Clinical trials: Carbon Monoxide Poisoning
Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy for Comatose Patients With Acute Carbon Monoxide Poisoning
Carbon monoxide poisoning still places a burden on the healthcare system worldwide. While oxygen therapy is the cornerstone treatment, the role and practical modalities of hyperbaric oxygen therapy (HBO) remain controversial.
- Trial name
- NCT01099995
- Testing
- Hyperbaric oxygen therapy
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University of Versailles
Carbon Monoxide Intoxication
Suspected Cases of Carbon Monoxide Poisoning
The purpose of this study is to collect non-invasive opportunity sample data in suspected or known cases of carbon monoxide poisoning.
- Trial name
- NCT02950701
- Testing
- Observational data collection.
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Nonin Medical, Inc
Carbon Monoxide Poisoning From Fire Accidents
Is it Possible to Treat Cyanide Poisoning With HBO?
People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO).
- Trial name
- NCT00399100
- Testing
- HBO - hyperbaric oxygen treatment
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Carbon Monoxide Exposure
End-Tidal Carbon Dioxide as a Measure of Carboxyhemoglobin in Carbon Monoxide Poisoning
The purpose of this study is to determine whether a relationship exists between EtCO2 and carboxyhemoglobin levels in carbon monoxide exposure.
- Trial name
- NCT01859156
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Hennepin Healthcare Research Institute
Carbon Monoxide Poisoning
Cognitive and Blood Biomarker Assessment After CO Exposure
Carbon monoxide (CO) is reported to cause around 30 deaths, 200 admissions and 4000 presentations to Emergency Departments each year in the UK.
- Trial name
- NCT04475263
- Volunteers
- 50 people
- Sponsor
- St George's, University of London
Delayed Encephalopathy After Carbon Monoxide Poisoning
Treatment of Human Cord Blood Mononuclear Cell for Delayed Encephalopathy After Carbon Monoxide Poisoning
The effects and safety of Human cord blood mononuclear cell for delayed encephalopathy after carbon monoxide poisoning
- Trial name
- NCT02952716
- Testing
- Human cord blood mononuclear cell, hyperbaric oxygen
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Liaocheng People's Hospital
Tobacco Smoke Pollution, Maternal Exposure During Pregnancy
Prenatal Tobacco Exposure and Newborn Outcomes: A Maternal Urinary Cotinine Study
Prenatal exposure to tobacco smoke, through either active maternal smoking or secondhand exposure, has been associated with impaired fetal oxygenation, metabolic stress, and adverse early neonatal outcomes.
- Conditions
- Tobacco Smoke Pollution, Maternal Exposure During Pregnancy, Infant, Newborn, Carbon Monoxide Poisoning
- Trial name
- NCT07201181
- Testing
- Maternal Urinary Cotinine Assessment
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Carbon Monoxide-induced Parkinsonism
Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication
The study purpose is to determine the clinical values of 18F-FP-(+)-DTBZ in the diagnosis of Parkinsonism in patients with carbon monoxide intoxication, regional distribution and its correlation with clinical parameters.
- Trial name
- NCT02138864
- Testing
- 18F-FP-(+)-DTBZ
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Carbon Monoxide Intoxication
Evaluation of CO Intoxication Rate, by CAPillary HbCO
The main goal of COCAP is to compare COHb (carboxyhemoglobin) levels measured from venous or arterial samples with those measured from capillary samples in patients suspected of Carbon Monoxide intoxication.Patient participation…
- Trial name
- COCAP (NCT06641752)
- Testing
- Blood drop sampling
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Nantes University Hospital
Carbon Monoxide Poisoning
Role of Pulse Co-oximetry for Detecting Carbon Monoxide Poisoning in the Prehospital Emergency Medical Service Setting
The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard laboratory blood gas analysis (COHb) have…
- Trial name
- CO-OX (NCT02860455)
- Testing
- RAD57 measurement (SpCO), CO-oximeter
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Montpellier
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Carbon Monoxide Poisoning
The Efficacy of L-Carnitine in the Management of Acute Carbon Monoxide Poisoning
Carbon monoxide (CO) poisoning results in high morbidity and mortality worldwide. CO is described as a "silent killer" because CO is colorless, odorless, and tasteless but highly toxic.
- Trial name
- NCT05647707
- Testing
- L-Carnitine
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Coma, Carbon Monoxide Poisoning
Carbon Monoxide-induced Coma: Prognostic Factors
The primary objective of the study is to determine prognostic factors for hospital-mortality following carbon monoxide (CO)-induced coma.
- Trial name
- Coma-CO (NCT03926494)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carbon Monoxide Poisoning
One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning
This randomized trial will investigate important clinical outcomes of patients with acute carbon monoxide poisoning randomized to receive either one or three hyperbaric oxygen treatments.
- Trial name
- 1V3CORCT (NCT00465855)
- Testing
- Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Intermountain Health Care, Inc.
Carbon Monoxide Poisoning
Normal Quantitative EEG (qEEG) Dataset
In this study, the investigators will collect EEG data in normal, healthy volunteers without a history of prior brain injury. This data will be analyzed by computer (quantitative, or qEEG) and stored in a normative database so…
- Trial name
- NormalEEG (NCT02375126)
- Testing
- Electroencephalography
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Hyperbaric Oxygen Therapy, Carbon Monoxide Poisoning
Optimal Number of Hyperbaric Oxygen Treatments for Carbon Monoxide Poisoning
The optimal treatment strategy with hyperbaric oxygen therapy has been the subject of some debate over the past 3 decades. Initial landmark studies showed a decrease in the incidence of DNS with a single treatment and also with…
- Trial name
- NCT06619717
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Alberta
Carbon Monoxide Poisoning, Carbon Monoxide Intoxication
Carbon Monoxide Hyperbaric Oxygen With Steroid Therapy
Hyperbaric Oxygen Therapy (HBO) is routine treatment of carbon monoxide (CO) poisoning to prevent delayed neurological sequelae. This study looking to see if neurologic outcomes are improved with the addition of dexamethasone.
- Conditions
- Carbon Monoxide Poisoning, Carbon Monoxide Intoxication, Carbon Monoxide Encephalopathy, Carbon Monoxide-induced Parkinsonism
- Trial name
- CODex (NCT06574048)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Carbon Monoxide Poisoning
Microparticles Blood Level in Acute Carbon Monoxide Poisoning
The goal of this pilot, clinical, experimental, biological and prospective study with uso of biological material (venous blood sampling), in patient with acute carbon monoxide (CO) intoxication and in a group of healthy…
- Trial name
- COMPs (NCT05591300)
- Testing
- Microparticles research
- Where
- Italy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Carbon Monoxide Poisoning
Neurological Sequelae in Patients With Acute Carbon Monoxide Poisoning
The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
- Trial name
- NCT04925297
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,250 people
- Sponsor
- The First Hospital of Jilin University
Carbon Monoxide Poisoning, Delayed Neurocognitive Sequelae
The Efficacy of Dexamethasone in Combination With N-acetylcysteine in Preventing Neurocognitive Sequelae Due to Carbon Monoxide Poisoning
Background and Aim: Carbon monoxide (CO) poisoning is a significant public health issue that can cause delayed neuropsychological sequelae (DNS). DNS mechanisms involve oxidative stress, inflammation, and immune injury.
- Trial name
- NCT06811675
- Testing
- Dexamethasone and N-acetylcysteine (NAC)
- Where
- Taiwan
- Volunteers
- 128 people
- Sponsor
- China Medical University Hospital