StrokeMiraPiNCT06842888
Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy
A study testing Miraπ and Mirror Therapy in people with Stroke and Pain, run by Yale University at 1 site in United States.
Trial summary
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb. This study will use two parallel groups: (1) receiving conventional mirror therapy as a part of the standard of care as conducted by the… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke, Pain, Impaired Motor Function
- What is being tested?
- Miraπ and Mirror Therapy
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 siteUnited States
- Study dates
- 31 Mar 2025to 19 Aug 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Participants currently accepted and cleared for rehabilitation in the inpatient rehabilitation unit by the rehabilitation medical director.
- Participants with paralysis or motor function problems of only one hand.
- Participants need mirror therapy because of their health condition.
- Participants' rehabilitation physician determined that mirror therapy would be appropriate for standard of care.
- Participants are able to memorize easy tasks, and able to follow instructions e.g., moving the healthy fingers.
Who cannot join
- Participants who are not cleared physically or medically to participate in standard acute inpatient rehabilitation therapies by the rehabilitation medical director
- Participants who are not able to memorize easy tasks, e.g., moving the healthy fingers.
- Participants with spasticity of the affected hand (as assed by the occupational therapist)
- Minors
- Vulnerable populations
Trial locations and contacts
1 site in 1 country.
United States1 site
Rehabilitation and Wellness Center at the Milford Campus of Bridgeport Hospital
Milford, Connecticut, 06460
About this study
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb.
This study will use two parallel groups: (1) receiving conventional mirror therapy as a part of the standard of care as conducted by the participant's clinical care team and (2) receiving mirror therapy with the Miraπ device as conducted by study personnel with the oversight of the participant's clinical care team.
- Conditions
- Stroke, Pain, Impaired Motor Function
- Being tested
- Miraπ, Mirror Therapy
- Medical subject headings
- Stroke, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
MiraπDevice
This device has tiny sensors that measure the movement of the healthy fingers and tiny motors that move the affected fingers of the patient.
The device is connected to a specially designed finger mechanism that moves the affected fingers of the patient. This opening mechanism is designed in a way that it prevents the fingers from being forced into any hurting position. If the patient moves the healthy fingers during training, also the fingers of the affected hand are moved by the device at the same time. This creates the effect of mirror therapy for the brain as the patient can see both hands moving.
Mirror TherapyBehavioural
Current standard of care using MT.
| Study group | Role | What they receive |
|---|---|---|
| Conventional Therapy Group | Active comparator | Participants in this group with train using Mirror Therapy (MT), the current standard of care, performing it on the affected arm for 15 minutes daily, 3 days per week until their discharge from clinic (approximately 2-3 weeks). Receives: Behavioral: Mirror Therapy |
| Miraπ Group | Experimental | Participants in this group will train with the Miraπ device, performing it on the affected arm for 15 minutes daily, 3 days per week until their discharge from clinic (approximately 2-3 weeks). Receives: Device: Miraπ |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Jebsen-Taylor Hand Function Test score
Percentage score, which determines how well a participant can do motor tasks for range of motion, strength, and tasks of activities of daily life. Participants have up to 120 seconds to complete tasks. Lower scores indicate less impairment.
Measured: At baseline and at discharge (approximately 2-3 weeks after baseline)
McGill Pain Questionnaire (MPQ)
The MPQ is scored by summing the values of words that best describe a person's pain. The score ranges from 0 (no pain) to 78 (severe pain)
Measured: At baseline and at discharge (approximately 2-3 weeks after baseline)
Change in Visual Analog Scale (VAS) to assess Pain
The VAS pain scale is a tool for assessing pain intensity. Participants will be asked to mark a point on a 100 mm horizontal line that represents the intensity of their pain. This line has two endpoints: 0: No pain and 100: Worst possible pain imaginable. The distance from the "0" to the mark is measured in millimeters with the resulting number (0-100) being the VAS pain score
Measured: At baseline and at discharge (approximately 2-3 weeks after baseline)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Feb 2025
- Study start31 Mar 2025
- Primary completion19 Aug 2025
- Study completion19 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Yale UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Inpatients undergoing inpatient rehabilitation in the IRU (inpatient rehabilitation unit) at the Yale New Haven Hospital Rehabilitation and Wellness Center
- Masking
- None (open label)
- Enrolment
- 24 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yale University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Necolle Morgado-Vega, Principal investigator, Yale University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06842888
- Sponsor's protocol ID
- 2000039425
- Acronym
- MiraPi
- Status last verified
- Dec 2025
- First submitted
- 18 Feb 2025
- Last updated
- 19 Dec 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy
- ClinicalTrials.gov ID
- NCT06842888
- Acronym / sponsor ID
- MiraPi / 2000039425
- Conditions
- Stroke, Pain, Impaired Motor Function
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 24 participants (actual)
- Lead sponsor
- Yale UniversityUniversity, hospital or other
- Study start
- 31 Mar 2025 (actual)
- Primary completion
- 19 Aug 2025 (actual)
- Study completion
- 19 Aug 2025 (actual)
- First posted
- 24 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb.
This study will use two parallel groups: (1) receiving conventional mirror therapy as a part of the standard of care as conducted by the participant's clinical care team and (2) receiving mirror therapy with the Miraπ device as conducted by study personnel with the oversight of the participant's clinical care team.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Inpatients undergoing inpatient rehabilitation in the IRU (inpatient rehabilitation unit) at the Yale New Haven Hospital Rehabilitation and Wellness Center
| Arm | Type | Receives |
|---|---|---|
| Conventional Therapy Group | Active comparator | Behavioral: Mirror TherapyParticipants in this group with train using Mirror Therapy (MT), the current standard of care, performing it on the affected arm for 15 minutes daily, 3 days per week until their discharge from clinic (approximately 2-3 weeks). |
| Miraπ Group | Experimental | Device: MiraπParticipants in this group will train with the Miraπ device, performing it on the affected arm for 15 minutes daily, 3 days per week until their discharge from clinic (approximately 2-3 weeks). |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Participants currently accepted and cleared for rehabilitation in the inpatient rehabilitation unit by the rehabilitation medical director.
- Participants with paralysis or motor function problems of only one hand.
- Participants need mirror therapy because of their health condition.
- Participants' rehabilitation physician determined that mirror therapy would be appropriate for standard of care.
- Participants are able to memorize easy tasks, and able to follow instructions e.g., moving the healthy fingers.
Key exclusion criteria (5 listed)
- Participants who are not cleared physically or medically to participate in standard acute inpatient rehabilitation therapies by the rehabilitation medical director
- Participants who are not able to memorize easy tasks, e.g., moving the healthy fingers.
- Participants with spasticity of the affected hand (as assed by the occupational therapist)
- Minors
- Vulnerable populations
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| MiraπThis device has tiny sensors that measure the movement of the healthy fingers and tiny motors that move the affected fingers of the patient. The device is connected to a specially designed finger mechanism that moves the affected fingers of the patient. This opening mechanism is designed in a way that it prevents the fingers from being forced into any hurting position. If the patient moves the healthy fingers during training, also the fingers of the affected hand are moved by the device at the same time. This creates the effect of mirror therapy for the brain as the patient can see both hands moving. | Device | Miraπ Group |
| Mirror TherapyCurrent standard of care using MT. | Behavioural | Conventional Therapy Group |
Primary outcome
Change in Jebsen-Taylor Hand Function Test score
Time frame: At baseline and at discharge (approximately 2-3 weeks after baseline)
Percentage score, which determines how well a participant can do motor tasks for range of motion, strength, and tasks of activities of daily life. Participants have up to 120 seconds to complete tasks. Lower scores indicate less impairment.
McGill Pain Questionnaire (MPQ)
Time frame: At baseline and at discharge (approximately 2-3 weeks after baseline)
The MPQ is scored by summing the values of words that best describe a person's pain. The score ranges from 0 (no pain) to 78 (severe pain)
Change in Visual Analog Scale (VAS) to assess Pain
Time frame: At baseline and at discharge (approximately 2-3 weeks after baseline)
The VAS pain scale is a tool for assessing pain intensity. Participants will be asked to mark a point on a 100 mm horizontal line that represents the intensity of their pain. This line has two endpoints: 0: No pain and 100: Worst possible pain imaginable. The distance from the "0" to the mark is measured in millimeters with the resulting number (0-100) being the VAS pain score
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Necolle Morgado-Vega principal investigator
Yale University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Miraπ and Mirror Therapy in people with Stroke and Pain, run by Yale University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Jebsen-Taylor Hand Function Test score (time frame: At baseline and at discharge (approximately 2-3 weeks after baseline)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Dec 2025.