Clinical trials: Cervical Spinal Stenosis
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis
Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion
The purpose of this study is to evaluate the safety and preliminary efficacy of NeoFuse in subjects with a diagnosis of degenerative disc disease (DDD) at 2 or more adjacent cervical vertebral levels between C3-C4 to C7-T1.
- Conditions
- Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT01106417
- Testing
- NeoFuse, MasterGraft Granules
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Mesoblast, Ltd.
Pain, Cervical Spinal Stenosis
KT® in Patients With Cervical Spine Surgery
Aim of the study was to investigate the effect of Kinesio taping application on upper trapezius muscle after cervical spine surgery.
- Conditions
- Pain, Cervical Spinal Stenosis, Disc, Herniated, Cervical Spondylosis
- Trial name
- NCT04039581
- Testing
- Kinesio Taping, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Degenerative Cervical Kyphosis With Stenosis
Anterior Spinal Canal Reconstruction and Fusion Surgery for Treating Degenerative Cervical Kyphosis With Stenosis
Degenerative cervical kyphosis with stenosis (DCKS) is a common cervical spine degenerative disease, causing pain, numbness, and weakness of limbs, which seriously affect the quality of life of the patient.
- Trial name
- NCT04806360
- Testing
- ACRF surgery, conventional anterior surgery, conventional posterior surgery
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Changzheng Hospital
Cervical Spinal Stenosis
Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block
The purpose of this study is to analyze the spread of local anesthetic using magnetic resonance imaging after thoracic 2 paravertebral block in patients with cervical radiculopathy.
- Trial name
- NCT05141136
- Testing
- Ultrasound probe sagittal group, Ultrasound probe transverse group
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Gangnam Severance Hospital
Cervical Spinal Stenosis, Cervical Spinal Cord Injury
Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis
To evaluate the safety and effectiveness of individualized, precise and standardized open-door posterior cervical surgery through a single-center, exploratory clinical study, so as to provide a more reliable basis for the…
- Conditions
- Cervical Spinal Stenosis, Cervical Spinal Cord Injury, Individuation, Standardization
- Trial name
- NCT05786313
- Testing
- Centerpiece titanium plate
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Spinal Stenosis, Back Pain
Postural Balance and Stability Among Patients With Cervical and Back Pain
High percentage of chronic back pain is due to spinal stenosis. The clinical picture is of 'neurogenic claudication' which effects postural balance and stability.
- Trial name
- NCT02395887
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Degenerative Cervical Spinal Stenosis
A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity
Degenerative Cervical Myelopathy (DCM) is an age-related irreversible degenerative disease predominantly affecting the elderly aged 50 and over.
- Trial name
- NCT06528730
- Testing
- DCM
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Low Back Pain, Neck Pain
Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders
The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for…
- Conditions
- Low Back Pain, Neck Pain, Disc Herniation, Disc Degeneration
- Trial name
- AID-Spine (NCT05745129)
- Where
- Norway
- Volunteers
- 165,000 people
- Sponsor
- Oslo Metropolitan University
Spinal Stenosis Cervical, Radiculopathy, Cervical Region
Hard Cervical Collar Use Following Posterior Cervical Fusion
Postoperative immobilization with a hard cervical collar following posterior cervical fusion remains common practice despite limited evidence demonstrating improved clinical outcomes.
- Conditions
- Spinal Stenosis Cervical, Radiculopathy, Cervical Region, Posterior Cervical Fusion, Spondylosis, Cervical
- Trial name
- NCT07789288
- Testing
- Hard Cervical Collar
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Georgetown University
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis
Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy
The purpose of this study is to evaluate the safety and preliminary efficacy of NeoFuse in subjects with a diagnosis of degenerative disc disease (DDD) at 2 or more adjacent cervical vertebral levels between C3-C4 to C7-T1.
- Conditions
- Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT01097486
- Testing
- NeoFuse, Allograft
- Where
- 8 sites in United States
- Volunteers
- 24 people
- Sponsor
- Mesoblast, Ltd.
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Degenerative Disc Disease in Cervical Spine, Stenosis Cervical Spine
PMCF Study Fortilink-SC
This study is setup to be able to gather information on the safety and performance of the Fortilink-SC Ti cage of Paradigm Spine GmbH, up to one year after the surgery.
- Trial name
- NCT07834749
- Testing
- Cervical interbody fusion surgery (standalone)
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- BAAT Medical Products B.V.
Degenerative Spinal Arthritis, Cervical Myelopathy
Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion
This research study is being conducted to help improve the pre-operative, intra-operative, and post-operative course for patients and enhance recovery.
- Conditions
- Degenerative Spinal Arthritis, Cervical Myelopathy, Spinal Stenosis
- Trial name
- NCT04315090
- Sponsor
- Mayo Clinic
Spinal Stenosis Occipito-Atlanto-Axial, Spinal Disease
Streamline Occipito-Cervico-Thoracic System Post-Market Clinical Follow-up
This is a multi-center, post-market, retrospective study design to collect safety and performance data for patients implanted with the Streamline OCT System.
- Conditions
- Spinal Stenosis Occipito-Atlanto-Axial, Spinal Disease, Spinal Stenosis Cervical, Spinal Stenosis Cervicothoracic Region
- Trial name
- OCT PMCF (NCT04171544)
- Testing
- Streamline Occipito-Cervico-Thoracic Spinal Fixation System
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- RTI Surgical
Cervical Spinal Stenosis, Posterior Cervical Spine Surgery
Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical Surgery
Through a single-center, exploratory clinical study, the safety and effectiveness of using barb wire in the incision and suture of posterior cervical surgery in obese patients were evaluated, providing a basis for its wide…
- Conditions
- Cervical Spinal Stenosis, Posterior Cervical Spine Surgery, Barbed Suture
- Trial name
- NCT05895968
- Testing
- posterior cervical surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle