Clinical trials: Dental Surgeries, open to volunteers
Maxillary Deficiency, Bone Resorption
Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery
This study evaluates the Bone Ring Technique, a single stage procedure that combines external sinus floor elevation and dental implant placement using an autogenous bone ring harvested from the chin.
- Trial name
- BRT-SINUS (NCT07619846)
- Testing
- Bone Ring Technique (BRT)
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University
Pulp Necrosis, Apical Periodontitis
Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment.
Bacteria inside the root canal are a major cause of tooth infections. If they are not completely removed, the infection may continue even after root canal treatment.
- Trial name
- NCT07688005
- Testing
- Sodium Hypochlorite 3% Solution, Emblica officinalis Solution
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Partial Edentulism Class 1 or Class 2
Comparative Evaluation of Artificial Intelligence-Assisted Versus Conventional Guided Implant Planning in Free End Saddle Cases
This study aims to compare the accuracy and clinical performance of artificial intelligence (AI)-assisted implant planning with conventional human-based implant planning in patients presenting with free-end saddle edentulous…
- Trial name
- NCT07891442
- Testing
- Dental implant palcement
- Volunteers
- 20 people
- Sponsor
- Mariam Morcos Nasr
Dental Implant
Apically Positioned Flap vs Rolled Flap for Soft Tissue Management During Implant Second-Stage Surgery
Patients are being asked to consider joining a research study that looks at two different ways dentists uncover dental implants during a small gum surgery.
- Trial name
- NCT07595211
- Testing
- Apically Positioned Flap (APF), Rolled Flap Technique (RFT)
- Volunteers
- 16 people
- Sponsor
- Ohio State University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Implant, Implant Therapy
Do Immediate Digital Workflows Increase Patient Value?
This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant…
- Conditions
- Dental Implant, Implant Therapy, Immediate Dental Implant Placement, Delayed Implant
- Trial name
- ITI PROM RCT (NCT07656597)
- Testing
- Immediate digital posterior implant workflow, Delayed digital posterior implant workflow
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 50 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Periapical Periodontitis, Pulpitis
Clinical and Radiographic Evaluation of Primary Endodontic Treatment and Non-surgical Endodontic Retreatments
Background: Pulpitis and apical periodontitis are inflammatory conditions of the dental pulp and periapical tissues, primarily caused by microbial invasion.
- Trial name
- CR-ET (NCT07418840)
- Testing
- Root canal treatment and non surgical endodontic retreatment
- Volunteers
- 75 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vertical Bone Defects, Missing Tooth/Teeth
Effect of Changing Grafting Sequences During Sinus Lifting & Simultaneous Implant Placement in the Gained Bone Using Customized Surgical Guide
The aim of this randomized clinical trial is to evaluate the effect of changing the sequence of bone grafting during maxillary sinus lifting and simultaneous dental implant placement.
- Trial name
- NCT07816107
- Testing
- Traditional sequence, Modified sequence
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Periodontitis
Performance of the Treatment of Periodontitis According to the Bioperio® Protocol
This multicenter, prospective, single-arm observational study evaluated the clinical performance of the Bioperio® protocol, a standardized, patient-centered framework for managing periodontitis.
- Trial name
- BIOPERIO (NCT07507474)
- Testing
- Periodontal non surgical treatment, Oral Hygiene Instructions, Surgical Periodontal Treatment
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- University of Pisa
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Tooth Extraction, Postoperative Care
Effectiveness of Telephonic and Digital Postoperative Follow-up Communication Strategies on Patient Compliance, Clinical Recovery, and Quality of Life After Dental Extraction
Effectiveness of Telephonic and Digital Postoperative Follow-up Communication Strategies on Patient Compliance, Clinical Recovery, and Oral Health-related Quality of Life Following Dental Extraction (CONNECT Study - CONtinuous…
- Conditions
- Tooth Extraction, Postoperative Care, Patient Compliance
- Trial name
- CONNECT (NCT07751822)
- Testing
- Telephonic Postoperative Follow-up, Digital Postoperative Follow-up, Standard Postoperative Care
- Where
- Saudi Arabia
- Volunteers
- 216 people
- Sponsor
- King Saud University
Dentofacial Abnormalities, Dentofacial Deformities
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but…
- Conditions
- Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion
- Trial name
- OSP (NCT04117360)
- Testing
- Orthognathic surgery and Orthodontics
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Keratinized Mucosa Deficiency, Peri-implant Soft Tissue
Apical Flap Repositioning vs. Mucosa Excision With Free Gingival Grafts for Peri-Implant Keratinized Mucosa Augmentation
The goal of this clinical trial is to learn which surgical technique works better to increase the amount of firm gum tissue (called keratinized mucosa) around dental implants in adults.
- Conditions
- Keratinized Mucosa Deficiency, Peri-implant Soft Tissue, Dental Implants
- Trial name
- FGGIF (NCT07772414)
- Testing
- Free gingival graft with apical flap repositioning, Free gingival graft with vestibular mucosa excision
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Mucogingival Defects, Pontic Site Development
Pontic Site Development With or Without Fixed Partial Denture
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects.
- Conditions
- Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
- Trial name
- Pontic Site (NCT07535060)
- Testing
- Connective Tissue Graft (CTG)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Periodontitis and Treatment Need
Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment
Periodontitis is a multifactorial, non-infectious disease that can lead to tooth loss if left untreated. Advanced stages of periodontitis can affect chewing ability, nutritional status, and quality of life.
- Conditions
- Periodontitis, Periodontitis and Treatment Need, Periodontal Disease, Periodontal Pocket
- Trial name
- NCT07822269
- Testing
- Mechanical debridement and dental plaque sample collection with dental loupe, Mechanical debridement and dental plaque sample collection with dental microscope
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Dental Implant, Guided Surgery Accuracy
Accuracy of Static Guided Implant Surgery: 3D-printed vs Milled Surgical Guides
Dear Patient, You are invited to participate in a clinical study. To understand the study, please carefully review the following information. If you have any questions, feel free to ask the dentist leading the study.
- Trial name
- NCT06819995
- Testing
- Static guided implant placement with a 3D printed guide, Static guided implant placement with a milled guide
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universidad Complutense de Madrid
Bone Augmentation
Evaluation of the Safety and Performance of the Neobone®: A Prospective Observational Study in Dental Area
This study aims to collect real-world clinical data to gather information on the performance and safety of the Neobone® when used according to its intended purpose and current clinical applications.
- Trial name
- NeoDent01 (NCT07179497)
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Bioceramed
Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children
Evaluating Operation Calm With Children, Parents, and Clinicians
Operation Calm is a single-arm, mixed-methods feasibility study evaluating a virtual reality (VR) nature-based mindfulness intervention with children and adolescents aged 6-17 years, parents, and clinicians.
- Conditions
- Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children, Procedural Anxiety
- Trial name
- NCT07694934
- Testing
- Operation Calm EEMCF-VR
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McGill University