Clinical trials: Cognitive Flexibility
Alcoholism
Cognitive Vulnerability Factors in Alcohol-dependence
The purpose of this study is to specify the cognitive and genetic pattern associated with alcohol dependence. Results will help identifying more precisely vulnerability factors associated with this disorder.
- Trial name
- CoVAD (NCT02842528)
- Testing
- Diagnostic Interview for Genetic Studies, Family Informant Schedule and Criteria, Temperament and Character Inventory
- Where
- France
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Dementia, Mild Cognitive Impairment
Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia
Evidence shows that people with dementia have a higher prevalence of sleep disturbance, cognitive decline, behavioral disturbance, and experience motor dysfunction. These symptoms are interrelated.
- Conditions
- Dementia, Mild Cognitive Impairment, Older Adult
- Trial name
- DTT (NCT06348810)
- Testing
- Dual-task training, Cognitive training, Motor training
- Where
- Indonesia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Obsessive-Compulsive Disorder, Cognitive Flexiblity
Cognitive Flexibility and Response to TMS Therapy
Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option for treatment-resistant obsessive-compulsive disorder.
- Trial name
- CogFlexTMS (NCT06769243)
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Aging, Physical Activity in Adults
Health Effects of Taekwondo Training for Elderly Over the Age of 60 Years
This randomized controlled trial investigates the effects of a 10-week Taekwondo (TKD) training intervention on physical and cognitive function in community-dwelling adults aged 60 years and older.
- Trial name
- TKD 60+ (NCT07451288)
- Testing
- Taekwondo training
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vegard Vereide Iversen
Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers
Effect of a Mindfulness-Based Stress Reduction Program on Caregivers
This study is designed to investigate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on cognitive control and flexibility, psychological well-being, and self-compassion among primary caregivers of individuals…
- Conditions
- Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers, Chronic Mental Illness Caregiving, Cognitive and Emotional Outcomes in Caregivers
- Trial name
- MBSR-CG (NCT07322081)
- Testing
- The Mindfulness-Based Stress Reduction program consists of structured mindfulness practices, psychoeducation, and experiential exercises delivered to caregivers., Usual Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cognitive Flexibility Among Female Teenagers
Correlation of Anti-gravity Muscle Strength With Glycemic Control, Duration of Disease, and Neuropathy Severity in Type 2 Diabetes Mellitus.
The study suggests that the high intensity exercise training program is beneficial for the female teenagers to enhance their cognitive abilities along with the physical strengthening.
- Trial name
- T2DM-AMS (NCT05873478)
- Testing
- High Intensity Interval Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Executive Function
The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314634
- Testing
- concurrent exercise, aerobic exercise
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Mental Health Stigma, Cognitive Flexibility
Integrated Mental Health Nursing Program: Effects on Stigma, Cognitive Flexibility, and Clinical Readiness
This quasi-experimental one-group pretest-posttest study aims to evaluate the effect of an Integrated Mental Health Nursing Educational Program on stigma, cognitive flexibility, and clinical readiness among undergraduate nursing…
- Conditions
- Mental Health Stigma, Cognitive Flexibility, Clinical Readiness, Mental Health Nursing Education
- Trial name
- IMHNEP (NCT07517861)
- Testing
- Integrated Mental Health Nursing Educational Program (IMHNEP)
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Menopause, Stress, Psychological
Fascial Yoga in Menopausal Women
Aim: The aim of this study is to evaluate the effects of a structured fascial yoga-based behavioral intervention on perceived stress, cognitive control, and cognitive flexibility in menopausal women.
- Conditions
- Menopause, Stress, Psychological, Cognitive Flexibility, Nonpharmacological Interventions
- Trial name
- FascialYogaM (NCT07401810)
- Testing
- Fascial Yoga Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Alcohol Abuse, Cognitive Deficit in Attention
Pilot Study on Training Emerging Adults Skills in Navigating College
Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to…
- Trial name
- SINC (NCT05560425)
- Testing
- Koru Mindfulness (KM) Training, Navigating College (NC) Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Executive Function, Cognitive Performance
Acute Effects of Moderate-Intensity Swimming Exercise on Inhibitory Control, Cognitive Flexibility, and Selective Attention
This randomized controlled trial aims to investigate the acute effects of a single session of moderate-intensity freestyle swimming exercise on cognitive performance in healthy young adults.
- Conditions
- Executive Function, Cognitive Performance, Selective Attention, Inhibitory Control
- Trial name
- SWIMCOG (NCT07670104)
- Testing
- Moderate-Intensity Freestyle Swimming Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Görkem Açar
Schizophrenia, Attention Deficit Disorder With Hyperactivity (ADHD)
Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility
The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior.
- Trial name
- NCT07217652
- Testing
- High-resolution fMRI during working memory, cognitive control, and decision-making tasks
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kai Hwang
Anxiety Disorders
Effects of tDCS on Fear Reversal in Patients With Anxiety Disorders
This study evaluates the effects of single-session Transcranial Direct Current Stimulation (tDCS) on fear reversal learning in patients with anxiety disorders.
- Trial name
- NCT07405463
- Testing
- Cathodal tDCS (rDLPFC), Anodal tDCS (vmPFC), Anodal tDCS (lDLPFC)
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Jingchu Hu
Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene
Mod of Cognitive Flexibility by tDCS, Tyrosine Polymorphisms in the COMT Gene
The current study would examine whether increases in endogenous dopaminergic activity via tyrosine and the (presumed) excitation of these by anodal tDCS of the dlPFC could causally be related to cognitive flexibility as measured…
- Trial name
- NCT03845920
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Autism Spectrum Disorder
Flexibility and the Predictive Brain in Autistic Males and Females
The goal of this study is to compare the neural correlates of predictive brain mechanisms during high-level social and non-social flexibility tasks, between autistic and non-autistic males and females.
- Trial name
- FLEX-PREAU (NCT06391684)
- Testing
- Social/non social; predictable vs unpredictable
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Aging
Feasibility and Efficacy of A Remote Tai Chi Program in Older Adults
This project is designed to explore the feasibility and preliminary efficacy of a remote Tai Chi program on older adults' 24-hour movement behaviors (i.e., physical activity, sedentary behavior and sleep patterns).
- Trial name
- NCT06918678
- Testing
- Tai Chi intervention, Usual care condiition
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Cognitive Change
Dopamine Dorsolateral Prefrontal Cortex Behavioural Flexibility
Behavioural or cognitive flexibility (BF) is an essential ability which allows an organism to adaptively change responses in accordance with feedback of results.
- Trial name
- NCT03068884
- Testing
- Cathodal Transcranial direct current stimulation, L-Tyrosine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Healthy
Structure Learning Training and Cognitive Flexibility
The overarching aim of the project is to assess whether structure learning is an effective tool to train and improve cognitive flexibility and whether this is transferable to learning and other cognitive skills.
- Trial name
- NCT05611788
- Testing
- Structure Learning Training
- Where
- Singapore
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Smartphone, Musculoskeletal
Relationship of SmartPhone Use Addiction With Musculoskeletal System and Cognitive Flexibility
Smartphones have become a part of everyday life, but with some problems. Researches have pointed out that smartphone addiction can cause both physical and mental problems.
- Conditions
- Smartphone, Musculoskeletal, Cognitive Flexiblity
- Trial name
- NCT03772782
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
ARFID, Anorexia Nervosa
Cognitive Evaluation of Patients With Eating Disorders
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public…
- Conditions
- ARFID, Anorexia Nervosa, Bulimia Nervosa, Cognitive Flexibility
- Trial name
- DNA_ARFID (NCT07478510)
- Testing
- Go/No-go, IAT, WCST
- Where
- 3 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA