Clinical trials: Cardiac Pacing, Artificial
Disorder of Pacing Function
3D Echocardiographic Assessment of Epicardial Pacing After Cardiopulmonary Bypass.
This study evaluates the usefulness of 3D echocardiography to guide pacemaker therapy in the operating room in cardiac surgical patients. Each patient will serve as his own control, following a paired design.
- Trial name
- NCT02842762
- Testing
- Right ventricular epicardial pacing, cardiac surgery, 3D TEE
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Suzanne Flier, MD
Atrial Fibrillation, Cardiac Pacing, Artificial
Dual Chamber Versus Single Chamber Cardiac Pacing in People 80 Years of Age and Older
Of the 19,000 pacemakers implanted across Canada in 2002, 1/3 of them were for patients 80 years and older. This is the fastest growing segment of our population, yet no study has specifically been done in this age group to…
- Trial name
- NCT00116987
- Testing
- Dual chamber cardiac pacemaker, Single chamber cardiac pacemaker
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
Heart Failure, Congestive, Cardiac Pacing, Artificial
Effect of Targeting Left Ventricular Lead Position on the Rate of Response to Cardiac Resynchronization Therapy.
Identifying \& optimizing strategies to reduce the burden of heart failure is vital. Despite advances in pharmacotherapy, patients with heart failure are at high risk for death \& hospitalization.
- Conditions
- Heart Failure, Congestive, Cardiac Pacing, Artificial, Defibrillators
- Trial name
- INCREMENTAL (NCT00399594)
- Testing
- A, B
- Where
- 3 sites in Canada
- Volunteers
- 96 people
- Sponsor
- University of Calgary
Sick Sinus Syndrome
RV Septal Versus Minimized RV Pacing in Sick Sinus Syndrome
Background: Potential negative effects of pacing in the RV-apex are well documented However, study results comparing septal / RVOT-pacing versus RV-apical pacing controversial.
- Trial name
- VOTE (NCT01477138)
- Testing
- pacemaker implantation, AAI(R)-DDD(R) versus DDD(R)
- Where
- Germany
- Volunteers
- 126 people
- Sponsor
- Klinikum Nürnberg
Cardiac Electrophysiology
Transvenous Lead Removal Post-Market Clinical Study
This prospective, multicenter, post-market clinical study was designed to evaluate the outcomes of lead extraction of cardiovascular implantable electronic devices (CIED) using Cook catheter and lead extraction devices for any…
- Trial name
- NCT03688412
- Testing
- Cook lead extraction devices
- Where
- 9 sites in United States, Germany and 2 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Cook Research Incorporated
Sick Sinus Syndrome
Mode Evaluation in Sick Sinus Syndrome Trial (MODEST)
The purpose of this study is to determine the incidence of atrial fibrillation and heart failure in patients with pacemaker therapy with different pacing modes (AAI, DDD, and a novel algorithm to minimize ventricular pacing).
- Trial name
- NCT00161551
- Testing
- Vitatron T70 DR
- Where
- 5 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Medtronic BRC
Cardiac Pacing, Artificial, Aneurysm, Brain
Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Study Concerning the Safety for Heart and Brain
Rapid ventricular pacing (RVP) is a technique to obtain flow arrest for short periods of time during dissection or rupture of the aneurysm. RVP results in an adequate fall in blood pressure which presents as an on-off phenomenon.
- Conditions
- Cardiac Pacing, Artificial, Aneurysm, Brain, Arteriovenous Malformations, Cerebral
- Trial name
- NCT03184233
- Testing
- Rapid ventricular pacing, No rapid ventricular pacing
- Where
- Belgium
- Volunteers
- 59 people
- Sponsor
- University Hospital, Antwerp
Left Bundle Branch Pacing, Heart Failure
Left Bundle Branch Area Pacing 3D Guidance System
The investigator's project proposes the development of a 3D hybrid guidance system which has the aim of avoidance of scar and septal perforation through targeted lead deployment via a personalised septal real time image overlay…
- Conditions
- Left Bundle Branch Pacing, Heart Failure, Bradycardia
- Trial name
- NCT06461715
- Testing
- Machine learning with artificial intelligence software program
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cardiac Pacing,Artificial, Coronary Artery Bypass
Biventricular Pacing After Coronary Artery Bypass Grafting (BIVAC)
The purpose of this study is to determine which pacing mode after coronary artery bypass grafting in patients with reduced left ventricular function is hemodynamically favorable.
- Conditions
- Cardiac Pacing,Artificial, Coronary Artery Bypass, Ventricular Function, Left
- Trial name
- NCT00417092
- Testing
- Postoperative Pacing
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Schleswig-Holstein
Cardiac Failure
Temporary Epicardial Cardiac Resynchronisation.
This trial will investigate the clinical and haemodynamic effects of temporary biventricular pacing after cardiac surgery. Subjects with poor left ventricular systolic function will receive either temporary biventricular pacing…
- Trial name
- NCT01027299
- Testing
- Biventricular pacing
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Cardiff and Vale University Health Board
Pacemaker, Artificial, Cardiomyopathies
Genetic Basis of Pacing-induced Cardiomyopathy
The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.
- Trial name
- NCT03317964
- Testing
- Saliva sample
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- The Guthrie Clinic
Arrhythmia, Bradycardia
CAPTURE - Complete Automatic Pacing Threshold Utilization Recorded by EnPulse
This study compares the pacemaker's automatic pacing threshold measurements to the manual measurements conducted by a health care provider.
- Trial name
- NCT00275769
- Testing
- Pacemaker
- Where
- 57 sites in United States, Canada
- Volunteers
- 860 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiac Pacing Indication classI/IIa According AHA/ACC
Progressive Ventricular Dysfunction Prevention in Pacemaker Patients
The purpose of this pilot study is to evaluate the progression of ventricular dysfunction in patients with ventricular dysfunction within the permanent pacing population.
- Trial name
- Prevent-HF (NCT00170326)
- Testing
- dual-chamber pacemaker implantation, biventricular dual-chamber pacemaker implant
- Where
- 5 sites in Spain
- Volunteers
- 108 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Optimize RV Selective Site Pacing Clinical Trial
The purpose of the Optimize RV study is to determine the long-term effect of selective site pacing. Selective site pacing refers to which area of the right ventricle the lead is placed.
- Trial name
- NCT00422669
- Testing
- Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
- Where
- 22 sites in United States, Canada and 4 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiac Pacing, Artificial
Transcoronary Pacing and Myocardial Viability
Narrowing of the coronary arteries can cause chest pain and weaken the heart. In patients who have had heart attacks, blocked or severely narrowed arteries should be investigated (with coronary artery x-rays, or angiography) with…
- Trial name
- NCT04258228
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Cardiac Pacemaker, Artificial
Imaging Study of Lead Implant for His Bundle Pacing
The purpose of this research study is to assess the implant success proportion of the Medtronic SelectSecure MRI SureScan Model 3830 pacing lead at the bundle of His for His bundle pacing.
- Trial name
- (IMAGE-HBP) (NCT03294317)
- Testing
- His bundle pacing
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Heart Failure, Congestive, Cardiac Pacing, Artificial
Acoustic Cardiographic Assessment of Heart Function and the Role of Phrenic Nerve Stimulation
In this study, the investigators sought to determine whether a stimulation of the phrenic nerve affects heart function. Heart function is assessed by acoustic cardiography.
- Conditions
- Heart Failure, Congestive, Cardiac Pacing, Artificial, Transcutaneous Electric Nerve Stimulation
- Trial name
- NCT00541541
- Testing
- Phrenic nerve stimulation
- Where
- Switzerland
- Sponsor
- Luzerner Kantonsspital
Congestive Heart Failure, Atrial Fibrillation
Study to Characterize Atrial Fibrillation in CHF Patients Indicated for CRT
The purpose of the study is to characterize atrial arrhythmias in patients indicated for Cardiac Resynchronization Therapy (CRT) and to monitor changes in atrial arrhythmias while CRT is provided.
- Trial name
- NCT00156728
- Testing
- Vitatron biventricular pacemaker
- Where
- 23 sites in Czechia, France and 5 more
- Volunteers
- 172 people
- Sponsor
- Medtronic BRC
Bradyarrhythmias, Arrhythmias
Thromboembolic Complications After Pacemaker or Implantable Cardioverter-Defibrillator Procedures
This is a large prospective registry of patients submitted to cardiac electronic devices implantation designed to investigate the incidence, risk factors and prognostic of thromboembolic complications associated with transvenous…
- Conditions
- Bradyarrhythmias, Arrhythmias, Cardiovascular Disease, Venous Thrombosis
- Trial name
- NCT01717495
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Sao Paulo
Heart Failure
AI-Guided Left Bundle Branch Area Pacing
The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.
- Trial name
- NCT07206602
- Testing
- AI-assisted Left Bundle Branch Area Pacing, Left Bundle Branch Area Pacing
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Mayo Clinic