Clinical trials: Dacryocystorhinostomy
Dacryocystorhinostomy, Hydroxybutyl Chitosan
Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis
Endoscopic dacryocystorhinostomy (En-DCR) has the advantages of less surgical trauma, shorter time, less postoperative bleeding, faster recovery, and no skin scars.
- Conditions
- Dacryocystorhinostomy, Hydroxybutyl Chitosan, Fluorouracil, Chronic Dacryocystitis
- Trial name
- NCT06175676
- Testing
- Hydroxybutyl chitosan, 5-Fluorouracil, Gelatin Sponge Sheet
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Dacryocystitis, Dacryocystitis; Chronic
Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each Other
The goal of this observational study is to investigate etiology and pathogenesis of nasolacrimal duct obstruction and dacryocystitis in different adult clinic groups.
- Conditions
- Dacryocystitis, Dacryocystitis; Chronic, Dacryocystorhinostomy, Epiphora
- Trial name
- NCT06810089
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Uludag University
Patient With Nasolacrimal Duct Obstruction, External Dacryocystorhinostomy Operation
Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation
Bleeding is one of the important complications during Dacryocystorhinostomy, which dissatisfy ophthalmic surgeon, reduces surgical field visualization, and increases the duration of surgery Thus, the management of this…
- Trial name
- NCT05241054
- Testing
- Bupivacaine, Nitroglycerine, Propofol
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Mansoura University
Anxiolytic Effect, Virtual Reality Immersion
Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery
The aim is to investigate the anxiolytic effect, and hemodynamic stability of using virtual reality immersion in adult patients undergoing Dacryocystorhinostomy (DCR) operation under general anesthesia and to compare its effect…
- Conditions
- Anxiolytic Effect, Virtual Reality Immersion, Midazolam, Premedication
- Trial name
- NCT07050095
- Testing
- Virtual Reality Group, Midazolam Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Dacryocystitis
Analgesic Efficacy of Pre-operative Oral Pregabalin in Dacryocystorhinostomy Surgery
This study is conducted to evaluate the effects of preoperative oral pregabalin on postoperative pain and analgesic requirements in patients undergoing DCR surgery.
- Trial name
- NCT05455944
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Airway Devices
Laryngeal Mask Airway Versus Air Q Laryngeal Airway
Nowadays, supraglottic airway devices are simple and effective alternatives to endotracheal intubation. Both laryngeal mask airway LMA and air-Q airway are supraglottic airway devices that can be used to maintain and protect…
- Trial name
- NCT04021407
- Testing
- LMA group, AirQ group
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Nasolacrimal Duct Obstruction
A Comparison of Endonasal Dacryocystorhinostomy With and Without Silicone Tubes
Aim of study is to investigate whether the use of silicone tubes in endonasal DCR surgery increases the success rate and / or complication rate compared to surgery without tubes.
- Trial name
- NCT00784992
- Testing
- Endonasal dacryocystorhinostomy
- Where
- 2 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nasolacrimal Duct Obstruction, Dacryocystorhinostomy
Amniotic Membrane for Dacryocystorhinostomy
This study aims to compare the success rate of external dacryocystorhinostomy with and without amniotic membranes in patients with nasolacrimal duct obstruction.
- Trial name
- AMDCRex (NCT06226181)
- Testing
- Dacryocystorhinostomy and amniotic membrane, Conventional dacryocystorhinostomy
- Where
- Mexico
- Volunteers
- 22 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Chronic Dacryocystitis
The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy
To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal…
- Trial name
- NCT06551766
- Testing
- Photosensitive hydrogel, 6-0 absorbable stitches
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Epiphora, Dacryocystorhinostomy
SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction
This project aims to test whether a newly designed lacrimal stent - the SlitStent - when placed into the lacrimal system in the standard fashion following a DCR surgery, will provide good symptomatic relief for epiphora and be…
- Trial name
- SLINDO (NCT03705000)
- Testing
- Slit Stent II, BIKA for DCR
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Gardner
Dacryocystitis; Chronic
Nasolacrimal Sac Biopsy in Endoscopic Dacryocystorhinostomy
During dacryocystorhinostomy (DCR), the lacrimal sac wall biopsy is not routinely performed, but it is recommended if there is a suspicion of underlying disease other than preoperatively or intraoperatively chronic inflammation.
- Trial name
- NCT04793230
- Testing
- biopsying
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Nasolacrimal Duct Obstruction
The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study
The most important symptoms of nasolacrimal duct obstruction are excessive tearing and mucoid discharge. The proposed treatment in this regard is dacryocystorhinostomy (DCR) surgery.
- Trial name
- NCT06346561
- Testing
- Dexmedetomidine, Labetalol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Epiphora
The Safety and Efficacy of Lacrimal Silicone Intubation for the Management of Epiphora
The purpose of study is to investigate the safety and efficacy of lacrimal silicone intubation for the management of epiphora.
- Trial name
- NCT01010659
- Testing
- Lacrimal Tube
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Aurolab
Acquired Nasolacrimal Duct Obstruction
Evaluation of Different Methods of Posterior Flap Management in External Dacryocystorhinostomy
The aim of DCR is to form a new, mucosa-lined pathway between the lacrimal sac and the nasal cavity where tears can bypass a lacrimal obstruction and drain directly in the nose.
- Trial name
- NCT06530264
- Testing
- DCR
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Endonasal Dacryocystorhinostomy
Endonasal Dacryocystorhinostomy and Evolution of the Stoma Size
Dacryocystorhinostomy (DCR) is a procedure of choice for nasolacrimal duct obstruction. Endonasal procedures for DCR were described as early as 1893 by Caldwell.
- Trial name
- EndoDCRevol (NCT04054791)
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Synechia After DCR
Endoscopic DCR With and Without Internal Nasal Splint
This study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates.
- Trial name
- NCT07605026
- Testing
- Endoscopic DCR with putting internal nasal splint, Endoscopic DCR without putting internal nasal splint
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Kafrelsheikh University
Effects of; Anesthesia, Local,Pain,in DISE
Anesthetic Approaches for Dacryocystorhinostomy Surgery: The Effect of Adding Local Anesthesia to General Inhalational Anesthesia
To Study the effect of combination of of general anesthesia and local anesthesia in anesthesia for external dacryocystorhinostomy and assess quality of the procedure
- Trial name
- NCT04300595
- Testing
- Combination of General anesthesia and local anesthesia in dacryocystorhinostomy surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Hemodynamic Effect, Dexmedetomidine
Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia
This study aims to compare the hemodynamic effect of dexmedetomidine and magnesium sulphate as an adjuvant to lidocaine in preemptive peribulbar block in patients undergoing Dacryocystorhinostomy (DCR) under general anaesthesia…
- Conditions
- Hemodynamic Effect, Dexmedetomidine, Magnesium Sulphate, Lidocaine
- Trial name
- NCT07675616
- Testing
- Lidocaine + Dexmedetomidine, Lidocaine + Magnesium sulphate, Lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Dacryocystorhinostomy, Sedation
Controlled Sedoanalgesia in External DCR Surgery
In our study, we aim to compare general anesthesia and controlled sedoanalgesia methods in dacryocystorhinostomy (DCR) surgery in terms of hemodynamic data, bleeding amount, postoperative complications (bleeding, pain, etc.) and…
- Conditions
- Dacryocystorhinostomy, Sedation, General Anesthesia
- Trial name
- NCT05397301
- Testing
- Controlled sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Anesthesia
Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy
Dacryocystorhinostomy aims to create a channel between the lacrimal sac and nasal mucosa to relieve nasolacrimal duct occlusion.
- Trial name
- NCT05507476
- Testing
- Desmopressin Acetate Nasal, 10 μg/0.1 ml per spray, Epinephrine topical 1:100,000 Nasal Packs
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University