Clinical trials: Complex Aortic Aneurysms
Aortic Aneurysm, Abdominal, Thoracic Aneurysm
Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
The purpose of this study is to assess the clinical outcomes and radiation of the use of off-the-shelf and custom-made devices (CMDs) for the endovascular repair of juxtarenal, suprarenal, thoracoabdominal and arch aortic…
- Trial name
- NCT02266719
- Testing
- Fenestrated CMD, Type I - III TAAA, Arch cohort
- Where
- 4 sites in United States
- Volunteers
- 750 people
- Sponsor
- Carlos Timaran
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
- Trial name
- NCT02089607
- Testing
- CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
- Where
- 3 sites in United States
- Volunteers
- 760 people
- Sponsor
- Gustavo S Oderich
Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm
Physician Modified Endograft For Complex Aortic Aneurysm Repair
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk…
- Conditions
- Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT05339061
- Testing
- Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Complex Aortic Aneurysms
MOSTEGRA TRIAL:MO-(Dified) STE-(nt) GRA(-ft): Surgeon-modified Fenestrated-branched Stent-grafts
This trial evaluates surgeon-modified fenestrated-branched stent-grafts (sm-FBSG) for Abdominal Aortic Aneurysms (AAA) that are custom-made intra-operatively with no waiting period by a qualified vascular surgeon.
- Trial name
- MOSTEGRA (NCT02101463)
- Testing
- surgeon-modified fenestrated-branched stent-grafts (sm-FBSG)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Northside Hospital, Inc.
Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Grafts (PMEGs)
The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patients.
- Conditions
- Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Dissection
- Trial name
- NCT04746677
- Testing
- Endovascular aortic repair with a physician-modified endovascular graft (PMEG), TREO graft
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Beth Israel Deaconess Medical Center
Juxtarenal Abdominal Aortic Aneurysm
Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT Study)
A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd.
- Trial name
- NCT05179967
- Testing
- WeFlow-JAAA Stent Graft System
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Complex Aortic Aneurysms
Analysis of Respiration-induced Deformations in Visceral and Renal Arteries Before and After Stenting During Branched Stent Treatment.
Aneurysm of the abdominal aorta is defined by a loss of parallelism of the arterial wall. The main risk of this pathology is the rupture of the aneurysm which is life threatening and this risk increases with the size of the…
- Trial name
- BEVAR (NCT04991636)
- Testing
- Angioscan
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Thoracic Aortic Aneurysm
Intravascular Ultrasound (IVUS) in Complex Aortic Endovascular Interventions
The study aims to investigate the applicability of intravascular ultrasound (IVUS) in the endovascular therapy of juxta-, supra- and thoracoabdominal aortic aneurysms.
- Trial name
- NCT04663074
- Testing
- IVUS control
- Where
- 6 sites in Denmark, Germany and 2 more
- Volunteers
- 80 people
- Sponsor
- University Hospital Muenster
Inflammatory Abdominal Aortic Aneurysm, Aneurysm, Infected
Complex EVAR in Inflammatory and Infective Abdominal and Thoracoabdominal Aortic Aneurysms
Complex endovascular aortic repair in inflammatory and infective perivisceral abdominal aortic aneurysms and thoracoabdominal aortic aneurysms (CEVARII) study is a collaborative international effort among vascular surgeons to…
- Conditions
- Inflammatory Abdominal Aortic Aneurysm, Aneurysm, Infected, Aneurysm, Mycotic, Abdominal Aortic Aneurysm
- Trial name
- CEVARII (NCT06380595)
- Testing
- Complex endovascular aortic repair (cEVAR)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- CEVARII
Complex Abdominal Aortic Aneurysm
Compassionate Use Treatment for a Single Patient With a Custom Made Branched/Fenestrated Endovascular Device for the Treatment of Complex Abdominal Aortic Aneurysm
The FENESTRATED AAA ENDOVASCULAR GRAFT WITH THE H\&L-B ONE-SHOT™ INTRODUCTION SYSTEM is neither commercially available or available as part of a clinical trial.
- Trial name
- NCT03159858
- Testing
- Fenerated AAA Endovascular Graft with H&L-B One Shot Introduction System
- Where
- United States
- Sponsor
- NYU Langone Health
Complex Aortic Aneurysms, Thoracoabdominal Aneurysm
Real-World Data Collection of GORE Devices Used In the Endovascular Treatment of Aortic Aneurysms Which Incorporate Visceral Arteries.
The registry population consists of patients presenting with complex aortic pathologies amenable to endovascular aortic repair that requires the incorporation of bridging stents to maintain visceral artery perfusion
- Conditions
- Complex Aortic Aneurysms, Thoracoabdominal Aneurysm, Fenestrated Endovascular Aortic Repair, Endovascular Aortic Repair
- Trial name
- ENVISION (NCT07480395)
- Where
- 26 sites in Austria, Denmark and 8 more
- Volunteers
- 400 people
- Sponsor
- W.L.Gore & Associates
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture
BGP+ Stent as Bridging Stent in BEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BGP+ balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany) implanted as…
- Trial name
- NCT03982940
- Testing
- BGP+ Stent Graft System as bridging stent
- Where
- 10 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Marc Bosiers, MD
Juxtarenal Aortic Aneurysm, Pararenal Aneurysm
Comparison of Outcomes of Complex Abdominal Aortic Aneurysm Treatment
Background: Open repair remains the gold standard for fit patients with complex AAA. In the past decade, an evolution of devices, design, components, and delivery systems expanded the application of EVAR in these challenging…
- Trial name
- NCT04773223
- Testing
- Open surgery and complex EVAR due to AAA
- Where
- Serbia
- Volunteers
- 925 people
- Sponsor
- Clinical Centre of Serbia
Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms
Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
The purpose of this study is to evaluate clinical outcomes and quality of life measures in treated by endovascular aortic repair of juxtarenal, suprarenal, and type IV thoracoabdominal aortic aneurysms using custom-made Cook…
- Conditions
- Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
- Trial name
- NCT01937949
- Testing
- Custom-made Zenith® Fenestrated AAA Endovascular Graft:
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Gustavo S Oderich
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm, Without Mention of Rupture
BGP Stent as Bridging Stent in FEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BeGraft Peripheral (BGP) balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany)…
- Trial name
- NCT03987035
- Testing
- BeGraft Peripheral (BGP) Stent Graft System as bridging stent
- Where
- 9 sites in Germany
- Volunteers
- 103 people
- Sponsor
- Marc Bosiers, MD
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm)
Quick Yielding Modified Short-Distance Fenestration Technique for the Treatment of Complex Aortic Arch Diseases: a Multicenter Single-Arm Objective Performance Criteria Trial(QYM-Tech Study)
Background: This study investigates the safety and efficacy of a novel surgical approach combining thoracic endovascular aortic repair (TEVAR) and in situ fenestration reconstruction of supra-aortic branches using the Quick…
- Conditions
- Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm), Thoracic Pseudoaneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT06639243
- Testing
- QYM Technique
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Complex Aortic Aneurysms, Thoracoabdominal Aneurysms
Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices
The purpose of this study is to evaluate the safety and efficacy of custom made devices, Zenith t-Branch devices and physician modification of FDA approved off-the-shelf endovascular grafts in the treatment of patients with…
- Conditions
- Complex Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aneurysms, Juxtarenal Aneurysms
- Trial name
- CARPE-CMD (NCT02050113)
- Testing
- Custom Made Fenestrated or Branched Stent Graft
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Andres Schanzer
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris