Clinical trials: Contingency Management, active
Advanced Bladder Cancer
The Impact of Time-of-day Administration of EV/P on Objective Response Rate in Adults With Advanced Bladder Cancer
The goal of this clinical trial is to learn if the timing of treatments plays a role in how effective the standard-of-care drugs enfortumab vedotin and pembrolizumab (EV/P) works to treat adults with advanced bladder cancer.
- Trial name
- Chrono-EVP (NCT07346053)
- Testing
- enfortumab vedotin and pembrolizumab (EV/P)
- Where
- 5 sites in Canada
- Volunteers
- 224 people
- Sponsor
- Guliz Ozgun
Opioid Use Disorder
Reentry Incentives and Support for Engagement With Contingency Management
People leaving jail face a very high risk of overdose, especially in the first few weeks after release. Staying on medication for opioid use disorder (MOUD) can greatly reduce this risk, but many people stop treatment during this…
- Trial name
- RISE-CM (NCT07322588)
- Testing
- Reentry Incentives and Support for Engagement with Contingency Management (RISE-CM) Intervention
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Oregon Health and Science University
Gestatiaonl Diabetes Mellitus, Pregnancy
Injection Ports vs Single-Use Needles for Insulin in Pregnancy: Effects on Adherence and Satisfaction
This study wants to find out if using an injection port to give insulin during pregnancy helps people take their insulin more regularly and feel better about their care.
- Conditions
- Gestatiaonl Diabetes Mellitus, Pregnancy, Diabetes in Pregnancy, Insulin Dependent Diabetes Mellitus
- Trial name
- NCT07165327
- Testing
- Injection Port for Insulin Administration, Single-Use Insulin Needles
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Texas at Austin
Venous Thromboembolism
Shared Decision-making Process for Unprovoked vEnous THromboEmbolism Management. (ETHER )
Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a frequent disease and the third most common cause of cardiovascular death in the world after myocardial infarction and stroke.
- Trial name
- ETHER (NCT06731244)
- Testing
- Usual Care Group, shared decision-making process
- Where
- 20 sites in France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Brest
Smoking Cessation
Family-Based Financial Incentives Intervention for Smoking Cessation
The current study will conduct an RCT to evaluate the effectiveness of a family-based incentive intervention with Alaska Native/American Indian families.
- Trial name
- Aniqsaaq-RCT (NCT06556433)
- Testing
- Financial Incentive Rewards
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- Mayo Clinic
Cannabis Use Disorder
Rewards for Cannabis Abstinence-study
The goal of this clinical trial is to investigate the (cost-)effectiveness of contingency management (CM) compared with Cognitive Behavioural Therapy (CBT) for the treatment of cannabis use disorder (CUD) in youth (16-22 years).
- Trial name
- RECAB (NCT05836207)
- Testing
- Abstinence-focused Contingency Management (CM) - stand alone, Standard Outpatient Cognitive Behavioural Therapy (CBT)
- Where
- 5 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- Parnassia Addiction Research Centre
Opioid Use Disorder, Opioid Dependence With Current Use (Disorder)
Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement
There is growing recognition of the need for approaches to initiate treatment wherever patients touch the health care system, including the Emergency Department (ED).
- Trial name
- NCT05897788
- Testing
- Text Message Check-ins, Contingency Management
- Where
- United States
- Volunteers
- 1,808 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Opioid Use Disorder (OUD)
Contingency Management for Opioid Use Disorder in Inpatients at Assiut University Hospital
A scientific study to design and implement a contingency management (CM) program, and to evaluate its effectiveness in promoting abstinence and treatment adherence among individuals with opioid use disorder, as well as to explore…
- Trial name
- NCT07208266
- Testing
- contingency management
- Volunteers
- 55 people
- Sponsor
- Assiut University
Diabetes, Type 2 Diabetes (T2DM)
CGM Use in Non-insulin Patients With DM2
The U.S. Food and Drug Administration (FDA) has approved multiple Continuous Glucose Monitoring (CGM) devices from different manufacturers to be used as an aide in patients with type 1 and type 2 diabetes who require medications…
- Conditions
- Diabetes, Type 2 Diabetes (T2DM), Obesity Type 2 Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
- Trial name
- CGM-DWI (NCT07128342)
- Testing
- CGM Group, FSBG group
- Volunteers
- 100 people
- Sponsor
- Milwaukee VA Medical Center
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cocaine Use Disorder (CUD)
Contingency Management Plus Deep Transcranial Magnetic Stimulation for the Treatment of Cocaine Use Disorder
The purpose of this study is to evaluate the effects of Contingency Management (CM)+transcranial magnetic stimulation (TMS) on treatment outcomes in individuals who are initial non-responders and to evaluate the effects of CM+TMS…
- Trial name
- NCT07490600
- Testing
- Contingency Management (CM), Transcranial Magnetic Stimulation (TMS) experimental
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use Disorder, Substance Use Disorder (SUD)
Contingency Management for Veteran Smokers Undergoing Major Elective Surgery
The goal of this study is to design and test the first mobile contingency management (CM) smoking cessation intervention for military Veterans undergoing major elective surgery.
- Trial name
- CM_Surgery (NCT06678672)
- Testing
- Contingency Management (CM), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, San Francisco
MBSR, Young Adults
A Reinforced Mindfulness-Based Intervention to Reduce Problematic Drinking Among Hispanic Emerging Adults
This study is a trial to evaluate a mindfulness program designed for Hispanic young adults. Participants will be randomly assigned to one of two groups: (1) an in-person, 8-week mindfulness program (one 1.5-hour session per week…
- Conditions
- MBSR, Young Adults, Heavy Episodic Drinking
- Trial name
- Mindfulness (NCT07192094)
- Testing
- Mindfulness Sessions - 8 Week Program
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Florida International University
Breast Cancer, Drug-Related Side Effects and Adverse Reactions
Telenursing for the Early Detection and Management of Side Effects Associated With Cyclin-Dependent Kinase Inhibitors in Breast Cancer Patients
This study is a multicenter randomized controlled trial designed to evaluate the effectiveness of a structured telenursing intervention in patients with breast cancer receiving cyclin-dependent kinase (CDK) inhibitor therapy.
- Conditions
- Breast Cancer, Drug-Related Side Effects and Adverse Reactions, Chemotherapy Toxicity, Treatment Adherence
- Trial name
- NCT07524829
- Testing
- Structured Telenursing Follow-up, Standard Nursing Care
- Where
- Italy
- Volunteers
- 124 people
- Sponsor
- Azienda Sanitaria Locale di Asti
HIV Prevention, Sexually Transmitted Infections (STI)
California MEPS Hub
The California Hub for HIV/SUD Prevention Research with Reentry Populations addresses the question: "Can the evidence-based MEPS intervention be adapted and implemented at a range of organizations to effectively serve a wider…
- Conditions
- HIV Prevention, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP), Incarceration
- Trial name
- NCT07433985
- Testing
- Mobile Enhanced Prevention Support (MEPS), Control
- Where
- 3 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gambling Disorder
Contingency Management as an Adjunct Treatment for Rural and Remote Disordered Gamblers
The purpose of this project is to pilot contingency management as an adjunct treatment to counselling as usual using internet delivered video-conferencing applications for remote disordered gamblers.
- Trial name
- NCT02953899
- Testing
- Contingency Management, Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Heart Failure, Heart Diseases
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are…
- Conditions
- Heart Failure, Heart Diseases, Cardiovascular Diseases, Pulmonary Hypertension
- Trial name
- TEAM-HF (NCT06526195)
- Testing
- CardioMEMS HF System, HeartMate 3 Left Ventricular Assist System, Guideline Medical Directed Therapy
- Where
- 70 sites in United States, Austria and 6 more
- Volunteers
- 850 people
- Sponsor
- Abbott Medical Devices
Methamphetamine-Associated Heart Failure, Methamphetamine-Associated Pulmonary Arterial Hypertension
Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
The purpose of this study is to evaluate the feasibility and preliminary effectiveness of increasing control over stimulant use and physical health through incentivized rehabilitation (INSPIRE).
- Trial name
- INSPIRE (NCT07915882)
- Testing
- Increasing control over stimulant use and physical health through incentivized rehabilitation, Usual Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Michael Incze
Acute Respiratory Conditions Requiring Oxygen Therapy, Advanced Practice Nursing
Impact of an Emergency Advanced Practice Nurse on Complications After Home Discharge of Oxygen-Dependent Patients Managed in the Emergency Department: A Quantitative and Qualitative Study
Since the COVID-19 pandemic, discharging patients home on low-flow oxygen therapy has proven to be a safe and effective alternative to hospitalization, helping to relieve overcrowded hospitals while ensuring continuity of care.
- Conditions
- Acute Respiratory Conditions Requiring Oxygen Therapy, Advanced Practice Nursing, Home Care Services, Home Oxygen Therapy
- Trial name
- OXYURG-IPA (NCT07782892)
- Testing
- APN-physician team management of the Oxy-Urg pathway, Usual care: physician-alone management of the Oxy-Urg pathway
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Strasbourg, France
Opioid-use Disorder, HIV Prevention Program
Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services
The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exposure prophylaxis (PrEP) adherence and support services (CoMPASS) to…
- Trial name
- CoMPASS (NCT04738825)
- Testing
- Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
- Where
- 6 sites in United States
- Volunteers
- 526 people
- Sponsor
- Yale University