- Results publication: PubMed 38811463Boselli E, Radoykov S, Paqueron X, Virot C. Effects of hand catalepsy on subjective trance perception and relative parasympathetic tone in healthy volunteers during pleasant hypnotic session: a randomized controlled study. J Clin Monit Comput. 2024 Dec;38(6):1291-1296. doi: 10.1007/s10877-024-01178-7. Epub 2024 May 29.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Hypnosis session and Catalepsy in people with Hypnosis, run by CMC Ambroise Paré at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Parasympathetic tone (time frame: 30 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05306262, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Apr 2026.