Clinical trials: Discogenic Pain
Discogenic Low Back Pain
PerQdisc Traditional Feasibility Trial.
This is a traditional feasibility study (TFS) study to evaluate the safety and effectiveness of the PerQdisc. The study is prospective, multicenter, and open label.
- Trial name
- NCT06860867
- Testing
- PerQdisc
- Where
- 8 sites in United States
- Volunteers
- 5 people
- Sponsor
- Spinal Stabilization Technologies
Discogenic Back Pain
FLO for Discogenic Pain
Discogenic pain is pain originating from a damaged vertebral disc and be caused by inflammation, dehydration of the nucleus pulposus, decreased disc height, annular tears and impaired mechanical function of the disc.Non-operative…
- Trial name
- NCT03644251
- Testing
- amniotic and umbilical cord matrix
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- BioTissue Holdings, Inc
Discogenic Back Pain Patients
Radiofrequency Ablation of Rammii Communicans Versus Annuloplasty in Discogenic Back Pain
Aim of the study Comparing the safety, efficacy, pain reduction, and functional disability between Ramii communicans radiofrequency versus Annuloplasty versus combined both techniques in patients with discogenic low back pain…
- Trial name
- NCT07360444
- Testing
- radiofrequency ablation of Rammii Communicans, Annuloplasty Radiofrequency Ablation
- Volunteers
- 90 people
- Sponsor
- Esraa Fathy Radwan Abd Elzaher
Chronic Pain
Study to Evaluate the Effectiveness of DRG Stimulation for Discogenic Low Back Pain
The purpose of this prospective post market observational pilot study is to evaluate the effect of DRG stimulation in the management of chronic discogenic pain in subjects who are refractory to other available treatments.
- Trial name
- NCT02587637
- Testing
- Dorsal root ganglion (DRG) stimulation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Abbott Medical Devices
Lumbar Radiculopathy
Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica
The goal of this clinical trial is to evaluate the effect of Transfer of Energy Capacitive and Resistive (TECAR) on pain, functional disability and electrophysiological parameters in adults with chronic discogenic sciatica .
- Trial name
- NCT07841405
- Testing
- Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Lower Back Pain Chronic, Lumbar Degenerative Disease
Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain
Background Degenerative disc disease (DDD) is the leading cause of lower back pain and disability, which prevalence increasing with age. When conservative treatment fails, surgical methods of spinal fusion are employed.
- Conditions
- Lower Back Pain Chronic, Lumbar Degenerative Disease, Lumbar Disc Degeneration, Degenerative Disc Disease(DDD)
- Trial name
- MID-MIS (NCT07127380)
- Testing
- Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Copernicus Memorial Hospital
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Low Back Pain
Treatment of Chronic Low Back and Lower Extremity Pain
1. To demonstrate clinically significant improvements in patients undergoing lumbar interlaminar epidurals. Improvement will be assessed in relation to the clinical outcome measures of pain and function. 2.
- Trial name
- NCT00681447
- Testing
- Lumbar Interlaminar Epidural, Lumbar Interlaminar Epidural injection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Sciatica Due to Intervertebral Disc Disorder
Effect of Sensorimotor Training on Pain and Gait Performance in Patients With Discogenic Sciatica
This study aims to investigate the effect of sensorimotor training on gait performance in patients with discogenic sciatica.
- Trial name
- NCT07805265
- Testing
- Standard physical therapy, Sensorimotor Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Low Back Pain, Low Back Pain, Mechanical
"EFFECTS OF KINESIO-TAPING ON PAIN, POSTURAL STABILITY AND FUNCTION IN PERSONS WITH DISCOGENIC LOW BACK PAIN"
Low back pain is the leading cause of disability worldwide, the prevalence of low back pain can be as high as 43%. Past research has shown the positive effects of Kinesio taping in patients with chronic and nonspecific low back…
- Trial name
- NCT05713812
- Testing
- Kinesiotaping, Control Treatment
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Foundation University Islamabad
Low Back Pain, Disc Disease
Fibrin for Chronic Multi-level Discogenic Low Back Pain
Intra-annular injections of non-autologous fibrin for moderate to severe chronic low back pain (LBP).
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Radiculopathy
- Trial name
- NCT04621799
- Testing
- Fibrin sealant
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Pauza, Kevin, MD
Low Back Pain
Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
To demonstrate clinically significant improvements or lack thereof in the caudal epidural patients with our without steroids. To evaluate differences in outcomes in patients receiving steroids compared to those patients…
- Trial name
- NCT00370799
- Testing
- Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah
Degenerative Disc Disease, Disc Degeneration
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
VIA Disc NP is a non-surgical intervention intended to supplement nucleus pulposus tissue in degenerated intervertebral discs. This is a randomized, sham-controlled, multi-center, double-blind clinical trial with an open label…
- Conditions
- Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain
- Trial name
- RESTORE (NCT06778447)
- Testing
- VIA Disc NP
- Where
- 19 sites in United States
- Volunteers
- 325 people
- Sponsor
- VIVEX Biologics, Inc.
Low Back Pain
Lumbar Fusion or Non-operative Care for Treatment of Presumed Discogenic Pain
Title and abstract 1 a. Title: Lumbar fusion or non-operative care for treatment of presumed discogenic pain. A randomized study. 1 b. Structured summary: Authors: B. Nyström, B. Schillberg, E. Svensson, T. Stiles.
- Trial name
- NCT02695576
- Testing
- Lumbar Fusion Surgery, Physiotherapy, Cognitive behavioral therapy
- Volunteers
- 74 people
- Sponsor
- Spinal Surgery Clinic, Strängnäs
Low Back Pain, Disk Prolapse
Effects of Sustained Natural Apophyseal Glides in Combination With McKenzie Extension Protocol in the Management of Discogenic Low Back Pain
Lumbar degenerative disc disease and discogenic low back pain is comparatively common and disabling musculoskeletal condition. McKenzie's extension protocol is considered to be the gold standard physical therapy treatment for…
- Conditions
- Low Back Pain, Disk Prolapse, Disk Herniated Lumbar, Sciatic Radiculopathy
- Trial name
- NCT05314049
- Testing
- Mckenzie Extension Protocol, Lumbar SNAGs, inferential therapy
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Lumbar Radiculopathy
Low Level LASER Therapy With and Without Proprioceptive Stimulation Among Discogenic Lumbar Radiculopathy Patients
The aim of this study is to evaluate the effects of low level laser therapy with and without proprioceptive stimulation on somatosensation, pain and gait parameters in patients with discogenic lumbar radiculopathy.
- Trial name
- NCT05953727
- Testing
- Low level laser therapy with proprioceptive stimulation, Low level laser therapy without proprioceptive stimulation
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Discogenic Pain
Safety and Efficacy of PRP for Treatment of Disc Pain
This is a multi-center, randomized, controlled, double-blind clinical trial comparing hemocyte autograft (platelet rich plasma) to control injection (placebo) in subjects with reported cervical, thoracic or lumbar pain for at…
- Trial name
- NCT04064866
- Testing
- High yield pure PRP, ProPlaz PPC
- Where
- 7 sites in United States
- Volunteers
- 27 people
- Sponsor
- Neurological Associates of West Los Angeles
Discogenic Pain, Low Back Pain
Value of Functional Anesthetic and Provocative Discography in the Surgical Treatment of Discogenic Pain
Although discography and spinal imaging techniques, either alone or in combination, are commonly used to diagnose discogenic pain, their exact role in predicting surgical results are poorly defined.
- Trial name
- NCT01077947
- Testing
- Functional anesthetic discography, Provocative Discography
- Sponsor
- Northwestern University
Low Back Pain, Disk Prolapse
Effects of Physical Therapy on Improving Disc Height, Postural Stability, Pain and Function in Persons With Discogenic Low Back Pain
Lumbar degenerative disc disease and discogenic low back pain is comparatively common and disabling musculoskeletal condition, however there is no conclusive evidence regarding the positive effects of conservative physical…
- Trial name
- NCT05326594
- Testing
- Mckenzie Extension Protocol, Lumbar SNAGs, Inferential therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Lumbar Discogenic Pain
The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain
This experimental use umbilical cord mesenchymal stem cells in treatment of the early stage of lumbar discogenic pain (endogenous pain of the disc) to evaluate its safety and efficacy.
- Trial name
- NCT04104412
- Testing
- human umbilical cord mesenchymal stem cell
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.