Clinical trials: Cognitive Flexibility
Alcoholism
Cognitive Vulnerability Factors in Alcohol-dependence
The purpose of this study is to specify the cognitive and genetic pattern associated with alcohol dependence. Results will help identifying more precisely vulnerability factors associated with this disorder.
- Trial name
- CoVAD (NCT02842528)
- Testing
- Diagnostic Interview for Genetic Studies, Family Informant Schedule and Criteria, Temperament and Character Inventory
- Where
- France
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Emotional Distress
The Role of Cognitive Flexibility in Mindfulness Intervention for Emotional Distress
This study hopes to: 1. explore whether offline and online mindfulness interventions can significantly alleviate individual emotional distress and improve cognitive flexibility level. 2.
- Trial name
- NCT05806281
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University
Military Personnel With High Pressure
Mindfulness-based Writing Expression Training Among Military Personnel
The goal of this clinical trial is to learn if mindfulness-based writing expression training works to improve stress and cognitive flexibility among military personnel.
- Trial name
- NCT07426341
- Testing
- mindfulness-based writing expression intervention, Regular Mental Health Education Group
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xiaofan Yan
Dementia, Mild Cognitive Impairment
Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia
Evidence shows that people with dementia have a higher prevalence of sleep disturbance, cognitive decline, behavioral disturbance, and experience motor dysfunction. These symptoms are interrelated.
- Conditions
- Dementia, Mild Cognitive Impairment, Older Adult
- Trial name
- DTT (NCT06348810)
- Testing
- Dual-task training, Cognitive training, Motor training
- Where
- Indonesia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Post Traumatic Stress Disorder
rTMS-augmented Written Exposure Therapy for PTSD
Post-traumatic stress disorder (PTSD) is prevalent and represents a high healthcare burden among Veterans. Repetitive transcranial magnetic stimulation (rTMS) is a brain-based therapy that may be effective for treating PTSD.
- Trial name
- NCT05149534
- Testing
- Written Exposure Therapy, repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- VA Office of Research and Development
Obsessive-Compulsive Disorder, Cognitive Flexiblity
Cognitive Flexibility and Response to TMS Therapy
Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option for treatment-resistant obsessive-compulsive disorder.
- Trial name
- CogFlexTMS (NCT06769243)
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Aging, Physical Activity in Adults
Health Effects of Taekwondo Training for Elderly Over the Age of 60 Years
This randomized controlled trial investigates the effects of a 10-week Taekwondo (TKD) training intervention on physical and cognitive function in community-dwelling adults aged 60 years and older.
- Trial name
- TKD 60+ (NCT07451288)
- Testing
- Taekwondo training
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vegard Vereide Iversen
Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers
Effect of a Mindfulness-Based Stress Reduction Program on Caregivers
This study is designed to investigate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on cognitive control and flexibility, psychological well-being, and self-compassion among primary caregivers of individuals…
- Conditions
- Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers, Chronic Mental Illness Caregiving, Cognitive and Emotional Outcomes in Caregivers
- Trial name
- MBSR-CG (NCT07322081)
- Testing
- The Mindfulness-Based Stress Reduction program consists of structured mindfulness practices, psychoeducation, and experiential exercises delivered to caregivers., Usual Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Tic Disorders
Efficacy of Biofeedback in the Treatment of Tic Disorder
To investigate the efficacy of EEG biofeedback and drug therapy in the treatment of tic disorders
- Trial name
- NCT05361993
- Testing
- Drug Aripiprazole, biofeedback
- Where
- China
- Sponsor
- Children's Hospital of Fudan University
Gambling Disorder
The Effect of Transcranial Direct Current Stimulation on Decision Making and Cognitive Flexibility in Gambling Disorder
The investigators conducted a double-blind randomised sham-controlled study. Upon enrollment into the study, participants were randomly assigned to one of two conditions: (i) active group: anodal stimulation over the right dlPFC…
- Trial name
- NCT03477799
- Testing
- Transcranial direct current stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University
Cognitive Flexibility Among Female Teenagers
Correlation of Anti-gravity Muscle Strength With Glycemic Control, Duration of Disease, and Neuropathy Severity in Type 2 Diabetes Mellitus.
The study suggests that the high intensity exercise training program is beneficial for the female teenagers to enhance their cognitive abilities along with the physical strengthening.
- Trial name
- T2DM-AMS (NCT05873478)
- Testing
- High Intensity Interval Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Non-specific Low-Back Pain, Chronic Non-specific Neck Pain
Diaphragmatic Breathing Training in Chronic Spinal Pain
The goal of this clinical trial is to learn whether adding breathing training to an exercise program can improve pain, mood, and thinking skills in adults with chronic spinal pain.
- Trial name
- NCT07539116
- Testing
- Structured Exercise program, Diaphragmatic Breathing Training
- Where
- 2 sites in Greece
- Volunteers
- 183 people
- Sponsor
- Democritus University of Thrace
Anorexia Nervosa, Atypical Anorexia Nervosa
Ketamine Effects on Learning In Eating Disorders
This is a single site, single dose clinical trial of intravenous (IV) ketamine for medically hospitalized adolescents and young adults with anorexia nervosa or atypical anorexia nervosa.
- Trial name
- KETTLE (NCT06736769)
- Testing
- Ketamine infusion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Amanda Downey, MD
Executive Function
The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314634
- Testing
- concurrent exercise, aerobic exercise
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Emotional Distress
Mechanism of Mindfulness-Based Online Intervention in Enhancing Cognitive Flexibility
Traditional offline interventions such as MBCT and MBSR have been implemented to treat patients with emotional disorders and obtained significantly improved clinical outcomes.
- Trial name
- NCT06035003
- Testing
- Internet-based Mindfulness Intervention for Emotional Distress (iMIED)
- Where
- China
- Volunteers
- 595 people
- Sponsor
- Peking University
Depressive Disorder, Major, Cognitive Impairment
Brain Functional Connectivity Mechanism of Cognitive Flexibility Impairment and rTMS Intervention in Major Depressive Disorder
Major depressive disorder (MDD) often involves cognitive deficits, particularly in cognitive flexibility, which is inadequately addressed by standard antidepressants.
- Trial name
- NCT07161492
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Second Xiangya Hospital of Central South University
Mental Health Stigma, Cognitive Flexibility
Integrated Mental Health Nursing Program: Effects on Stigma, Cognitive Flexibility, and Clinical Readiness
This quasi-experimental one-group pretest-posttest study aims to evaluate the effect of an Integrated Mental Health Nursing Educational Program on stigma, cognitive flexibility, and clinical readiness among undergraduate nursing…
- Conditions
- Mental Health Stigma, Cognitive Flexibility, Clinical Readiness, Mental Health Nursing Education
- Trial name
- IMHNEP (NCT07517861)
- Testing
- Integrated Mental Health Nursing Educational Program (IMHNEP)
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Menopause, Stress, Psychological
Fascial Yoga in Menopausal Women
Aim: The aim of this study is to evaluate the effects of a structured fascial yoga-based behavioral intervention on perceived stress, cognitive control, and cognitive flexibility in menopausal women.
- Conditions
- Menopause, Stress, Psychological, Cognitive Flexibility, Nonpharmacological Interventions
- Trial name
- FascialYogaM (NCT07401810)
- Testing
- Fascial Yoga Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Alcohol Abuse, Cognitive Deficit in Attention
Pilot Study on Training Emerging Adults Skills in Navigating College
Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to…
- Trial name
- SINC (NCT05560425)
- Testing
- Koru Mindfulness (KM) Training, Navigating College (NC) Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Executive Function, Cognitive Performance
Acute Effects of Moderate-Intensity Swimming Exercise on Inhibitory Control, Cognitive Flexibility, and Selective Attention
This randomized controlled trial aims to investigate the acute effects of a single session of moderate-intensity freestyle swimming exercise on cognitive performance in healthy young adults.
- Conditions
- Executive Function, Cognitive Performance, Selective Attention, Inhibitory Control
- Trial name
- SWIMCOG (NCT07670104)
- Testing
- Moderate-Intensity Freestyle Swimming Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Görkem Açar