Clinical trials: Cost Benefit Analysis
Respiratory Tract Infections
Point-of-care Testing of Respiratory Pathogens at Pediatric Emergency Room
The main objective of the trial is to evaluate the effect of point-of-care testing of respiratory pathogens at a pediatric emergency room on the antibiotic consumption and hospital admissions in acutely ill children.
- Trial name
- Hevi-RCT (NCT03932942)
- Testing
- QIAstat at pediatric emergency room
- Where
- Finland
- Volunteers
- 1,350 people
- Sponsor
- University of Oulu
Interdisciplinary Communication, Postoperative Complications
Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients.
- Conditions
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, Operative
- Trial name
- PREPARATION (NCT05703230)
- Testing
- Structured preoperative multidisciplinary team meeting
- Where
- 14 sites in Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Rijnstate Hospital
Lymphoma, Non-Hodgkin, Granulocyte Colony-Stimulating Factor
Cost-Effectiveness Study of PEG-rhG-CSF in Prophylactic Treatment of Neutropenia After Chemotherapy in Lymphoma
This is a pharmacoeconomic research to explore the cost-effectiveness of PEG-rhG-CSF and rhG-CSF in prophylactic treatment of neutropenia in lymphoma patients. It should provide more scientific basis for clinical decision-making.
- Conditions
- Lymphoma, Non-Hodgkin, Granulocyte Colony-Stimulating Factor, Cost-Benefit Analysis
- Trial name
- NCT04083079
- Testing
- PEG-rhG-CSF, rhG-CSF
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Ruijin Hospital
HIV
Gathering Records to Evaluate Antiretroviral Treatment-Malawi ( GREAT )
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04158895)
- Testing
- Routine medical record data collection
- Where
- Malawi
- Volunteers
- 1,000,000 people
- Sponsor
- Boston University
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Cost-effectiveness Analysis, Chronic Kidney Disease Requiring Chronic Dialysis
Cost-effectiveness of Urgent-start Therapies Hemodialysis and Peritoneal Dialysis
This study will evaluate the cost-effectiveness of unplanned dialysis (peritoneal dialysis and hemodialysis) in chronic kidney disease (CKD) during the first year of therapy in a single center.
- Trial name
- NCT03474367
- Where
- Brazil
- Volunteers
- 198 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Depression, Cost Benefit Analysis
Dysthymia: Associated Costs, Treatment and Change Process
The study evaluates cost and effect of inpatient versus outpatient treatment of dysthymia, as well as investigates the processes through which psychotherapy works in treating dysthymia.
- Conditions
- Depression, Cost Benefit Analysis, Psychotherapeutic Processes
- Trial name
- DFront (NCT04911829)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Modum Bad
Malnutrition
Cost-effectiveness Study of the New Nutrition Screening Tool CIPA at Hospital Admission
Objectives: To evaluate the cost-effectiveness of implementing a malnutrition screening tool "CIPA" at the Hospital Universitario Nuestra Señora de la Candelaria (HUNSC), comparing the impact on health and the healthcare costs of…
- Trial name
- NCT02721706
- Testing
- CIPA nutritional screening tool
- Where
- Spain
- Volunteers
- 823 people
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Hip Fractures
Geriatric Fracture Centers - Evaluation of a Geriatric Co-management Program
The study will assess patients with at least one major AE related to treatment / hospitalization / immobilization in the Geriatric Fracture Center (GFC) group compared to the usual care group.
- Trial name
- NCT02297581
- Where
- 12 sites in United States, Austria and 4 more
- Volunteers
- 282 people
- Sponsor
- AO Innovation Translation Center
Influenza Vaccine, Cost-Benefit Analysis
Cost-consequence Analysis of Influenza Vaccination in a Teaching Hospital in Rome
Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity.
- Trial name
- NCT06304038
- Testing
- Flu Vaccine
- Where
- Italy
- Volunteers
- 5,483 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ambulatory Care Information Systems, Clinical Decision Support Systems
Improving Safety and Quality With Outpatient Order Entry
The purpose of this study is to evaluate the impact of integrating ambulatory computerized physician order entry (ACPOE) and advanced clinical decision support systems (CDSS) on safety and quality domains in the ambulatory…
- Trial name
- NCT00243334
- Testing
- Integration of advanced clinical decision support with ambulatory computerized physician order entry
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Brigham and Women's Hospital
Ultrasound-guided Internal Jugular Cannulation, Central Venous Access Complications
Comparison of Three Techniques for Ultrasound-guided Internal Jugular Cannulation
The purpose of this study is to assess the efficacy and safety of three ultrasound assistance techniques for internal jugular venous cannulation, in terms of cannulation success and prevention of complications.
- Trial name
- OISO-1 (NCT01966354)
- Testing
- Ultrasound-guided Internal jugular venous approach
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Mikel Batllori
Heart Failure, Ventricular Dysfunction, Left
ECG Low Ejection Fraction Detection and Guiding in AI Navigated Treatment Era
Asymptomatic left ventricular systolic dysfunction (ALVSD), identified as a key component of stage B heart failure (HF) by AHA/ACC guidelines, is a common precursor to clinically overt HF.
- Conditions
- Heart Failure, Ventricular Dysfunction, Left, Artificial Intelligence, Early Diagnosis
- Trial name
- ELEGANT (NCT06968533)
- Testing
- AI-ECG guided diagnosis
- Where
- Taiwan
- Volunteers
- 13,350 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Competencies of Midwives, Cost-benefit Analysis of Modular Training
Effect of Skill Birth Attendant Training to Improve the Competency of Service Providers
This clinical trial's primary goal is to compare birth attendants' competencies. It aims to answer the questions: Does the new modular training package enhance the competencies of skilled birth attendants? Does the competencies…
- Trial name
- NCT05866016
- Testing
- Skill birth attendant training
- Where
- 2 sites in Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ministry of Health Gandaki Province, Nepal
Obesity, Obese
Cost-effectiveness Study of a Multidisciplinary Weight Loss Method to Improve the Health Condition of Obese Patients
Prospective, observational, multicenter study based on a registry of patients with obesity and associated comorbidities undergoing a standardized multidisciplinary weight loss method with a 2-year follow-up.
- Trial name
- PRONOCOST (NCT05833464)
- Where
- Argentina
- Sponsor
- Protein Supplies SL
Diabetes Mellitus, Hyperglycemia
Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study
The purpose of this study is to compare ways of giving advice and providing support to improve diet and physical activity in adult primary care patients with elevated body mass index and dysglycemia.
- Conditions
- Diabetes Mellitus, Hyperglycemia, Obesity, Glucose Metabolism Disorders
- Trial name
- I-D-HEALTH (NCT01435603)
- Testing
- Standard Lifestyle Advice, Advice Plus Lifestyle Intervention
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Northwestern University
Accidental Falls, Health Behavior
Kuopio Fall Prevention Study.
This study evaluates the 6 month exercise intervention (Taiji and gym course) combined with free use of communal recreation facilities in fall prevention.
- Conditions
- Accidental Falls, Health Behavior, Aging
- Trial name
- KFPS (NCT02665169)
- Testing
- Supervised physical exercise, Health counselling
- Where
- Finland
- Volunteers
- 914 people
- Sponsor
- Kuopio University Hospital
Emotional Disorder, Depression
Cost-benefit Evaluation of a Transdiagnostic Psychological Treatment for Emotional Disorders in Primary Care
The aim of this study is to compare, in cost-effectiveness and cost-utility terms, a brief transdiagnostic cognitive-behavioural therapy in two different modes, individual and group, with the treatment usually administered in…
- Conditions
- Emotional Disorder, Depression, Somatoform Disorders, Anxiety Disorders
- Trial name
- PsicAP-Costs (NCT04847310)
- Testing
- Group brief transdiagnostic cognitive-behavioral therapy, Individual brief transdiagnostic cognitive-behavioral therapy, Treatment as usual
- Where
- 3 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Universidad de Córdoba
Comorbidities and Coexisting Conditions, Ethics
eCardiacRehab - a Hybrid Patient-Centered eHealth Programme
The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy…
- Conditions
- Comorbidities and Coexisting Conditions, Ethics, Continuity of Patient Care, Older Adults (65 Years and Older)
- Trial name
- eCardiacRehab (NCT07590635)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital
Heart Failure
SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.
- Trial name
- SAFE-HOME (NCT03156686)
- Testing
- HOME-based hospitalization
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- French Cardiology Society