Clinical trials: Cross Infection
Microbial Colonization, Ventilator Associated Pneumonia
Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit
Premature very low birth weight (VLBW) infants are susceptible to complications related to infrequent and non-standardized oral care.
- Trial name
- NCT05167318
- Testing
- frequent standardized oral care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Florida
JOB's Syndrome, Hyper-IgE Recurrent Infection Syndrome
Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome
This study will examine the safety and effectiveness of ranitidine (Zantac) in patients with Hyper-IgE recurrent infection syndrome, a disease characterized by recurrent infections of the ears, sinuses, lungs and skin, and…
- Conditions
- JOB's Syndrome, Hyper-IgE Recurrent Infection Syndrome, Immune Deficiency
- Trial name
- NCT00527878
- Testing
- Ranitidine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ventilator Associated Pneumonia, Nosocomial Pneumonia
Oral Hygiene With Chlorhexidine and Incidence of Ventilator-Associated Pneumonia in Children Submitted to Heart Surgery
Hospital infections play an important role in the increase of patients' morbimortality and hospitalization costs, especially in the case of individuals admitted to intensive care units (ICU) during postoperative heart surgery.
- Conditions
- Ventilator Associated Pneumonia, Nosocomial Pneumonia, Heart Surgery
- Trial name
- NCT00829842
- Testing
- oral hygiene
- Volunteers
- 160 people
- Sponsor
- University of Sao Paulo
Polymyxin B, Ventilator-associated Pneumonia
Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients
The goal of this observational study is to investigate whether intravenous polymyxin B combined with nebulisation achieves better antimicrobial efficacy and clinical outcomes than intravenous use alone in patients with…
- Conditions
- Polymyxin B, Ventilator-associated Pneumonia, Multidrug Resistant Bacterial Infection, Pharmacogenomic Drug Interaction
- Trial name
- NCT06076603
- Testing
- nebulized polymyxin B
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Southeast University, China
Ventilator Associated Pneumonia
Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation.
- Trial name
- VAMPAIR (NCT06554327)
- Testing
- Multiplex PCR
- Where
- France
- Volunteers
- 265 people
- Sponsor
- CHU de Reims
Ventilator-associated Pneumonia
Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates
The goal of this pilot study is to test the hypothesis that mechanically ventilated infants receiving Biotene OralBalance® gel for oral care would have a reduced intubation time compared to infants receiving oral care placebo.
- Trial name
- NCT01314742
- Testing
- Biotene OralBalance® gel, Sterile Water moisten cotton tipped applicator
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Wake Forest University Health Sciences
Ventilator-Associated Pneumonia
Mobile-Based Microlearning for Improving ICU Nurses' Adherence to Ventilator-Associated Pneumonia Prevention Protocols
Ventilator-associated pneumonia (VAP) is one of the most common healthcare-associated infections among mechanically ventilated patients and is associated with increased morbidity, mortality, length of intensive care unit stay…
- Trial name
- VAP-ML (NCT07866027)
- Testing
- Mobile-Based Microlearning Program, Routine Education
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Ventilator-associated Pneumonia
CDC Prevention Epicenters Wake Up and Breathe Collaborative
Ventilator-associated pneumonia (VAP) is a common complication of mechanical ventilation associated with significant morbidity, including prolongation of mechanical ventilation and increased ICU and hospital length-of-stay.
- Trial name
- NCT01583413
- Testing
- Daily SAT & SBT
- Where
- 5 sites in United States
- Volunteers
- 3,342 people
- Sponsor
- Harvard Pilgrim Health Care
Nosocomial Infection, External Causes of Morbidity and Mortality
Tight Glycaemic Control During Cardiac Surgery
To determine whether intraoperative tight glycaemic control can reduce postoperative infection, morbidity and mortality
- Conditions
- Nosocomial Infection, External Causes of Morbidity and Mortality, Hypoglycemia
- Trial name
- TGC (NCT01225159)
- Testing
- TGC, Conventional glycaemic control
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Prince of Songkla University
Pneumonia, Bacterial, Ventilator Associated Pneumonia
MASTERMIND-Pneumonia Study (Also Known as Pneumonia Direct Pilot)
The MASTERMIND-Pneumonia Study (also known as Pneumonia Direct Pilot Study) is designed to assess whether combining molecular diagnostics for bacteria and AMR markers with host-response profiling improves agreement and predictive…
- Trial name
- PDP (NCT06181669)
- Testing
- Pathogen and Host Directed testing
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Duke University
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Ventilator Associated Pneumonia
Perpetual Observational Study - Ventilator Associated Pneumonia
Ventilator-Associated Pneumonia (VAP) is a bacterial respiratory infection that patients in the Intensive Care Unit (ICU) often get when they cannot breathe for themselves and require mechanical ventilation.
- Trial name
- POS-VAP (NCT05719259)
- Where
- 35 sites in Albania, Belgium and 11 more
- Volunteers
- 20,000 people
- Sponsor
- European Clinical Research Alliance for Infectious Diseases (ECRAID)
Ventilator Associated Pneumonia
Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
This study seeks to assess whether coma patients really benefit from the use of antibiotics as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this population group.
- Trial name
- NAVPRO (NCT01118403)
- Testing
- Sultamicillin
- Where
- Colombia
- Sponsor
- Hospital Pablo Tobón Uribe
Ventilator-associated Pneumonia, Hospital-acquired Pneumonia
Identifying Risk Factors for Gram-negative Resistance for HAP/VAP in the Intensive Care Unit
Single center, retrospective chart review. Patients admitted to MDMC ICU from 4/1/2017 to 6/30/2020 will be identified through the electronic medical record utilizing ICD codes for HAP and VAP.
- Trial name
- NCT04700202
- Testing
- Observational
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Methodist Health System
COVID-19, SARS-CoV 2
EXercise TRAining and Sedentary Lifestyle on Clinical Outcomes in Patients With COVID-19
The present study aims to assess the impact of exercise training, physical activity, and sedentary lifestyle on clinical outcomes in surviving patients infected with the severe acute respiratory syndrome coronavirus 2…
- Conditions
- COVID-19, SARS-CoV 2, Corona Virus Infection, Sedentary Behavior
- Trial name
- WHO (NCT04396353)
- Testing
- Electronic questionnaire
- Where
- Brazil
- Volunteers
- 1,574 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Tuberculosis
A Blinded, Cross-sectional, Diagnostic Evaluation Study Performed in Pulmonary TB Suspects at the TB Dispensary for Sector 4 of the Marius-Nasta-Institute in Bucharest, Romania
The diagnosis of tuberculosis (TB) and especially the detection of drug resistance of tuberculosis mycobacteria can be time consuming and costly.
- Trial name
- NCT02382107
- Testing
- Observational
- Where
- Romania
- Volunteers
- 400 people
- Sponsor
- Michael Hoelscher
Hospital-acquired Pneumonia
Efficacy and Safety of Colistimethate Sodium Injection Vial to Treat Hospital-acquired Pneumonia in Adults
1. To evaluate the clinical and microbiological efficacy and safety of Colistimethate sodium Injection Vial to treat adults with hospital-acquired pneumonia . 2.
- Trial name
- NCT01940731
- Testing
- Colistimethate sodium
- Where
- 5 sites in China
- Volunteers
- 60 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
VAP - Ventilator Associated Pneumonia, Care
Effect of the Aspiration Care Bundle on Preventing VAP
Many pharmacological and non-pharmacological interventions are used to prevent ventilator-associated pneumonia (VAP). Nurses are directly responsible for implementing non-pharmacological interventions and therefore have an…
- Conditions
- VAP - Ventilator Associated Pneumonia, Care, Bundle Care, Aspiration
- Trial name
- NCT07138651
- Testing
- Aspiration care bundle
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
COVID-19
Correlation Study of Isotype Switching and Neutralizing Capacity to the COVID-19 Variants Strain
The level of neutralizing antibody was detected by using the constructed pseudovirus covid-19 variant at baseline , 1 month , 6 months and 12 months after primary vaccination, within 15 days after booster immunization at 12…
- Trial name
- NCT05087277
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Ventilator Associated Pneumonia
Study of Different Etiologic Diagnostic Methods in Ventilator Associated Pneumonia (VAP)
The study is designed to evaluate sensitivity, specificity and accuracy of non-bronchoscopic bronchoalveolar lavage and endotracheal aspirate in comparison with bronchoscopic bronchoalveolar lavage (gold standard), as methods for…
- Trial name
- NCT02363023
- Testing
- Collect tracheal and pulmonary secretions
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Uberlandia
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