Clinical trials: Chronic Mental Disorder
Chronic Pain, Opioid-Related Disorders
Transforming Opioid Prescribing in Primary Care
Prescription opioid misuse is a significant public health problem as well as a patient safety concern. Primary care providers are the leading prescribers of opioids for chronic pain, yet few providers follow standard practice…
- Trial name
- TOPCARE (NCT01909076)
- Testing
- Electronic decision support tools, Enhanced patient education materials, Nurse care management
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Chronic Sleep Disorders, Anxiety Disorder
Effect of Transcranial Alternating Current Stimulation on Sleep Disorder and Anxiety in Elderly Population
Sleep disorders and anxiety are complicated disorders affecting population especially elderly population, therefore treating these disorders will have positive impact on population production and quality of life.
- Trial name
- NCT07147582
- Testing
- Transcranial alternating current stimulation with two electrodes placed on scalp
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Prodromal Schizophrenia, Prodromal Psychosis
Aripiprazole Treatment of the Prodrome
The RAP Program is conducting a research study of the antipsychotic medication Aripiprazole. This drug has been approved for treating symptoms associated with schizophrenia and is associated with fewer side effects.
- Trial name
- NCT00169949
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Mental Disorders, Drug Addiction
Treatment of Hepatitis C in Psychiatric Patients
Psychiatric disorders or drug addiction are often regarded as contraindications against the use of Interferon-alpha in patients with chronic hepatitis C.
- Trial name
- NCT00751426
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Neck Pain
Pain, Fear of Movement, Neck Awareness and Upper Extremity Functionality in Chronic Neck Pain
Our study aims to investigate the parameters related to pain catastrophizing, fear of movement, neck awareness and upper extremity functionality in individuals with chronic neck pain - a cross-sectional study.
- Trial name
- NCT07247214
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Disorder of Consciousness
Metabolic Abnormalities and Intestinal Microecology in Patients With Chronic Disorders of Consciousness
Following severe traumatic brain injury, patients may remain unconscious for many years. It is the intestinal microbiome and metabolomics analysis comparing differentially intestinal microflora and metabolites between patients…
- Trial name
- NCT04530968
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Insomnia Chronic, Posttraumatic Stress Disorder
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
This is a proof-of-concept, open-label trial of pimavanserin 34mg at bedtime for 6 weeks in Veterans with insomnia and Posttraumatic Stress Disorder.
- Trial name
- NCT04809116
- Testing
- Pimavanserin
- Where
- United States
- Sponsor
- Baylor College of Medicine
COPD, Depression
The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity
Chronic Obstructive Pulmonary Disease (COPD) is prevalent and debilitating chronic disease in Veterans. COPD is highly co-morbid with depression and anxiety conferring greater morbidity and mortality risk.
- Conditions
- COPD, Depression, Anxiety
- Trial name
- NCT04953806
- Testing
- Step-CBT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Insomnia, COPD
A Behavioral Therapy for Insomnia Co-existing With COPD
Difficulty falling asleep, staying asleep or poor quality sleep (insomnia) is common in people with chronic obstructive pulmonary disease.
- Conditions
- Insomnia, COPD, Chronic Obstructive Pulmonary Disease, Fatigue
- Trial name
- NCT01973647
- Testing
- Cognitive Behavioral Therapy for Insomnia, COPD Education, Attention Control
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Illinois at Chicago
Insomnia Chronic, Insomnia
Assessment of Usability and Preliminary Effectiveness of a Digital Sleep Aid in an Italian Sample
Chronic insomnia affects approximately 30% of the Italian population, leading to significant impairments in daily functioning and overall health.
- Trial name
- REST (NCT06926348)
- Testing
- Digital Health Technology for Chronic Insomnia, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Universita di Verona
Depression, Family Dynamics
The Mental Health Effects of a Mindfulness App in Parents of a Child With Medical Complexity
The number of children with special health care needs (CSHCN) in the US is nearly 20% of children representing approximately 14.6 million children nationally.
- Conditions
- Depression, Family Dynamics, Stress, Psychological, Chronic Illness
- Trial name
- NCT05925868
- Testing
- mindfulness app
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Boise State University
Chronic Pain, Addiction Opiate
Cross-cultural Validation of a Screening Scale for the Misuse of Opioid Analgesics in Primary Care
Objective: Analgesic Opioids misuse among patients with chronic pain ranges from 0% to 50%. The general practitioner is the first prescriber of opioid analgesics Our objective was to validate in primary care the POMI…
- Trial name
- VAMOS (NCT05431985)
- Where
- 5 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive
Transforming Psychotherapy for Chronically Ill Patients
The primary objective of this research is to pilot test a brief mental heath treatment specifically tailored to meet the needs of chronically ill patients with anxiety and/or depression.
- Conditions
- Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive, Depression, Anxiety
- Trial name
- NCT00520429
- Testing
- ACCES - Adjusting to Chronic Conditions with Education and Support
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Pain
MIVetsCan: Can-Coach Trial (Phase 2)
The goal of the MIVetsCan Can-Coach Trial is to test four coaching sessions to help Veterans with chronic pain use their own cannabis products more effectively to manage pain and related symptoms.
- Trial name
- NCT06283862
- Testing
- Educational Session
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- University of Michigan
Low Back Pain, Kinesiophobia (Fear of Movement)
Feasibility of an Augmented Reality Novel Approach for the Rehabilitation of Chronic Low Back Pain Patients With Kinesiophobia
The goal of this clinical trial is to evaluate the feasibility, safety, and initial effectiveness of a new augmented reality (AR) system in adults over 18 years old suffering from chronic low back pain and kinesiophobia (fear of…
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Healty Volunteers
- Trial name
- NCT07527845
- Testing
- Augmented Reality (AR) Rehabilitation System
- Where
- Chile
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Chronic Pain
Evaluation of an Opioid Decrease Strategy in Chronic
Increase in the consumption of analgesics observed in many countries with a mediatic crisis resulting in an increasingly frequent wish of patients to wean themselves from opiates. A recent update (B.
- Trial name
- EODSCPP (NCT04424459)
- Testing
- opioid withdrawal
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Covid19, Chronic Kidney Diseases
Physical Activity Level in Patients with Chronic Kidney Disease During COVID-19 Pandemic
In the literature, there are no studies evaluating fear of COVID-19, anxiety, depression, physical activity, fear of movement and quality of life in patients with chronic kidney disease during COVID-19 pandemic.
- Trial name
- NCT04745923
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Child, Only, Chronic Renal Failure in Children
The Effect of a Mobile Game Application on Children With CRF
The aim of this study was to investigate the effect of a mobile game application developed for children with Chronic Renal Failure (CRF) on disease management. The study was a randomized controlled trial.
- Conditions
- Child, Only, Chronic Renal Failure in Children, Gambling, Disease
- Trial name
- NCT07162220
- Testing
- The clinic's routine education program, Mobile game app
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Akdeniz University