Clinical trials: Cardiac Arrest (CA)
Cardiac Arrest (CA)
Optimal Ventilation for Cardiac Arrest
Pediatric cardiac arrest is a life-threatening problem affecting >15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors.
- Trial name
- OPTI-VENT (NCT07114510)
- Testing
- OPTI-VENT Bundle, Transition, None - control
- Where
- 20 sites in United States
- Volunteers
- 1,530 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest (CA)
Hand Position, CPR Quality and Rescuer Comfort
This randomized crossover simulation study will compare two hand positions used during chest compressions: interlocked fingers and non-interlocked hands placed one on top of the other.
- Trial name
- NCT07825805
- Testing
- Interlocked-finger chest compression technique, Overlapped hands chest compression technique
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Cardiac Arrest (CA)
Self-training and Resuscitation Techniques: Evaluation of the Performance and Impact on the Quality of Cardiopulmonary Resuscitation (CPR)
Cardiac arrest (CA) remains one of the leading causes of death worldwide, and its incidence continues to increase. The median survival rate following in-hospital cardiac arrest in France is 19%.
- Trial name
- ATIPIQ (NCT07820605)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Care Medicine, Emergency Medical Services
The TTM and ASM Trial
Sudden cardiac arrest (SCA) remains one of the major challenges in clinical care. Although improvements in resuscitation quality have increased the likelihood of return of spontaneous circulation (ROSC), most patients still fail…
- Conditions
- Critical Care Medicine, Emergency Medical Services, Cardiac Arrest (CA), Seizure
- Trial name
- NCT07835802
- Testing
- Prophylactic ASM, Hypothermic, Normothermic
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest (CA), Anoxic Brain Injury
Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest
WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838.
- Conditions
- Cardiac Arrest (CA), Anoxic Brain Injury, Comatose Survivors of Cardiac Arrest, EEG
- Trial name
- WAKE-OHCA (NCT06979700)
- Testing
- Automated Pupillometry, Transcranial Doppler Ultrasound, Optic Nerve Sheath Diameter
- Where
- 2 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Cardiac Arrest (CA)
Which Position Is Better For CPR In OHCA Patients?
Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position
- Trial name
- NCT07002775
- Testing
- Transesophageal ultrasound
- Where
- 2 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest (CA)
Ventilation During CPR and Return of Spontaneous Circulation
During cardiopulmonary resuscitation (CPR), rescue breaths help move air into the lungs, but the amount of air delivered is rarely measured.
- Trial name
- NCT07834294
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA)
The Application of Positive End-Expiratory Pressure in Out-of-Hospital Cardiac Arrest: The Lazarus-PEEP Trial.
The goal of this clinical trial is to learn whether using Positive End-Expiratory Pressure (PEEP) during cardiopulmonary resuscitation (CPR) improves outcomes for adults who experience out-of-hospital cardiac arrest, a condition…
- Conditions
- Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA), Positive End-expiratory Pressure (PEEP), Ventilation During Resuscitation
- Trial name
- Lazarus-PEEP (NCT06939335)
- Testing
- Disposable PEEP Valve set at 5 cm H20., Controle
- Where
- 7 sites in Belgium, France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Ghent
Cardiac Arrest (CA)
GARDE : GC7 (N1-guanyl-1,7 Diaminoheptane) cARDiac arrEst
Cardiac arrest (CA) with return of spontaneous circulation is associated with high mortality, exceeding 90% in out-of-hospital settings and approaching 50% in in-hospital settings.
- Trial name
- GARDE (NCT07468292)
- Testing
- GC7 exposure, No GC7 exposure
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova