Interdisciplinary CommunicationPREPARATIONNCT05703230
Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients
A study testing Structured preoperative multidisciplinary team meeting in people with Interdisciplinary Communication and Postoperative Complications, run by Rijnstate Hospital at 14 sites in Netherlands.
Trial summary
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery
- What is being tested?
- Structured preoperative multidisciplinary team meeting
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,200 participants
- Where
- 14 sitesNetherlands
- Study dates
- 1 Nov 2022to Feb 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 18 years of age or older; and
- American Society of Anesthesiology Physical Status (ASA-PS) score is 3 or more; and
- Clinical Frailty Scale score is 4 or more; and
- Patient is planned for elective or semi-elective noncardiac surgery; and
- As stated by the Dutch perioperative guideline:
- Doubt by the surgeon or anesthesiologist (or other discipline) regarding harm-benefit ratio of the surgical procedure; or
- Doubt if the correct measures were taken to limit the perioperative risk as much as possible; or
- Doubt if the patient agrees with the surgery or the anesthesiologic treatment and expected risks.
Who cannot join
- no informed consent
- unable to communicate with patient (either directly or through third party)
- emergency surgery
- Proposed surgical intervention for which a structured preoperative multidisciplinary team meeting, similar to the current study intervention, already exists in this respective hospital at the start of the study
Trial locations and contacts
14 sites in 1 country.
14 sites in 1 country
Netherlands14 sites
Stichting Jeroen Bosch Ziekenhuis
's-Hertogenbosch, 5223GZ
Stichting Meander Medisch Centrum
Amersfoort, 3817TZ
Stichting OLVG
Amsterdam, 1091
Gelre Ziekenhuis
Apeldoorn, 7334DZ
Stichting Albert Schweitzer Ziekenhuis
Dordrecht, 3318AT
Groene Hart Ziekenhuis
Gouda, 2803HH
Universitair Medisch Centrum Groningen
Groningen, 9713GZ
Zuyderland Medisch Centrum
Heerlen, 6419PC
Maastricht Universitair Medisch Centrum
Maastricht, 6229HX
Stichting Nijmeegs Interconfessioneel Ziekenhuis Canisius Wilhelmina
Nijmegen, 6532SZ
Stichting Bravis Ziekenhuis
Roosendaal, 4708AE
Stichting Protestants Christelijk Ziekenhuis Ikazia
Rotterdam, 3083AN
Maxima Medisch Centrum
Veldhoven, 5504DB
Zaans Medisch Centrum
Zaandam, 1502DV
About this study
Official title: Is a Preoperative Multidisciplinary Team Meeting (Cost) Effective in Optimizing Noncardiac Surgical Patient Management: The PREPARATION Study
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients.
The main questions to answer are:
Read more
- Primary question: Does implementation of preoperative multidisciplinary team discussions for high risk noncardiac surgical patients diminish serious adverse events as compared to care as usual at six months postoperatively or six months after multidisciplinary team discussion in case of nonsurgical treatment?
- Secondary questions: Does implementation of preoperative multidisciplinary team discussion for high risk noncardiac surgical patients improve disability, survival, functional outcome, quality of life and cost-effectiveness as compared to care as usual at six months postoperatively or six months after multidisciplinary team discussion in case of nonsurgical treatment?
Participants will be asked to answer questionnaires at baseline, 3, 6,9 and 12 months postoperatively or post MDT discussion.
Patients for whom no structured preoperative multidisciplinary discussion is installed yet (care as usual) will be compared with patients for whom a structured preoperative multidisciplinary discussion is performed (intervention).
The study will be performed in hospitals that have no established preoperative MDT meeting at the start of the study.
Read the detailed description
Due to the increase in life expectancy and improved care for patients suffering from a chronic disease, the number of complex patients requiring a surgical intervention is increasing. It is important to balance the potential benefits of this surgical treatment against the risk of permanent loss of functional capacity and quality of life due to complications. European and US guidelines on perioperative care all recommend preoperative multidisciplinary team meetings for high-risk noncardiac surgical patients. However, the evidence underlying a benefit of a preoperative MDT meeting is absent and recommendations are based on expert opinion. Moreover, considerable practice variation is currently present.
This study will assess the efficacy of implementation of a preoperative structured multidisciplinary team (sMDT) meeting to optimize perioperative management for high risk noncardiac surgical patients.
The hypothesis is that implementation of preoperative sMDT meetings for high risk noncardiac surgical patients results in less serious adverse events, is more cost-effective, and improves quality of life and functional outcome at six months, compared to preoperative care as usual (control).
A preoperative structured Multidisciplinary Team (sMDT) meeting for high risk noncardiac surgical patients will be implemented in each participating center (n=14) throughout the study. In the sMDT meeting, patients' treatment plan and alternatives will be discussed by the anesthesiologist, surgical specialist and other relevant consultants or (specialized) nurses.
The primary outcome is Serious adverse events (SAEs) according to the Clavien Dindo classification grade 3 or more, at 6 months following surgery or following the preoperative sMDT meeting in case of nonsurgical management. Secondary outcomes are: functional outcome (12-item WHO Disability Assessment Schedule), survival, quality of life (WHOQOL BREF), patients' regret (including interview at 6 months), societal costs (iMCQ and iPCQ, Electronic Medical Record (EMR) data, EQ5D-5L), alterations in perioperative management and sMDT performance (MDT-MOT), and facilitators and barriers (using structured interviews health care professionals). Most secondary outcomes will be assessed at baseline, 30 days, 3, 6 and 12 months.
Subgroup analyses will take place for e.g. age groups (approximate quintiles), patient sex, size of hospital, intent of surgery, BMI categories (underweight, normal, overweight, obese, ≥super obese), ASA physical status, frailty, MET score, smoking behavior, alcohol use, comorbidity index score, planned postoperative destination, educational attainment, and employment status.
For detailed description, see below.
- Conditions
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, Operative, Preoperative Care, Patient Care Team
- Being tested
- Structured preoperative multidisciplinary team meeting
- Keywords
- multidisciplinary team meeting, preoperative, high risk surgical patients
- Medical subject headings
- Postoperative Complications
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Structured preoperative multidisciplinary team meetingOther
The intervention to be investigated is the introduction of a preoperative structured multidisciplinary team (sMDT) meeting for high risk noncardiac surgical patients, which is attended by at least the treating surgical specialist, an anesthesiologist and another medical consultant with expertise relevant for the patients comorbidities and preferences. In the preoperative sMDT meeting, at least the following questions will be discussed as recommended by the Dutch Perioperative Guideline:
- Is the proposed surgical intervention appropriate care for the patient?
- Is the risk/benefit ratio of the proposed surgical intervention acceptable for the patient?
- Should the patient's condition be optimized before undergoing the proposed surgical intervention?
| Study group | Role | What they receive |
|---|---|---|
| Preoperative care as usual | No intervention | Patients undergoing preoperative care as usual, which does not include a structured preoperative multidisciplinary team meeting (no sMDT meeting) |
| Structured preoperative multidisciplinary team meeting | Active comparator | Patients are discussed preoperatively in a structured preoperative multidisciplinary team meeting Receives: Other: Structured preoperative multidisciplinary team meeting |
What is being measured
The primary outcome is the main question the study is designed to answer.
Serious Adverse Events (SAEs)
Serious adverse events (SAEs), defined as:
- Grade 3 or more on the Clavien Dindo classification following surgical intervention, or
- non-operative SAEs will be graded accordingly i.e., events necessitating hospital admission, surgical intervention, single or multi-organ failure, or death.
Measured: 6 months
Secondary outcomes (20)
Disability status
The disability status of the patient, measured by the 12-item WHO disability Assessment Schedule 2.0 (WHODAS 2.0). The WHODAS 2.0 results in a metric ranging from 0 to 100 ( where 0 = no disability; 100 = full disability).
Measured: 12 months
Patient experienced quality of life
Quality of life of the patient assessed by the abbreviated World Health Organization Quality of Life (WHOQOL BREF). The WHOQOL BREF results in a percentage of 0 to 100. The higher the percentage (to 100), the better the quality of life of the participant.
Measured: 12 months
Regret of decision
Patients regret of decision measured by a modification of the Decision Regret Scale at 3, 6 and 12 months and qualitative interviews with several patients at 6 months.
The decision regret scale is a 5-item questionnaire, scoring statements 1 (strongly agree) to 5 (strongly disagree). Final scoring consists of reversing the scores of the two negatively phrased items, then taking the mean of the five items. Last, the mean is converted to a score ranging from 0 to 100 by subtracting 1 and multiplying by 25. A higher score may indicate greater patient regret about their made treatment decisions. The scale was modified by adding a question asking by whom the decision was made. This question is not part of the previously described scoring of the 5-item decision regret scale.
Measured: 12 months
Societal costs measured by a patient cost questionnaire
Societal costs as measured by a cost questionnaire at baseline, 3 and 12 months, including items of the iMTA (Institute for Medical Technology Assessment) Medical Consumption Questionnaire (iMCQ) and iMTA Productivity Cost Questionnaire (iPCQ) with a recall period of 3 months.
Measured: 12 months
Hospital costs as a component of societal costs
Hospital costs based on electronic medical record (EMR) patient data, as a component of societal costs. Measured at baseline (hospital costs over a period of 3 months prior to preoperative screening) and measured during 12 months follow up.
Measured: 12 months
Quality-adjusted life years as a component of societal costs
Quality-adjusted life years (QALYs) measured by the EQ-5D-5L at baseline, 3 and 12 months, as a component of societal costs.
Measured: 12 months
Patients' desired outcome
Patients' desired outcome will be assessed using the Outcome Prioritization Tool (OPT) at baseline (pre-operative assessment).
Measured: baseline
Survival
Survival at 30 days, 6 months, and 1 year postoperatively
Measured: 30 days, 6 months, and 1 year postoperatively
Adverse events
Adverse events at 30 days, 6 months, and 1 year postoperatively
Measured: 30 days, 6 months, and 1 year postoperatively
Surgical Outcome Risk Tool (SORT)
Calculating an estimate of the patients' risk of death within 30 days of an operation.
Measured: baseline
Revised Cardiac Risk Index for Pre-Operative Risk (RCRI)
The RCRI estimates patients' risk of cardiac complications after noncardiac surgery. The index is constructed by 6 items. The 6 items are scored yes (+1) or no (0), adding up to a minimum score of 0 and a maximum score of 6. The score is categorised into 4 categories (0, 1, 2, ≥3) and converted to "risk of major cardiac event (95% CI)" defined as death, myocardial infarction, or cardiac arrest at 30 days after noncardiac surgery.
Measured: baseline
American College of Surgeons Surgical Risk Calculator (ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Program))
Estimates patients' risk of postoperative complications.
Measured: baseline
Clinical Frailty Scale (CFS)
A judgement-based frailty tool that evaluates specific domains including comorbidity, function, and cognition to generate a frailty score ranging from 1 (very fit) to 9 (terminally ill).
Measured: baseline
Metabolic Equivalent of Task (MET)
Reflecting the amount of energy used by the body during physical activity.
Measured: baseline
The number of alterations in perioperative management decided by the sMDT.
The number of alterations in perioperative management decided by the sMDT (19, 20). Examples for alterations are (but not limited to) changes in; type of anaesthesia, type of surgery, planned postoperative intensive care admission, cancellation of surgery, additional medication or diagnostics.
Measured: baseline
The nature of alterations in perioperative management decided by the sMDT.
The nature of alterations in perioperative management decided by the sMDT (19, 20). Examples for alterations are (but not limited to) changes in; type of anaesthesia, type of surgery, planned postoperative intensive care admission, cancellation of surgery, additional medication or diagnostics.
Measured: baseline
The number of different medical specialties invited to participate in the sMDT meeting
The number of different medical specialties present during the sMDT meeting in order to describe the multidisciplinary attendance of the sMDT meetings.
Measured: baseline
The number of different medical specialties present during the sMDT meeting
The number of different medical specialties present during the sMDT meeting in order to describe the multidisciplinary attendance of the sMDT meetings.
Measured: baseline
The function of attending professionals at the sMDT meeting.
The function of attending professionals at the sMDT meeting in order to describe the multidisciplinary attendance of the sMDT meetings.
Measured: baseline
Number of sMDT discussions per site
Number of sMDT discussions per site
Measured: through study completion, 3 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2023
- Study start1 Nov 2022
- Primary completion31 Dec 2026 (estimated)
- Study completionFeb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Interdisciplinary CommunicationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Sequential
- Model description
- cross-sectional stepped wedge cluster randomized trial
- Masking
- None (open label)
- Enrolment
- 1,200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Rijnstate Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, University of Twente, University Medical Center Groningen, Maastricht University Medical Center, Leiden University Medical Center
- Responsible party
- Sponsor
- Investigators
- Nick J. Koning, MD PhD DESA, Principal investigator, Rijnstate HospitalJacqueline E. Vernooij, MD, MA, Study director, Rijnstate Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05703230
- Sponsor's protocol ID
- 2021-1983
- Acronym
- PREPARATION
- Status last verified
- Feb 2026
- First submitted
- 4 Nov 2022
- Last updated
- 25 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data will be made accessible on request after agreement has been received from the entire project group. The principal investigator will communicate data availability with researchers sending the requests.
Publications
Vernooij JEM, Boerlage RM, Doggen CJM, Preckel B, Dirksen CD, van Leeuwen BL, Spruit RJ, Festen S, van der Wal-Huisman H, van Basten JP, Kalkman CJ, Koning NJ; PREPARATION study investigators. Is a preoperative multidisciplinary team meeting (cost)effective to improve outcome for high-risk adult patients undergoing noncardiac surgery: the PREPARATION study-a multicenter stepped-wedge cluster randomized trial. Trials. 2023 Oct 11;24(1):660. doi: 10.1186/s13063-023-07685-3.
PubMed 37821994Vernooij JEM, Hobrink E, Boerlage RM, van Beest P, van de Calseijde S, Holl T, Janssen LMJ, Klinkert L, Marsman M, Nouwen MJ, Wefers Bettink MA, Preckel B, Kalkman CJ, van Leeuwen B, Festen S, Koning NJ. Characteristics and outcome of preoperative multidisciplinary team discussions for high-risk noncardiac surgical patients in the Netherlands: a multicentre prospective observational study. Br J Anaesth. 2025 Aug;135(2):449-458. doi: 10.1016/j.bja.2025.05.004. Epub 2025 Jun 6.
PubMed 40480911
Study at a glance
From the registry record, last updated by the sponsor on 25 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Is a Preoperative Multidisciplinary Team Meeting (Cost) Effective in Optimizing Noncardiac Surgical Patient Management: The PREPARATION Study
- ClinicalTrials.gov ID
- NCT05703230
- Acronym / sponsor ID
- PREPARATION / 2021-1983
- Conditions
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, Operative, Preoperative Care, Patient Care Team
- Keywords
- multidisciplinary team meeting, preoperative, high risk surgical patients
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 1,200 participants (estimated)
- Lead sponsor
- Rijnstate HospitalUniversity, hospital or other
- Collaborators
- ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, University of Twente, University Medical Center Groningen, Maastricht University Medical Center, Leiden University Medical Center
- Study start
- 1 Nov 2022 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- Feb 2027 (estimated)
- First posted
- 27 Jan 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients.
The main questions to answer are:
- Primary question: Does implementation of preoperative multidisciplinary team discussions for high risk noncardiac surgical patients diminish serious adverse events as compared to care as usual at six months postoperatively or six months after multidisciplinary team discussion in case of nonsurgical treatment?
- Secondary questions: Does implementation of preoperative multidisciplinary team discussion for high risk noncardiac surgical patients improve disability, survival, functional outcome, quality of life and cost-effectiveness as compared to care as usual at six months postoperatively or six months after multidisciplinary team discussion in case of nonsurgical treatment?
Participants will be asked to answer questionnaires at baseline, 3, 6,9 and 12 months postoperatively or post MDT discussion.
Patients for whom no structured preoperative multidisciplinary discussion is installed yet (care as usual) will be compared with patients for whom a structured preoperative multidisciplinary discussion is performed (intervention).
The study will be performed in hospitals that have no established preoperative MDT meeting at the start of the study.
Detailed description
Due to the increase in life expectancy and improved care for patients suffering from a chronic disease, the number of complex patients requiring a surgical intervention is increasing. It is important to balance the potential benefits of this surgical treatment against the risk of permanent loss of functional capacity and quality of life due to complications. European and US guidelines on perioperative care all recommend preoperative multidisciplinary team meetings for high-risk noncardiac surgical patients. However, the evidence underlying a benefit of a preoperative MDT meeting is absent and recommendations are based on expert opinion. Moreover, considerable practice variation is currently present.
This study will assess the efficacy of implementation of a preoperative structured multidisciplinary team (sMDT) meeting to optimize perioperative management for high risk noncardiac surgical patients.
The hypothesis is that implementation of preoperative sMDT meetings for high risk noncardiac surgical patients results in less serious adverse events, is more cost-effective, and improves quality of life and functional outcome at six months, compared to preoperative care as usual (control).
A preoperative structured Multidisciplinary Team (sMDT) meeting for high risk noncardiac surgical patients will be implemented in each participating center (n=14) throughout the study. In the sMDT meeting, patients' treatment plan and alternatives will be discussed by the anesthesiologist, surgical specialist and other relevant consultants or (specialized) nurses.
The primary outcome is Serious adverse events (SAEs) according to the Clavien Dindo classification grade 3 or more, at 6 months following surgery or following the preoperative sMDT meeting in case of nonsurgical management. Secondary outcomes are: functional outcome (12-item WHO Disability Assessment Schedule), survival, quality of life (WHOQOL BREF), patients' regret (including interview at 6 months), societal costs (iMCQ and iPCQ, Electronic Medical Record (EMR) data, EQ5D-5L), alterations in perioperative management and sMDT performance (MDT-MOT), and facilitators and barriers (using structured interviews health care professionals). Most secondary outcomes will be assessed at baseline, 30 days, 3, 6 and 12 months.
Subgroup analyses will take place for e.g. age groups (approximate quintiles), patient sex, size of hospital, intent of surgery, BMI categories (underweight, normal, overweight, obese, ≥super obese), ASA physical status, frailty, MET score, smoking behavior, alcohol use, comorbidity index score, planned postoperative destination, educational attainment, and employment status.
For detailed description, see below.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Sequential
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- cross-sectional stepped wedge cluster randomized trial
| Arm | Type | Receives |
|---|---|---|
| Preoperative care as usual | No intervention | –Patients undergoing preoperative care as usual, which does not include a structured preoperative multidisciplinary team meeting (no sMDT meeting) |
| Structured preoperative multidisciplinary team meeting | Active comparator | Other: Structured preoperative multidisciplinary team meetingPatients are discussed preoperatively in a structured preoperative multidisciplinary team meeting |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- 18 years of age or older; and
- American Society of Anesthesiology Physical Status (ASA-PS) score is 3 or more; and
- Clinical Frailty Scale score is 4 or more; and
- Patient is planned for elective or semi-elective noncardiac surgery; and
- As stated by the Dutch perioperative guideline:
Key exclusion criteria (4 listed)
- no informed consent
- unable to communicate with patient (either directly or through third party)
- emergency surgery
- Proposed surgical intervention for which a structured preoperative multidisciplinary team meeting, similar to the current study intervention, already exists in this respective hospital at the start of the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Structured preoperative multidisciplinary team meetingThe intervention to be investigated is the introduction of a preoperative structured multidisciplinary team (sMDT) meeting for high risk noncardiac surgical patients, which is attended by at least the treating surgical specialist, an anesthesiologist and another medical consultant with expertise relevant for the patients comorbidities and preferences. In the preoperative sMDT meeting, at least the following questions will be discussed as recommended by the Dutch Perioperative Guideline: * Is the proposed surgical intervention appropriate care for the patient? * Is the risk/benefit ratio of the proposed surgical intervention acceptable for the patient? * Should the patient's condition be optimized before undergoing the proposed surgical intervention? | Other | Structured preoperative multidisciplinary team meeting |
Primary outcome
Serious Adverse Events (SAEs)
Time frame: 6 months
Serious adverse events (SAEs), defined as: 1. Grade 3 or more on the Clavien Dindo classification following surgical intervention, or 2. non-operative SAEs will be graded accordingly i.e., events necessitating hospital admission, surgical intervention, single or multi-organ failure, or death.
20 secondary outcomes
Disability status
Time frame: 12 months
Patient experienced quality of life
Time frame: 12 months
Regret of decision
Time frame: 12 months
Societal costs measured by a patient cost questionnaire
Time frame: 12 months
Hospital costs as a component of societal costs
Time frame: 12 months
Quality-adjusted life years as a component of societal costs
Time frame: 12 months
Patients' desired outcome
Time frame: baseline
Survival
Time frame: 30 days, 6 months, and 1 year postoperatively
Adverse events
Time frame: 30 days, 6 months, and 1 year postoperatively
Surgical Outcome Risk Tool (SORT)
Time frame: baseline
Revised Cardiac Risk Index for Pre-Operative Risk (RCRI)
Time frame: baseline
American College of Surgeons Surgical Risk Calculator (ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Program))
Time frame: baseline
Clinical Frailty Scale (CFS)
Time frame: baseline
Metabolic Equivalent of Task (MET)
Time frame: baseline
The number of alterations in perioperative management decided by the sMDT.
Time frame: baseline
The nature of alterations in perioperative management decided by the sMDT.
Time frame: baseline
The number of different medical specialties invited to participate in the sMDT meeting
Time frame: baseline
The number of different medical specialties present during the sMDT meeting
Time frame: baseline
The function of attending professionals at the sMDT meeting.
Time frame: baseline
Number of sMDT discussions per site
Time frame: through study completion, 3 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Feb 2026.
- Background: PubMed 37821994Vernooij JEM, Boerlage RM, Doggen CJM, Preckel B, Dirksen CD, van Leeuwen BL, Spruit RJ, Festen S, van der Wal-Huisman H, van Basten JP, Kalkman CJ, Koning NJ; PREPARATION study investigators. Is a preoperative multidisciplinary team meeting (cost)effective to improve outcome for high-risk adult patients undergoing noncardiac surgery: the PREPARATION study-a multicenter stepped-wedge cluster randomized trial. Trials. 2023 Oct 11;24(1):660. doi: 10.1186/s13063-023-07685-3.
- Derived from this study: PubMed 40480911Vernooij JEM, Hobrink E, Boerlage RM, van Beest P, van de Calseijde S, Holl T, Janssen LMJ, Klinkert L, Marsman M, Nouwen MJ, Wefers Bettink MA, Preckel B, Kalkman CJ, van Leeuwen B, Festen S, Koning NJ. Characteristics and outcome of preoperative multidisciplinary team discussions for high-risk noncardiac surgical patients in the Netherlands: a multicentre prospective observational study. Br J Anaesth. 2025 Aug;135(2):449-458. doi: 10.1016/j.bja.2025.05.004. Epub 2025 Jun 6.
- Individual participant dataSharing planned: Yes. Data will be made accessible on request after agreement has been received from the entire project group. The principal investigator will communicate data availability with researchers sending the requests.
Related trials for Interdisciplinary Communication
Recruiting
Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?
Amyotrophic Lateral Sclerosis (ALS)
Active, not recruiting
Better Communication, Better Care Using SICG Assistant Based on Artificial Intelligence
Cancer Care Providers
Recruiting
Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology
Neoplasms, Frailty
Not yet recruitingObservational study
Evaluation of Interactions and Group Processes in Multidisciplinary Tumor Boards in Gynecologic Oncology
Ovarian Neoplasms, Uterine Neoplasms
Recruiting
Speech and Arm Combined Exergame
Cerebral Palsy (CP), Dysarthria
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nick J. Koning, MD PhD DESA principal investigator
Rijnstate Hospital
Jacqueline E. Vernooij, MD, MA study director
Rijnstate Hospital
14 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Structured preoperative multidisciplinary team meeting in people with Interdisciplinary Communication and Postoperative Complications, run by Rijnstate Hospital at 14 sites in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 25 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 14 sites in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Serious Adverse Events (SAEs) (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05703230, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Feb 2026.