Clinical trials: Cystoid Macular Edema
Vitrectomy, Macular Pucker
Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.
Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg inserts following 27 gauge vitrectomy with internal limiting membrane peel
- Conditions
- Vitrectomy, Macular Pucker, Retinal Edema
- Trial name
- NCT04501367
- Testing
- Dexamethasone Intracanalicular Insert, 0.4 mg, Prednisone acetate 1%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kovach Eye Institute
Diabetic Macular Edema, Macular Edema, Cystoid
Effect of Intravitreal Long Acting Dexamethasone Implant, Ozurdex in Patients With Diabetic Macular Edema
This study is undertaken to determine the effect of intravitreal long acting dexamethasone implant,(Ozurdex®)in patients with diabetic macular edema.Diabetic macular edema is important cause of visual impairment in patients with…
- Conditions
- Diabetic Macular Edema, Macular Edema, Cystoid, Vision Disorders, Clinically Significant Macular Edema
- Trial name
- NCT01698749
- Testing
- long acting intravitreal dexamethasone implant
- Where
- India
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Age Related Macular Degeneration, Diabetic Retinopathy
Effect of Video Viewing on Intravitreal Injection Experience
Study Objective The goal of this clinical trial is to evaluate whether viewing a procedural video can improve the patient experience and reduce the incidence and severity of subconjunctival hemorrhage in individuals undergoing…
- Conditions
- Age Related Macular Degeneration, Diabetic Retinopathy, Choroidal Neovascularization, Retinal Vein Occlusion
- Trial name
- NCT07002372
- Testing
- Procedure video viewing
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cystoid Macular Edema, Cataract
PRevention of Macular EDema After Cataract Surgery
Cystoid macular edema (CME) is a common cause of vision loss after cataract surgery. In the last few years, several new treatments have been tried to address the problem of CME after cataract surgery in diabetic and non-diabetic…
- Conditions
- Cystoid Macular Edema, Cataract, Diabetes Mellitus
- Trial name
- PREMED (NCT01774474)
- Testing
- Bromfenac, Dexamethasone, Bevacizumab
- Where
- 16 sites in Austria, Belgium and 5 more
- Volunteers
- 1,127 people
- Sponsor
- Maastricht University Medical Center
Pseudophakic Cystoid Macular Edema
Optical Coherence Tomography Angiography and Pseudophakic Cystoid Edema
This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography
- Trial name
- NCT05117411
- Testing
- OCTA and pseudophakin cystoid edema
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federico II University
Macular Edema, Cystoid
Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling
Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for…
- Trial name
- NCT04472039
- Testing
- optical coherence tomography (OCT)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
CYSTOID MACULAR EDEMA
Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide
This is an open-label, Phase I/II study evaluating intravitreal ranibizumab (R) vs. intravitreal Triesence (triamcinolone acetonide) (T) in subjects with acute pseudophakic cystoid macular edema (CME).
- Trial name
- NCT02294656
- Testing
- Ranibizumab,, Triamcinolone acetonide
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Soll Eye
Post-surgical Cystoid Macular Edema (PSCME)
Treatment of Post-surgical Cystoid Macular Edema With Topical Steroids Trial (TEMPEST-1)
The purpose of this study is to compare the change in visual acuity of patients with post surgical cystoid macular edema who will be treated with two different regimens.
- Trial name
- TEMPEST (NCT01769352)
- Testing
- PredA + Kelac
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Johns Hopkins University
Patient Preference, Patient Outcomes
The PRIME Study: A Randomized, Controlled, Prospective Study
To investigate the outcomes of patients undergoing bilateral RLE surgery with treatment of dexamethasone intracanilicular insert compared to topical standard care steroid.
- Conditions
- Patient Preference, Patient Outcomes, Post-Operative Inflammation, Grade of Post-Operative Cystoid Macular Edema
- Trial name
- NCT04549935
- Testing
- Dextenza, Topical Prednisolone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision - MT
Intravitreal Injection, Ocular Rinse
The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections
This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.
- Conditions
- Intravitreal Injection, Ocular Rinse, Age-Related Macular Degeneration, Diabetic Macular Edema
- Trial name
- NCT05615805
- Testing
- OSDI questionnaire, SPEEDII questionnaire
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Uveitis
Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment
The purpose of this study is to collect data on patients with severe uveitis that have required re-implantation of the sustained-release fluocinolone drug delivery device due to depletion of study drug in their previous implanted…
- Trial name
- NCT00543296
- Testing
- 0.59 mg Fluocinolone Acetonide implant
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Diabetic Macular Edema, Cystoid Macular Edema, Chorodial Neovascularzation, Posterior Uveitis
Suprachoroidal Injection of Triamcinolone Acetonide Using Custom Made Needle to Treat Retinal Disorders
Injection in the Suprachoroidal space has potential of increasing the efficacy of the drug upto six times with direct effect on retinal tissues sparing the crystalline lens and trabecular meshwork.
- Trial name
- NCT03606733
- Testing
- Custom suorachoroidal needle
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Marashi Eye Clinic
Macular Edema, Cystoid
Randomized Trial of Acetazolamide for Uveitis-Associated Cystoid Macular Edema
To test the efficacy of acetazolamide for the treatment of uveitis-associated cystoid macular edema.
- Trial name
- NCT00000115
- Testing
- Acetazolamide
- Sponsor
- National Eye Institute (NEI)
Cystoid Macular Edema, Diabetic Macular Edema
Variable Interval Versus Set Interval Aflibercept for DME
The purpose of this study is to compare the safety and efficacy of intravitreal Eylea injections at a set interval, versus a variable dosing schedule (likely longer than one month), based on a specific individual's disease…
- Trial name
- EVADE (NCT02392364)
- Testing
- Intravitreal Aflibercept Injection
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- California Retina Consultants
Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), Descemet Membrane Endothelial Keratoplasty (DMEK)
DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)
The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients…
- Trial name
- DMEC (NCT05072262)
- Testing
- Nepafenac Ophthalmic, Dexamethasone Ophthalmic
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Cystoid Macular Edema, Uveitis
Vitamin E to Treat Uveitis-Associated Macular Edema
This study will evaluate whether vitamin E can help treat swelling of the macular area of the retina (the back part of the eye) associated with uveitis (inflammatory eye disease).
- Trial name
- NCT00021645
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Cystoid Macular Edema,, Retinal Thickening
Bromfenac BID Plus Prednisolone Acetate BID Versus Bromfenac BID Plus Prednisolone QID for the Prevention of Cystoid Macular Edema and Retinal Thickening
The objective of this study is to determine if twice-daily dosing of prednisolone (Pred Forte) is as effective as four-times-daily dosing of prednisolone for the prevention of retinal thickening and cystoid macular edema (CME)…
- Trial name
- NCT00469781
- Testing
- 2. Xibrom (Bromfenac), 1. Pred Forte
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Center For Excellence In Eye Care
Macular Edema, Cystoid, Vision Disorders
Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema
This study is undertaken to determine the effect of intravitreal long acting dexamethasone implant, (Ozurdex®) in improving outcome of cataract surgery in patients with diabetic macular edema.
- Conditions
- Macular Edema, Cystoid, Vision Disorders, Diabetic Macular Edema, Cystoid Macular Edema Following Cataract Surgery
- Trial name
- NCT01546402
- Testing
- Dexamethasone Drug delivery system (Ozurdex), Cataract surgery
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative
Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema
The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to…
- Trial name
- LEOPARD (NCT05608837)
- Testing
- OCS-01
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Quan Dong Nguyen
Macular Edema, Cystoid, Retinal Vein Occlusion
The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study
The SCORE Study will compare the effectiveness and safety of standard care to intravitreal injection(s) of triamcinolone for treating macular edema (swelling of the central part of the retina) associated with central retinal vein…
- Trial name
- SCORE (NCT00105027)
- Testing
- Standard Care, intravitreal triamcinolone injection
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- The Emmes Company, LLC