Clinical trials: Dental Erosion
Obesity, Dental Erosion
Salivary Function and Dental Changes During GLP-1 Therapy
People who use glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and tirzepatide, may experience changes in their oral health.
- Conditions
- Obesity, Dental Erosion, Saliva Collection, Saliva Altered
- Trial name
- NCT07720466
- Testing
- Unstimulated Whole Saliva Collection, Salivary Analysis, Oral Examination and BEWE Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Dental Erosion, Erosive Tooth Wear
Quantitative In Vivo Monitoring of Early Erosion-Associated Enamel Optical Changes Using Swept-Source Optical Coherence Tomography.
This study aims to evaluate the ability of swept-source optical coherence tomography (SS-OCT) to detect early enamel optical changes associated with erosive tooth wear under clinically relevant in vivo conditions.
- Trial name
- NCT07690644
- Testing
- Swept-Source Optical Coherence Tomography (SS-OCT), Orange Juice Erosive Challenge, Sugar-Free Chewing Gum Stimulation
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Obesity, Oral Diseases
Obesity and Oral Diseases in Adult Patients
Overweight and obesity are among the major chronic disorders of the 21st century and one of the fastest growing health problems worldwide.
- Conditions
- Obesity, Oral Diseases, Periodontitis, Dental Caries
- Trial name
- ObOd (NCT04602572)
- Testing
- Lifestyle course., Bariatric surgery.
- Volunteers
- 400 people
- Sponsor
- University of Bergen
Dental Caries in Children, Tooth Erosion
3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children
This study focuses on assessing dental caries, erosive tooth wear, and fluorosis in primary teeth using a 3D intraoral digital scanner.
- Conditions
- Dental Caries in Children, Tooth Erosion, Fluorosis, Dental, Dental Caries
- Trial name
- NCT06829550
- Testing
- indirect- 3D digital scanning
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries, Tooth Demineralization
Kissing as a Protective Factor Against Acidic pH in Saliva
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities.
- Conditions
- Dental Caries, Tooth Demineralization, Teeth Erosion Limited to the Enamel
- Trial name
- NCT06501729
- Testing
- Kiss
- Where
- Ecuador
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Dental Erosion
Effect of Smoking on Saliva Composition and the Development of Dental Erosion
The aim of this study is to investigate whether smoking is associated with changes in salivary composition and/or predisposition to erosion.
- Trial name
- NCT04208802
- Testing
- Use of fluoridated toothpaste, Wearing of an intraoral device with bovine tooth samples, Wearing of an intraoral device with resin samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Dental Caries, Dental Erosion
Maintaining Oral Health With Bio-products
This study will follow a randomised, double-blind, cross-over design. Participants will use mouth rinses containing plant extracts and/or fluoride, as well as a mouth rinse containing only water (placebo).
- Trial name
- NCT04033263
- Testing
- Mouth rinse 1, Mouth rinse 2, Mouth rinse 3
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gastro Esophageal Reflux, Dental Erosion
Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite
The aim of the present study is to evaluate dental erosion in patients with gastroesophageal reflux disease (GERD). Patients consenting to participate to the study will undergo periodontal evaluation at the baseline.
- Trial name
- NCT05371717
- Testing
- Domiciliary use of Biorepair Total Protection + Biorepair Shock Treatment, Biorepair Total Protection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Primary Ciliary Dyskinesia, Caries,Dental
Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia
The aim of this study is to compare the oral health findings, salivary parameters and pediatric oral health related quality of life of children with Primary Ciliary Dyskinesia (PCD) with healthy children
- Conditions
- Primary Ciliary Dyskinesia, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06618209
- Testing
- physical and chemical methods, biochemical methods, Oral Findings
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Erosion
Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study
Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion.
- Trial name
- NCT02780973
- Testing
- Wearing of an intraoral device with bovine tooth samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Dental Erosion
The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion
Dental erosion happens when the teeth lose some of their parts because of acid from the things people eat and/or drink or even from stomach. It can make teeth hurt and become sensitive.
- Trial name
- NCT06171594
- Testing
- Chlorhexidine mouthwash
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Dental Erosion
The Effect of Nitrate Supplement on the Oral Microbiome and Saliva in Dental Erosion
Dental erosion happens when teeth lose some of their parts because of acid from the things people eat and/or drink or even from their stomach. It can make their teeth hurt and become sensitive.
- Trial name
- NCT06156618
- Testing
- Nitrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Dental Erosion
A New Protocol for the Management of Dental Erosion in Rugby Players
The aim of the present study is to provide a new domiciliary oral care treatment for enamel remineralization in rugby players patients using mouthguards.
- Trial name
- NCT05140538
- Testing
- SRP + toothpaste + mouthwash, SRP + toothpaste
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dental Erosion
12 Months Clinical Follow-up of Non-Carious Cervical Lesions Restored With New Injectable Composite
Non-carious cervical lesions are defined as loss of pathological material not associated with caries in the enamel-cement junction of the tooth.
- Trial name
- NCT04095520
- Testing
- Laser Etching, Phosphoric acid etching
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Obesity, Obesity, Childhood
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations.
- Conditions
- Obesity, Obesity, Childhood, Tooth Wear, Tooth Erosion
- Trial name
- NCT05146557
- Testing
- Dental examination
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dental Erosion, Gastroesophageal Reflux
Gastro-oesophageal Reflux in Oligosymptomatic Patients With Dental Erosion
Dental erosions, the chemical dissolution of enamel without bacterial involvement, are considered to be an established complication of gastroesophageal reflux disease (GERD) by the Montreal global consensus statement.
- Trial name
- NCT02087345
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Brain-Gut Research Group
Dental Erosion
Dental Erosion in Patients With Gastro-oesophageal Reflux
Not only caries but also exposure to acids can lead to loss of tooth structure. This acid-related tooth structure loss is defined as dental erosion.
- Trial name
- NCT02775149
- Testing
- Collection of saliva samples, Visual detection of BEWE-index
- Volunteers
- 30 people
- Sponsor
- University of Göttingen
Tooth Erosion, Tooth Wear
Association Between Erosive Tooth Wear Progression and Dietary Risk Factors.
Study to determine if whether or not exist an association between the tissue loss (ETW progression) and the frequency of an acidic diet.
- Conditions
- Tooth Erosion, Tooth Wear, Erosion, Dental Erosion
- Trial name
- NCT04586322
- Testing
- No intervention, (observational study).
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Ghent
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months
This study aims to assess the impact of a brief home-visiting module, called "Family Spirit Nurture" (FSN), on American Indian (AI) parent feeding practices associated with increased risk for early childhood obesity, with a…
- Conditions
- Obesity, Water; Lack of, Breast Feeding, Tooth Erosion
- Trial name
- NCT03101943
- Testing
- Family Spirit Nurture (FSN), Control Program, Water Delivery
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health