Clinical trials: Crying
Infantile Colic
Clinical Trial of L. Reuteri in Infantile Colic 2017
RCT to evaluate the safety and efficacy of Lactobacillus reuteri DSM 17938 to significantly reduce the duration of crying time and fussines in infants from 15days to 4 months of age with colic, feed with human milk (30% sample)…
- Trial name
- Colic2017 (NCT03360253)
- Testing
- L. reuteri DSM 17938 in drops
- Where
- Mexico
- Volunteers
- 244 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Excessive Crying, Prolonged Pain
Assessment of Prolonged Pain in Infants With Excessive Crying: Contribution of Infrared Thermal Imaging - The NEOTHERM Pilot Study
NEOTHERM is a multicenter, prospective, observational pilot study examining whether infrared thermal imaging (ITI) can contribute to the assessment of prolonged pain in infants with excessive crying.
- Trial name
- NEOTHERM (NCT07693179)
- Where
- 3 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Saint-Denis
Shaken Baby Syndrome, Crying
Effects of PURPLE Cry Intervention
The proposed study is designed to investigate whether the PURPLE Crying program attains efficacy by optimizing the neural response in the anterior insula, and augmenting activity in regions of the brain known to be important for…
- Conditions
- Shaken Baby Syndrome, Crying, Trauma
- Trial name
- NCT02227979
- Testing
- The Purple Cry Intervention, Control Intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Emory University
Hemifacial Microsomia, Facial Nerve Paralysis
Treatment for "Asymmetric Crying Facies"
This study focuses on children with hemifacial microsomia (HFM), a common congenital craniofacial deformity caused by abnormal development of the first and second branchial arches.
- Trial name
- NCT07802639
- Testing
- Botulinium toxin type A injection
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaolei Jin
Infantile Colic
The Effect of Probiotics in Infantile Colic
Academic, independent, non-commercial, multicenter study sponsored by the Department of Translational Medical Sciences (DISMET), University of Naples Federico II.
- Trial name
- CSUB0214 (NCT07894445)
- Testing
- Probiotic: L. reuteri DSM 17938 + BG-R46, total 2 × 10⁸ CFU/day
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Nursing Caries
Heel Warming With Mild and Hot Thermofor Applied Before Heel Lance
Heel warming with thermophor during heel blood collection is a cost-effective and easy-to-apply method. In previous studies, it has been shown that applying heat to the heel reduces the pain of taking heel blood, increases…
- Trial name
- NCT05228366
- Testing
- Heel warming with mild thermofor group, Heel warming with hot thermofor group, Ineffective heel warming with thermofor group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Newborn
The Efficacy of Non-pharmacological Interventions on Pain Levels, Crying Times and Voice Decibels in Newborns
This study aimed to investigate and compare the effects of different non-pharmacological interventions (kangaroo care, holding on mother's lap, white noise listening, ambient sound listening) on newborns' crying times, voice…
- Trial name
- NCT04033874
- Testing
- kangaroo care, holding on the mother's lap, white noise listening
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Infantile Colic
Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic
This is a double-blind, randomized, placebo-controlled, parallel-group study in infants with colic with the primary objective to evaluate crying and fussing time.
- Trial name
- NCT06462651
- Testing
- L. reuteri
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- BioGaia AB
Pain, Acute, Newborns
Effect of Kangaroo Care and Swaddling Methods on Pain Level and Crying Time During Heel Blood Collection
This prospective study is planned as a randomized controlled study with the purpose of determining the effect of kangaroo care and swaddling methods on pain levels and crying times by newborns during heel blood collection.
- Conditions
- Pain, Acute, Newborns, Crying
- Trial name
- NCT06350071
- Testing
- Kangaroo Care, Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Newborn
Are Parents Privileged Listeners Their Baby ?
The crying baby is a sound signal including information relating to this individual identity or related to its physiological or motivational state.
- Trial name
- BABIES_CRY (NCT01732978)
- Testing
- Crying record
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infantile Colic, Microbial Colonization
The Effect of Probiotic Added to Maternal Diet on Infantile Colic and Intestinal Microbiota Content
This study aims to investigate the effect of probiotic added to the diet of mothers on infantile colic in the postpartum period and the content of the neonatal intestinal microbiota.
- Conditions
- Infantile Colic, Microbial Colonization, Crying
- Trial name
- NCT04374955
- Testing
- Activia Probiotics Shot, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Halic University
Pseudobulbar Affect (Involuntary Laughing and/or Crying)
Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)
6 month study of NUEDEXTA ® (Dextromethorphan Hydrobromide and Quinidine Sulfate) for the treatment of Pseudobulbar Affect (PBA) in Nursing Home Patients.
- Trial name
- NCT02496039
- Testing
- NUEDEXTA®
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Avanir Pharmaceuticals
Abuse, Child, Crying
Take 5 + Audio Clip Randomized Control Trial
At Yale New Haven Hospital, parents on the postpartum ward receive a Take 5 program to help train and prepare parents for strategies to manage their infant's crying.
- Conditions
- Abuse, Child, Crying, Parent-Child Relations
- Trial name
- NCT04608877
- Testing
- Take 5 and Audio Clip, Take 5 Only
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yale University
Crying Time in Colicky Infants
Effects on Crying Time in Colicky Infants With the Supplementation of Lactobacillus Reuteri DSM 17938
Infant colic is a common condition characterized by excessive crying. The otherwise healthy infant aged less than 3 months is difficult to console during the periods with crying.
- Trial name
- NCT02574065
- Testing
- L. reuteri DSM 17938
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Shanghai Children's Hospital
Pain Management, Newborn Pain
Nonpharmacological Methods in Heel Stick Pain
In the present study, the randomized controlled and experimental design is used because it was aimed to determine the effects of two different warming methods (warming with a thermophore heating pad and warming with a warm towel)…
- Trial name
- NCT06847048
- Testing
- Thermophore pad warming group, Warm towel warming group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Diler Yilmaz
Regulation, Self, Reflective Functioning
Recognizing Children's Needs: Impact on Early Childhood Regulatory Problems
Brief Summary: This study aims to quantitatively examine the relationship between regulatory problems (sleep, feeding, and crying) in infants aged 6-36 months and levels of parental sensitivity and reflective functioning.
- Conditions
- Regulation, Self, Reflective Functioning, Mentalization, Child Sleep
- Trial name
- NCT07249593
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Marmara University
Newborn, Neonatal Screening
Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking
The management of the pain is a constant care concern in neonatal and maternity units. Many studies show an interest in the use of sugar solutions to reduce nociception during painful events in infants.
- Trial name
- BBSUCROSE (NCT02374281)
- Testing
- Glucose sucking, Water sucking, No sucking
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infantile Colic
Effects of Vivatlac Baby on Crying Behavior of Colicky Babies
Open trial with two parallel arms, assessing the effects of Simethicone and Vivatlac Baby in babies diagnosed for infantile colic.
- Trial name
- NCT04487834
- Testing
- Simethicone Solution, Vivatlac Baby
- Where
- 2 sites in Poland
- Volunteers
- 87 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
Colic, Inflammation
Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Colic
This study will compare 2 currently marketed formulas in healthy full term babies: Nutramigen A+ (a hypoallergenic formula) and Nutramigen-Enflora (hypoallergenic formula with Lactobacillus GG (LGG)) during 3 months of formula…
- Trial name
- LGG (NCT01279265)
- Testing
- Nutramigen with Enflora, Nutramigen A+
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Preterm Birth
PremCry Study : Study of Ontogeny of Crying in Preterm Infants.
Crying is a survival mechanism for babies and their almost exclusive means of expression until the age of 4 months. Babies 'cry is mostly related to pain, a feeling of hunger, discomfort or separation following the departure of a…
- Trial name
- PremCry (NCT04522414)
- Testing
- cries longitudinally registered
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne