Clinical trials: Cerebrovascular Accident
Stroke
Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients
The purpose of this study is to identify and establish how the area of the brain that controls motor function (motor cortex) of the non-affected hemisphere after stroke might serve as a new target for therapeutic interventions to…
- Trial name
- NCT02544503
- Testing
- Single-pulse Transcranial Magnetic Stimulation (TMS), Paired-pulse Transcranial Magnetic Stimulation (ppTMS), Low-frequency Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Emory University
Cerebral Infarction, Stroke, Acute
Medication Intake of Solid Dosage Forms: A Risk Factor for Patients With Stroke-induced Dysphagia?
In a prospective, quantitative explorative study, the risk of aspiration and penetration when swallowing solid pills (placebo) compared to a crushed placebo pill will be evaluated during a routine Fiberoptic Endoscopic Evaluation…
- Conditions
- Cerebral Infarction, Stroke, Acute, Stroke, Dysphagia
- Trial name
- MedISID (NCT05173051)
- Testing
- Solid Medication intake vs. crushed medication intake
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Motor Recovery
BreEStim for Post-Stroke Motor Recovery
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750551
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to improve learning of movement skills and the adaptation processes in patients after stroke.
- Trial name
- NCT00715520
- Testing
- Transcranial Magnetic Stimulation (TMS), Carbidopa-Levodopa, Methylphenidate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke
Effect of Pilates Training on Cognitive Functions in Patients With Stroke
The purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke
- Trial name
- NCT04157582
- Testing
- Pilates training, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Atrial Septal Aneurysm
Transcatheter Exclusion of Atrial-septal-aneurysm (TEA)
This study aims to investigate the safety and efficacy of transcatheter exclusion of atrial septal aneurysm (ASA) via transseptal perforation in patients with ASA.
- Trial name
- TEA (NCT04561882)
- Testing
- Transcatheter exclusion of atrial septal aneurysm
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- China National Center for Cardiovascular Diseases
CVA (Cerebrovascular Accident), Cerebral Hemorrhage
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving…
- Conditions
- CVA (Cerebrovascular Accident), Cerebral Hemorrhage, Intracranial Hemorrhages
- Trial name
- NCT00226096
- Testing
- Labetalol Hydrochloride, Metoprolol tartrate, Hydralazine Hydrochloride
- Where
- 20 sites in Australia, China and 1 more
- Volunteers
- 404 people
- Sponsor
- The George Institute
Stroke, Pain
Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb.
- Conditions
- Stroke, Pain, Impaired Motor Function
- Trial name
- MiraPi (NCT06842888)
- Testing
- Miraπ, Mirror Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Arterial Ischemic Stroke
A Proof of Concept Study to Evaluate the Safety of Afamelanotide in Patients With Acute Arterial Ischaemic Stroke (AIS)
The primary study objective is to assess the safety of afamelanotide while the secondary objective is to assess whether the therapy affects the size of the penumbra, by increasing blood flow, restoring oxygen supply to the brain…
- Trial name
- NCT04962503
- Testing
- Afamelanotide
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Stroke, Brain Injuries
Investigating Usability of c-SIGHT in the Homes of Brain Injury Survivors
A brain injury can damage the brain, so that it no longer receives information about the space around one side of the world. If this happens, people may not be aware of anything on one side, usually the same side they also lost…
- Conditions
- Stroke, Brain Injuries, Spatial Neglect, Attention Deficit
- Trial name
- c-SIGHT (NCT03963661)
- Testing
- c-SIGHT (computorized spatial innatention grasping home-based therapy)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of East Anglia
Cadasil
AusCADASIL: An Australian Cohort of CADASIL
The aim of this project is to establish an Australian cohort of patients diagnosed with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL).
- Trial name
- NCT06148051
- Where
- 5 sites in Australia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Perminder Sachdev
Cerebrovascular Accident
To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients
The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be randomized into two groups: AB and BA.
- Trial name
- NCT02410629
- Testing
- Music Glove, Conventional Hand Exercise Program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- David Reinkensmeyer
Stroke
Closed-loop Sensorimotor Integrated (CSMI) Control in Exoneuromusculoskeleton (ENMS) for Precise Wrist-hand Rehabilitation After Stroke
The goal of this randomized controlled trial is to determine whether using both brain and muscle signals to control a wrist-hand rehabilitation robot can improve recovery in people with chronic stroke.
- Trial name
- NCT07737431
- Testing
- CSMI-Controlled ENMS, EMG-Driven ENMS
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Acute Stroke Patients Requiring Invasive Mechanical Ventilation
Stroke Prognosis in Intensive CarE
The S.P.I.C.E registry is an investigator-initiated prospective multicenter cohort study which will be conducted in 35 ICUS in the Paris area.The aim of the study is to determine the trajectory of acute stroke patients requiring…
- Trial name
- SPICE (NCT03335995)
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke, Disability Physical
Adaptation and Validation of the LUNS for Use in Turkey.
According to the most up-to-date knowledge, there is no Turkish comprehensive and validated instrument to assess stroke survivors' unmet needs in the longer term.
- Conditions
- Stroke, Disability Physical, Quality of Life
- Trial name
- NCT06278805
- Testing
- The reliability and validity study of the T-LUNS
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Uşak University
Upper Motor Neuron Disease
Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients
To determine whether Spatially Distributed Sequential Functional Electrical Stimulation is more effective than Standard Electrical Stimulation During Functional Electrical Stimulation in Upper Motor Neuron Patients
- Trial name
- SDSS_UMS (NCT06421753)
- Testing
- SDSS, Standard Electrical Stimulation During Functional Electrical Stimulation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- UGECAM Rhône-Alpes
Stroke
Treadmill Training With Functional Electric Stimulation After Stroke
The purpose of this study was to investigate the effects of the treadmill training with functional electric stimulation on sensorimotor cortical reorganization and functional improvement in subjects with chronic stroke.
- Trial name
- NCT02812472
- Testing
- Treadmill training with functional electrical stimulation, Treadmill training without functional electrical stimulation
- Volunteers
- 18 people
- Sponsor
- National Yang Ming Chiao Tung University
Stroke, Sarcopenia
Evaluating and Monitoring Physical Fatigue While Performing Functional Activities
Fatigue is a critical health parameter in older adults and stroke patients and is associated with negative health outcomes. Current assessment tools predominantly focus on walking related fatigue, neglecting other activities of…
- Conditions
- Stroke, Sarcopenia, Fatigue
- Trial name
- NCT06513377
- Testing
- Performance test
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Stroke
Post-Stroke Walking Speed and Community Ambulation Conversion Study
The purpose of this randomized, controlled study is to collect performance data on the ability of an investigational device designed to digitally deliver Rhythmic Auditory Stimulation to improve walking speed in people who…
- Trial name
- NCT04121754
- Testing
- MR-001, Active Walking
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- MedRhythms, Inc.
Ischemic Stroke
Managing Aftercare for Stroke (MAS): MAS-I - a Cross Sectional Study of Post-rehabilitation Stroke Burden and Patients' Needs
In this first step of the study the investigators will assess the needs, disease burden and current treatments of long-term stroke patients (phase MAS-I).
- Trial name
- MAS-I (NCT02320994)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Charite University, Berlin, Germany
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